PD Dr. Oliver Schwardt
Wissenschaftlicher Mitarbeiter
Lehrbeauftragter

Oliver Schwardt

Philosophisch-Naturwissenschaftliche Fakultät

Departement Pharmazeutische Wissenschaften

Molekulare Pharmazie

Wissenschaftlicher Mitarbeiter

Klingelbergstrasse 50
4056 Basel
Schweiz

Tel. +41 61 207 15 54
oliver.schwardt@unibas.ch


Philosophisch-Naturwissenschaftliche Fakultät

Departement Pharmazeutische Wissenschaften

Molekulare Pharmazie

Lehrbeauftragter

Klingelbergstrasse 50
4056 Basel
Schweiz

Tel. +41 61 207 15 54
oliver.schwardt@unibas.ch

Curriculum Vitae

 

Oliver Schwardt graduated in chemistry in 1995 at the University of Stuttgart, Germany. In 1999 he completed his Ph.D. thesis titled Stereoselective Synthesis of 4-Amino-1,2,3-triols – Important Building Blocks for the Preparation of Nitrogen-containing Natural Compounds and Drugs under the guidance of Prof. Volker Jäger at the University of Stuttgart. During that time Oliver stayed for two months at the Institut de Chimie des Substances Naturelles (ICSN-CNRS) in Gif-sur-Yvette, France, funded by the Deutscher Akademischer Austauschdienst (DAAD) to work on in vitro cytotoxicity tests. From 1999 to 2000 he worked as a post-doctoral fellow on chemical and chemo-enzymatic synthesis of oligosaccharides at Novartis Pharma AG, Basel. In October 2000 Oliver joined the Molecular Pharmacy group at the University of Basel as senior scientist and lecturer. In May 2015 he received "Habilitation" and was promoted to "Privatdozent" (Senior Lecturer) in the field of Pharmaceutical Sciences.

The main topic of his research is the rational design, synthesis and characterization of peptide-, protein- and carbohydrate-based ligands for therapeutically relevant immune regulatory proteins.

 

Schönemann, W., Cramer, J., Mühlethaler, T., Fiege, B., Silbermann, M., Rabbani, S., Dätwyler, P., Zihlmann, P., Jakob, R. P., Sager, C. P., Smiesko, M., Schwardt, O., Maier, T. und Ernst, B. (2019) «Improvement of Aglycone π-Stacking Yields Nano- to Subnanomolar FimH Antagonists», ChemMedChem, S. aheadofrint. doi: 10.1002/cmdc.201900051.   
Pang, L., Bezençon, J., Kleeb, S., Rabbani, S., Sigl, A., Smiesko, M., Sager, C. P., Eris, D., Schwardt, O. und Ernst, B. (2017) «FimH antagonists - solubility vs. permeability», in Ratuer, A. P., Lindhorst, T. K., und Queneau, Y. (Hrsg.) Carbohydrate Chemistry. London: Royal Society of Chemistry (A specialist periodical report), S. 248-273. doi: 10.1039/9781782626657-00248.   edoc
Frei, P., Pang, L., Silbermann, M., Eriş, D., Mühlethaler, T., Schwardt, O. und Ernst, B. (2017) «Target-directed Dynamic Combinatorial Chemistry: A Study on Potentials and Pitfalls as Exemplified on a Bacterial Target», Chemistry - A European Journal. Wiley, 23(48), S. 11570-11577. doi: 10.1002/chem.201701601.   edoc