Aktuelle Masterarbeitsthemen der Forschungsgruppe Pharmazeutische Technologie
Current Master's Theses-Projects of the Research Group in Pharmaceutical Technology

 

Forschungsgebiet
Research Field
Kontakt Betreuer/in
Contact Supervisor
MSc PharmazieMSc Drug SciencesBemerkungen
Comments
Implementation and validation of zebrafish embryos to assess renal clearance of small molecules and nanocarriersDr. Sandro Sieber
jaja
Cell derived materials for design of drug delivery systemsDr. Tomaz Einfaltjaja
Development and characterization of a solid lipid-based formulationMaryam Farzanjaja
Lipid modified FCC formulation for CyclosporineDr. Gabriela Québattejaja
Superparamagnetic iron oxide nanoparticles for targeting, drug delivery and imaging in (higher) vertebratesEmre Cörekjaja
Human xenotransplanted zebrafish embryos as an early screening tool for FcRn mediated prolonged circulation of therapeutic proteins

Scope: Identify cell lines with highest FcRn expression and perform preliminary screening in zebrafish embryos with fluorescently labelled proteins.
Dr. Anna Pratsinisjaja

Design and delivery of an oncolytic protein for cancer treatment

Scope: Enhance cytotoxic effects of an oncolytic protein and evaluate its mode of action using various  molecular biology techniques

Patrick Hauswirthjaja

Identify possible synergies between certain UV filters and emulsifiers

The efficacy of a sunscreen depends primarily on the composition of the UV filters contained in the products. However, it was shown that the sun protection factor (SPF) may vary between two sunscreens containing the same UV filter system but differing in other aspects of the preparation. This implies that further factors also impact the photoprotection afforded by the product, such as the formulation excipients. 

In the thesis, the effect of different emulsifiers on the UV performance of the product shall be investigated. To this purpose, sunscreen formulations differing in their emulsifying system will be prepared and evaluated in respect of their UV performance including the in vitro measurement of the SPF and UVA protection factor (UVA-PF). The homogeneity of the emulsion is evaluated by light microscopy.
Dr. Myriam SohnjajaBASF Grenzach GmbH
Pharmaceutical Development of Biologics
LonzajajaLonza
Process optimization with a focus on hot-melt extrusion

Marco Fröhlich

jajaAbbVie Deutschland GmbH & Co.KG
PBPK and PK/PD modelingDr. Thierry LavéjajaF. Hoffmann-La Roche Ltd
SCAHT - Swiss Centre for Applied Human Toxicology
Regulatory Toxicology: Mechanisms of Toxicity of engineered nanomaterials
Dr. Jenny Sandströmjajascaht