/ Forschung

Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing


Defective insulin processing is associated with obesity and diabetes. Prohormone convertase 1/3 (PC1/3) is an endopeptidase required for the processing of neurotransmitters and hormones. PC1/3 deficiency and genome-wide association studies relate PC1/3 with early onset obesity.  Read more