Publications Adherence


Dietrich F, Zeller A, Allemann S, Arnet I. Development and acceptance of a new adherence monitoring package to identify non-adherent patients with polypharmacy in primary care: a feasibility study. BMJ Open Quality 2023;12:e002155. doi: 10.1136/bmjoq-2022-002155.

Tan M, Allemann SS, Qin XS, D'Souza WJ. Adherence patterns in antiseizure medications (ASM) influencing risk of Sudden Unexplained Death in Epilepsy (SUDEP): a data linkage study using dispensed prescriptions. Epilepsia. 2023 Jan 8. doi: 10.1111/epi.17502. Epub ahead of print. PMID: 36617371.


Dalli, L. L., Kilkenny, M. F., Arnet, I., Sanfilippo, F. M., Cummings, D. M., Kapral, M. K., ... & Cadilhac, D. A. (2022). Towards better reporting of the Proportion of Days Covered method in cardiovascular medication adherence: A scoping review and new tool TEN‐SPIDERS. British Journal of Clinical Pharmacology.

Dima, A. L., Allemann, S. S., Dunbar‐Jacob, J., Hughes, D. A., Vrijens, B., & Wilson, I. B. (2022). Methodological considerations on estimating medication adherence from self‐report, electronic monitoring, and electronic healthcare databases using the TEOS framework. British Journal of Clinical Pharmacology.

Baumgartner, Pascal C., et al. "Development and testing of a framework for defining a strategy to address medication adherence during patient encounters in community pharmacies." Exploratory Research in Clinical and Social Pharmacy (2022): 100123.

Baumgartner, Pascal C., et al. "Delta T, a Useful Indicator for Pharmacy Dispensing Data to Monitor Medication Adherence." Pharmaceutics 14.1 (2022): 103.


Dietrich F, Zeller A, Haag M, Hersberger KE, Arnet I. Communicating Electronic Adherence Data to Physicians—Consensus-Based Development of a Compact Reporting Form. Int. J. Environ. Res. Public Health 2021, 18, 10264. DOI: 10.3390/ijerph181910264.Publication

Rothen JP, Rutisauser J, Walter P, Hersberger KE, Arnet I. Vitamin D oral intermittent treatment (DO IT) study, a randomized clinical trial with individual loading regimen. Sci Rep 2021;11:18746. Publication

Haag M, Hersberger KE, Arnet I. Assessing medication adherence barriers to short-term oral antibiotic treatment in primary care - development and validation of a self-report questionnaire (BIOTICA). Int. J. Environ. Res. Public Health 2021, 18, 7768. DOI: 10.3390/ijerph18157768. Publication

Dietrich F, Polymeris AA, Verbeek M, Engelter ST, Hersberger KE, Schaedelin S, Arnet I, Lyrer PA. Impact of the COVID-19 lockdown on the adherence of stroke patients to direct oral anticoagulants: a secondary analysis from the MAAESTRO study. J Neurol 2021 DOI: 10.1007/s00415-021-10631-5.Publication


Albert V, Polymeris AA, Dietrich FM, Engelter ST, Hersberger KE, Schaedelin S, Lyrer PA, Arnet I. Insights into direct oral anticoagulant therapy implementation of stroke survivors with atrial fibrillation in an ambulatory setting. J. Stroke Cerebrovasc. Dis. 2021. DOI: 10.1016/j.jstrokecerebrovasdis.2020.105530. Publication

Dietrich FM, Hersberger KE, Arnet I. Benefits of medication charts provided at transitions of care: a narrative systematic review. BMJ Open 2020;10:e037668. DOI: 10.1136/bmjopen-2020-037668. Publication

Arnet I, Messerli M, Oezvegy J, Hersberger KE, Sahm LJ. Translation to English, cross-cultural adaptation, and pilot testing of the self-report questionnaire on swallowing difficulties with medication intake and coping strategies (SWAMECO) for adults with polypharmacy. BMJ Open 2020. DOI: 10.1136/bmjopen-2020-036761. Publication

Rothen JP, Rutishauser J, Walter P, Hersberger KE, Arnet I. Oral intermittent vitamin D substitution: influence of pharmaceutical form and dosage frequency on medication adherence: a randomized clinical trial. BMC Pharmacol Toxicol 2020. DOI: 10.1186/s40360-020-00430-5. Publication

Greenland M, Knuiman MW, Hung J, Nedkoff L, Arnet I, Rankin JM, Kilkenny MF, Sanfilippo FM. Cardioprotective medication adherence in Western Australians in the first year after myocardial infarction: restricted cubic spline analysis of adherence-outcome relationships. Sci Rep 2020;10:4315. DOI: 10.1038/s41598-020-60799-5. Publication

Haag M, Lehmann A, Hersberger KE, Schneider MP, Gauchet A, Vrijens B, Arnet I, Allenet B. The ABC taxonomy for medication adherence translated into French and German. Br J Clin Pharmacol 2019;86(4):734-744. DOI: 10.1111/bcp.14172. Publication

Arnet I, Rothen JP, Hersberger KE. Validation of a novel electronic device for medication adherence monitoring of ambulatory patients. Pharmacy Basel 2019;20;7(4):155. DOI: 0.3390/pharmacy7040155. Publication

Damen NL, Van den Bemt BJF, Hersberger KE, Papastergiou J, Alves da Costa F, Rydant S, Wartenberg NS, Lobban T, Arnet I, Antoniou S. Creating an interprofessional guideline to support patients receiving oral anticoagulation therapy: a Delphi exercise. Int J Clin Pharm 2019;41,1012–1020. DOI: 10.1007/s11096-019-00844-0. Publication

Wentzky V, Polymeris AA, Hersberger KE, Engelter ST, Schaedelin S, Arnet I, Lyrer PA. Protocol for MAAESTRO: Electronic monitoring and improvement of adherence to direct oral anticoagulant treatment—a randomized crossover study of an educational and reminder-based intervention in ischemic stroke patients under polypharmacy. Front Neurol 2018; 9:1134. DOI: 10.3389/fneur.2018.01134. Publication

Baumgartner PC, Haynes RB, Hersberger KE, Arnet I. A systematic review of medication adherence thresholds dependent of clinical outcomes. Front Pharmacol 2018;9:1290. DOI: 10.3389/fphar.2018.01290. Publication

Arnet I, Greenland M, Knuiman MW, Rankin JM, Hung J, Nedkoff L, Briffa TG, Sanflippo FM. Operationalization and validation of a novel method to calculate adherence to polypharmacy with refill data from the Australian pharmaceutical benefits scheme (PBS) database. Clin Epidemiol 2018;10:1181-94. Publication

Metaxas C, Wentzky V, Stahl M, Hersberger KE, Arnet I.  Development and validation of a questionnaire to self-assess patient knowledge of direct oral anticoagulants (KODOA-test). Drug Healthc Patient Saf 2018;10:69-77. DOI: 10.2147/DHPS.S152954. Publication

Arnet I, Haag M, Hersberger KE. Initiierung, Implementierung, Abbruch – Die neue Taxonomie der Adhärenz und ihre Bedeutung für die Betreuung von Epilepsiepatienten. Epileptologie 2017;34:52-59.  Publication

Hersberger KE, Imfeld-Isenegger TL, Arnet I. Mögliche Beiträge der Apotheke bei der medikamentösen Epilepsiebehandlung. Epileptologie 2017;34:60-68. Publication

Arnet I, Hersberger KE. Malcompliance. Wie können Patienten motiviert werden? Der Informierte Arzt 2017;10:16-19. Publication

Allemann SS, Nieuwlaat R, Navarro T, Haynes B, Hersberger KE, Arnet I. Congruence between patient characteristics and interventions may partly explain medication adherence intervention effectiveness: An analysis of 190 randomized controlled trials from a Cochrane systematic review. J Clin Epidemiol 2017;91:70-79. DOI: 10.1016/j.jclinepi.2017.07.011. Publication

Wentzky V, Lanz M, Imanidis G, Hersberger KE, Arnet I. Stability of medicines after repackaging into multicompartment compliance aids: eight criteria for detection of visual alteration. Drugs Ther Perspect 2017;33(10):487-496. DOI: 10.1007/s40267-017-0431-9. Publication

Arnet I, Allemann SS, Dürsteler KM, Strasser J, Vogel M, Hersberger KE. Novel medication supply model guarantees adequate management and high adherence to polypharmacy in older opioid users – preliminary results with outpatients. J Aging Sci 2017;5:176. DOI: 10.4172/2329-8847.1000176.  Publication

Loscertales HR, Wentzky V, Dürsteler KM, Strasser J, Hersberger KE, Arnet I. Successful withdrawal from high-dose benzodiazepine in a young patient through electronic monitoring of polypharmacy: a case report in an ambulatory setting.Ther Adv Psychopharmacol 2017;7(5):181-187. DOI: 10.1177/2045125317690502.  Publication

Arnet I, Schacher S, Balmer E, Koeberle D, Hersberger KE. Poor adhesion of fentanyl transdermal patches may mimic end-of-dosage failure after 48 hours and prompt early patch replacement in hospitalized cancer pain patients. J Pain Res 2016;9(9):993-999. DOI: 10.2147/JPR.S116091. Publication

Arnet I, Kooij MJ, Messerli M, Hersberger KE, Heerdink ER, Bouvy M. Proposal of standardization to assess adherence with medication records: methodology matters. Ann Pharmacother 2016;50(5):360-8. DOI: 10.1177/1060028016634106. Publication

Alleman SS, Hersberger KE, Arnet I. Patient views on an electronic dispensing device for prepackaged polypharmacy: a qualitative assessment in an ambulatory setting. Integr Pharm Res Pract 2015;4:167-174. Publication

Boeni F, Arnet I, Hersberger KE. Adherence counseling during patient contacts in Swiss community pharmacies. Patient Prefer Adherence 2015;24(9):597-605. DOI: 10.2147/PPA.S76027. Publication

Arnet I, Metaxas C, Walter PN, Morisky DE, Hersberger KE. The 8-item morisky medication adherence scale translated in German and validated against objective and subjective polypharmacy adherence measures in cardiovascular patients. J Eval Clin Pract 2015;21(2):271-7; DOI: 10.1111/jep.12303. Publication

Boeni F, Hersberger KE, Arnet I. Success of a sustained pharmaceutical care service with electronic adherence monitoring in patient with diabetes over 12 months. BMJ Case Rep 2015. DOI: 10.1136/bcr-2014-208672. Publication

Boeni F, Hersberger KE, Arnet I. Multidrug punch cards in primary care: a mixed methods study on patients' preferences and impact on adherence. Front Pharmacol 2014;5:220. DOI: 10.3389/fphar.2014.00220. Publication

Boeni F, Spinatsch E, Suter K, Hersberger KE, Arnet I. Effect of drug reminder packaging on medication adherence: a systematic review revealing research gaps. Syst Rev 2014;3(1):29. DOI: 10.1186/2046-4053-3-29. Publication

Structured Abstract included in the Database of Abstracts of Reviews of Effects (DARE) by The Center of Reviews and Disseminatin (CRD).

Arnet I, Abraham I, Messerli M, Hersberger KE. A method for calculating adherence to polymedication from dispensing data records. Int J Clin Pharm 2014;36(1):192-201. DOI: 10.1007/s11096-013-9891-8. Publication

Hersberger KE, Boeni F, Arnet I. Dose-dispensing service as an intervention to improve adherence to polymedication. Expert Rev Clin Pharmacol 2013;6(4):413-21. Publication

Arnet I, Walter P, Hersberger KE. Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence. Front. Pharmacol 2013;4:26. Publication

Walter P, Tsakiris DA, Romanens M, Arnet I, Hersberger KE. Pattern of timing adherence could guide recommendations for personalized intake schedules. J Pers Med 2012;2:267-276. Publication

Arnet I, Hersberger KE. Polymedication Electronic Monitoring System (POEMS) - Introducing a new technology as gold standard for compliance measurement. J Pat Comp 2012;2(1):50-51. Publication

Arnet I, Bucher H, Hersberger KE. Polymedication Electronic Monitoring System (POEMS) in future research. Ann Int Med [comment to Thompson et al.] 2012. DOI: 10.7326/0003-4819-156-11-201206050-00419.  Publication

Arnet I, Hersberger KE. Compliance-Förderung – eine vernachlässigte Intervention. Care Management 2010;3(5):7-12. Publication

Arnet I, Hersberger KE. Verbesserungen der Compliance durch die Aportheke. Ther Umschau 2010;67(6):293-301.  Publication

Hersberger KE, Arnet I. Pharmaceutical Care – a new discipline in the curriculum: Introducing pharmacy students to medication non-compliance. Chimia 2006;60:76-79. Publication