2021

Duthaler, U., Weber, M., Hofer, L., Chaccour, C., Maia, M., Müller, P., Krähenbühl, S. and Hammann, F. (2021) “The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes”, PLoS Pathogens. Public Library of Science, 17(3), p. e1009382. doi: 10.1371/journal.ppat.1009382.   edoc | Open Access
Wagner-Hattler, L., Kiene, K., Bielicki, J., Pfister, M., Puchkov, M. and Huwyler, J. (2021) “High Acceptability of an Orally Dispersible Tablet Formulation by Children”, Children. MDPI, 8(3), p. 194. doi: 10.3390/children8030194.   edoc
Spoendlin, J., Blozik, E., Graber, S. M., Rauch, M., Marxer, C. A., Rüegg, S., Meier, C., Winterfeld, U. and Panchaud, A. (2021) “Use of valproate in pregnancy and in women of childbearing age between 2014 and 2018 in Switzerland: a retrospective analysis of Swiss healthcare claims data”, Swiss medical weekly. EMH Schweizerischer Ärzteverlag, 151, p. w20386. doi: 10.4414/smw.2021.20386.   edoc
Einfalt, T., Detampel, P., Häussinger, D., Casper, J., Meier, C., Puchkov, M. and Huwyler, J. (2021) “Hydroxychloroquine immediate release tablets: Formulation and evaluation of a solid dosage form”, ChemRxiv Preprint. doi: 10.26434/chemrxiv.14170508.v1.   edoc | Open Access
Schnoz, C., Moser, S., Kratschmar, D. V., Odermatt, A., Loffing-Cueni, D. and Loffing, J. (2021) “Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC”, Pflügers Archiv : European journal of physiology. Springer, 473(1), pp. 79–93. doi: 10.1007/s00424-020-02491-1.   edoc | Open Access
Beck, K. R. and Odermatt, A. (2021) “Antifungal therapy with azoles and the syndrome of acquired mineralocorticoid excess”, Molecular and Cellular Endocrinology. Elsevier, 524, p. 111168. doi: 10.1016/j.mce.2021.111168.   edoc | Open Access
Inderbinen, S. G., Zogg, M., Kley, M., Smieško, M. and Odermatt, A. (2021) “Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole”, Toxicology and applied pharmacology. Academic Press, 412, p. 115387. doi: 10.1016/j.taap.2020.115387.   edoc | Open Access
Leuppi-Taegtmeyer, A. B., Reinau, D., Yilmaz, S., Rüegg, S., Krähenbühl, S., Jick, S. S., Leuppi, J. D. and Meier, C. R. (2021) “Antiseizure drugs and risk of developing smoking-related chronic obstructive pulmonary disease or lung cancer: A population-based case-control study”, British Journal of Clinical Pharmacology. Wiley, 87(3), pp. 1253–1263. doi: 10.1111/bcp.14501.   edoc
Pinto, M. E. F., Chan, L. Y., Koehbach, J., Devi, S., Gründemann, C., Gruber, C. W., Gomes, M., Bolzani, V. S., Cilli, E. M. and Craik, D. J. (2021) “Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes”, Journal of natural products, p. Pub ahead of print. doi: 10.1021/acs.jnatprod.0c01069.   
Wang, J. T., Danton, O., Treyer, A. and Hamburger, M. (2021) “Development of a solid-supported cysteinyl probe for the isolation of electrophiles from plant pollen extracts”, Talanta, 228, p. 122216. doi: 10.1016/j.talanta.2021.122216.   
Schittny, A., Waldner, S., Duthaler, U., Vorobyev, A., Abramovich, R., Krähenbühl, S., Puchkov, M. and Huwyler, J. (2021) “Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans”, pharmaceutics, 13(401), pp. 1–17. doi: 10.3390/pharmaceutics13030401.   
Schuster, J., Probst, C. E., Mahler, H.-C., Joerg, S., Huwyler, J. and Mathaes, R. (2021) “Assessing Particle Formation of Biotherapeutics in Biological Fluids”, Journal of Pharmaceutical Sciences, 110(4), pp. 1527–1532. doi: 10.1016/j.xphs.2020.12.038.   
Dopler, A., Stibitzky, S., Hevey, R., Mannes, M., Guariento, M., Höchsmann, B., Schrezenmeier, H., Ricklin, D. and Schmidt, C. Q. (2021) “Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces”, Frontiers in immunology, 12, p. 615748. doi: 10.3389/fimmu.2021.615748.   
Keller, M., Fankhauser, S., Giezendanner, N., König, M., Keresztes, F., Danton, O., Fertig, O., Marcourt, L., Hamburger, M., Butterweck, V. and Potterat, O. (2021) “Saponins from Saffron Corms Inhibit the Gene Expression and Secretion of Pro-Inflammatory Cytokines”, J. Nat. Prod, 84, pp. 630–645. doi: 10.1021/acs.jnatprod.0c01220.   
Chabane, S., Boudjelal, A., Keller, M., Doubakh, S. and Potterat, O. (2021) “Teucrium polium - wound healing potential, toxicity and polyphenolic profile”, South African Journal of Botany, 137, pp. 228–235. doi: 10.1016/j.sajb.2020.10.017.   
Santos, S., Zurfluh, L., Mennet, M., Potterat, O., von Mandach, U., Hamburger, M. and Simões-Wüst, A. P. (2021) “Bryophyllum pinnatum compounds inhibit oxytocin-induced signalling pathways in human myometrial cells”, Frontiers Pharmacol, 12, p. 632986. doi: 10.3389/fphar.2021.632986.   
Fischer, A., Smie�ko, M., Sellner, M. and Lill, M. A. (2021) “Decision Making in Structure-Based Drug Discovery: Visual Inspection of Docking Results”, Journal of medicinal chemistry, 64(5), pp. 2489–2500. doi: 10.1021/acs.jmedchem.0c02227.   
Fischer, A., Sellner, M., Mitusińska, K., Bzówka, M., Lill, M. A., Góra, A. and Smie�ko, M. (2021) “Computational Selectivity Assessment of Protease Inhibitors against SARS-CoV-2”, International journal of molecular sciences, 22(4), p. 2065. doi: 10.3390/ijms22042065.   
Fischer, A., Häuptli, F., Lill, M. A. and Smie�ko, M. (2021) “Computational Assessment of Combination Therapy of Androgen Receptor-Targeting Compounds”, Journal of chemical information and modeling, 61(2), pp. 1001–1009. doi: 10.1021/acs.jcim.0c01194.   
Fischer, A., Frehner, G., Lill, M. A. and Smie�ko, M. (2021) “Conformational Changes of Thyroid Receptors in Response to Antagonists”, Journal of chemical information and modeling, 61(2), pp. 1010–1019. doi: 10.1021/acs.jcim.0c01403.   
Nicolle, L., Casper, J., Willimann, M., Journot, C. M. A., Detampel, P., Einfalt, T., Grisch-Chan, H. M., Thöny, B., Gerber-Lemaire, S. and Huwyler, J. (2021) “Development of Covalent Chitosan-Polyethylenimine Derivatives as Gene Delivery Vehicle: Synthesis, Characterization, and Evaluation”, International Journal of Molecular Sciences, 22(8), p. 3828. doi: 10.3390/ijms22083828.   

2020

Holandino, C., de Oliveira Melo, M. N., Passos Oliveira, A., da Costa Batista, J. V., Alves Marques Capella, M., Garret, R., Grazi, M., Ramm, H., Dalla Torre, C., Schaller, G., Urech, K., Weissenstein, U. and Baumgartner, S. (2020) “Phytochemical analysis and in vitro anti-proliferative activity of Viscum album ethanolic extracts”, BMC Complementary Medicine and Therapies. BioMed Central, 20(1), p. 215. doi: 10.1186/s12906-020-02987-4.   edoc | Open Access
Haduch, A., Bromek, E., Rysz, M., Pukło, R., Papp, M., Gruca, P., Łasoń, M., Niemczyk, M. and Daniel, W. A. (2020) “The effects of agomelatine and imipramine on liver cytochrome P450 during chronic mild stress (CMS) in the rat”, Pharmacological Reports. Springer, 72(5), pp. 1271–1287. doi: 10.1007/s43440-020-00151-w.   edoc
Bonk, S., Hertel, J., Zacharias, H. U., Terock, J., Janowitz, D., Homuth, G., Nauck, M., Völzke, H., Meyer Zu Schwabedissen, H., Van der Auwera, S. and Grabe, H. J. (2020) “Vitamin D moderates the interaction between 5-HTTLPR and childhood abuse in depressive disorders”, Scientific reports, 10(1), p. 22394. doi: 10.1038/s41598-020-79388-7.   edoc
Patt, M., Gysi, J., Faresse, N., Cidlowski, J. A. and Odermatt, A. (2020) “Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211”, Molecular and cellular endocrinology. Elsevier, 518, p. 110873. doi: 10.1016/j.mce.2020.110873.   edoc | Open Access
Thompson, G. R., Surampudi, P. N. and Odermatt, A. (2020) “Gynecomastia and hypertension in a patient treated with posaconazole”, Clinical case reports. Wiley, 8(12), pp. 3157–3160. doi: 10.1002/ccr3.3376.   edoc | Open Access
Mayr, F., Möller, G., Garscha, U., Fischer, J., Rodríguez Castaño, P., Inderbinen, S. G., Temml, V., Waltenberger, B., Schwaiger, S., Hartmann, R. W., Gege, C., Martens, S., Odermatt, A., Pandey, A. V., Werz, O., Adamski, J., Stuppner, H. and Schuster, D. (2020) “Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction”, International Journal of Molecular Sciences. Molecular Diversity Preservation International, 21(19), p. 7102. doi: 10.3390/ijms21197102.   edoc | Open Access
Tsachaki, M., Strauss, P., Dunkel, A., Navrátilová, H., Mladenovic, N. and Odermatt, A. (2020) “Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration”, Cellular and Molecular Life Sciences. Springer, 77(6), pp. 1153–1175. doi: 10.1007/s00018-019-03227-w.   edoc | Open Access
Nguyen, M.-V. H., Davis, M. R., Wittenberg, R., McHardy, I., Baddley, J. W., Young, B. Y., Odermatt, A. and Thompson, G. R. (2020) “Posaconazole Serum Drug Levels Associated With Pseudohyperaldosteronism”, Clinical Infectious Diseases. Oxford University Press, 70(12), pp. 2593–2598. doi: 10.1093/cid/ciz741.   edoc
Gómez, C., Stücheli, S., Kratschmar, D. V., Bouitbir, J. and Odermatt, A. (2020) “Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples”, Metabolites. MDPI, 10(7), p. 282. doi: 10.3390/metabo10070282.   edoc | Open Access
Schulze, F., Wehner, J., Kratschmar, D. V., Makshana, V., Meier, D. T., Häuselmann, S. P., Dalmas, E., Thienel, C., Dror, E., Wiedemann, S. J., Traub, S., Nordmann, T. M., Rachid, L., De Baat, A., Rohm, T. V., Zhao, C., Odermatt, A., Böni-Schnetzler, M. and Donath, M. Y. (2020) “Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes”, Scientific Reports. Nature Publishing Group, 10(1), p. 3035. doi: 10.1038/s41598-020-59701-0.   edoc | Open Access
Beck, K. R., Thompson, G. R. and Odermatt, A. (2020) “Drug-induced endocrine blood pressure elevation”, Pharmacological Research. Elsevier, 154, p. 104311. doi: 10.1016/j.phrs.2019.104311.   edoc | Open Access
Hughes, S., Gumas, J., Lee, R., Rumano, M., Berger, N., Gautam, A. K., Sfyroera, G., Chan, A. L., Gnanaguru, G., Connor, K. M., Kim, B. J., Dunaief, J. L., Ricklin, D., Hajishengallis, G., Yancopoulou, D., Reis, E. S., Mastellos, D. C. and Lambris, J. D. (2020) “Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates”, Clinical Immunology. Elsevier, 214, p. 108391. doi: 10.1016/j.clim.2020.108391.   edoc
Olcina, M. M., Kim, R. K., Balanis, N. G., Li, C. G., von Eyben, R., Graeber, T. G., Ricklin, D., Stucki, M. and Giaccia, A. J. (2020) “Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis”, iScience. Cell Press, 23(10), p. 101594. doi: 10.1016/j.isci.2020.101594.   edoc
Marxer, C. A., Frey, N., Bodmer, M., Bircher, A., Jick, S. S., Meier, C. R. and Spoendlin, J. (2020) “Survival after Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis: A UK-based Cohort Study”, Journal of Investigative Dermatology. Elsevier. doi: 10.1016/j.jid.2020.09.034.   
Don, C. G. and Smieško, M. (2020) “Deciphering Reaction Determinants of Altered-Activity CYP2D6 Variants by Well-Tempered Metadynamics Simulation and QM/MM Calculations”, Journal of Chemical Information and Modeling. American Chemical Society , 60(12), pp. 6642–6653. doi: 10.1021/acs.jcim.0c01091.   edoc
Potashkin, J., Huang, X., Becker, C., Chen, H., Foltynie, T. and Marras, C. (2020) “Understanding the links between cardiovascular disease and Parkinson’s disease”, Movement disorders : official journal of the Movement Disorder Society. Wiley-Liss, 35(1), pp. 55–74. doi: 10.1002/mds.27836.   edoc
Becker, C., Schwenkglenks, M., Frueh, M., Reich, O. and Meier, C. R. (2020) “Use of selective serotonin reuptake inhibitors, other antidepressant medication, and risk of cataract: a case-control study based on Swiss claims data”, European Journal of Clinical Pharmacology. Springer, 76(9), pp. 1329–1335. doi: 10.1007/s00228-020-02923-y.   edoc
Aicher, L. and Wilks, M. F. (2020) “From risk assessment to regulation”, in Colosio, C., Tsatsakis, A. M., Mandić-Rajćević, S., and Alegakis, A. (eds.) Exposure and Risk Assessment of Pesticide Use in Agriculture - Approaches, Tools and Advances. London: Academic Press, pp. 3–23. doi: 10.1016/B978-0-12-812466-6.00012-9.   edoc
Panajatovic, M. V., Singh, F., Roos, N. J., Duthaler, U., Handschin, C., Krähenbühl, S. and Bouitbir, J. (2020) “PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice”, Acta physiologica (Oxford, England). John Wiley & Sons, 228(4), p. e13402. doi: 10.1111/apha.13402.   edoc
Zhou, X., Bouitbir, J., Liechti, M. E., Krähenbühl, S. and Mancuso, R. V. (2020) “Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones ”, Cells, 9(4), p. 965. doi: 10.3390/cells9040965.   edoc
Zhou, X., Bouitbir, J., Liechti, M. E., Krähenbühl, S. and Mancuso, R. V. (2020) “Para; -Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells ”, International journal of molecular sciences. Multidisciplinary Digital Publishing Institute, 21(8), p. 2841. doi: 10.3390/ijms21082841.   edoc
Bouitbir, J., Alshaikhali, A., Panajatovic, M. V., Abegg, V. F., Paech, F. and Krähenbühl, S. (2020) “Mechanisms of Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in H9c2 Cells and Mice”, European cardiology. Radcliffe Cardiology, 15, p. e33. doi: 10.15420/ecr.2020.15.1.PO10.   edoc
Rudin, D., Schmutz, M., Roos, N. J., Bouitbir, J. and Krähenbühl, S. (2020) “Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis”, Biomedicines. MDPI AG, 8(7), p. 212. doi: 10.3390/biomedicines8070212.   edoc
Roos, N. J., Aliu, D., Bouitbir, J. and Krähenbühl, S. (2020) “Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells ”, Frontiers in pharmacology. Frontiers Media, 11, p. 944. doi: 10.3389/fphar.2020.00944.   edoc
Roos, N. J., Duthaler, U., Bouitbir, J. and Krähenbühl, S. (2020) “The uricosuric benzbromarone disturbs the mitochondrial redox homeostasis and activates the NRF2 signaling pathway in HepG2 cells ”, Free radical biology and medicine. Elsevier, 152, pp. 216–226. doi: 10.1016/j.freeradbiomed.2020.03.009.   edoc
Bouitbir, J., Panajatovic, M. V., Frechard, T., Roos, N. J. and Krähenbühl, S. (2020) “Imatinib and Dasatinib Provoke Mitochondrial Dysfunction Leading to Oxidative Stress in C2C12 Myotubes and Human RD Cells”, Frontiers in Pharmacology. Frontiers Media, 11, p. 1106. doi: 10.3389/fphar.2020.01106.   edoc
Panajatovic, M. V., Singh, F., Duthaler, U., Krähenbühl, S. and Bouitbir, J. (2020) “Role of PGC-1-alpha-associated Mitochondrial Biogenesis in Statin-induced Myotoxicity”, European cardiology. Radcliffe Cardiology, 15, p. e35. doi: 10.15420/ecr.2020.15.1.PO12.   edoc
Panajatovic, M. V., Singh, F., Krähenbühl, S. and Bouitbir, J. (2020) “Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression”, Biomedicines. MDPI AG, 8(9), p. 351. doi: 10.3390/biomedicines8090351.   edoc
Sanvee, G. M., Panajatovic, M., Bouitbir, D. J. and Krähenbühl, D. (2020) “Statins and Insulin Resistance”, European cardiology. Radcliffe Cardiology, 15, p. e44. doi: 10.15420/ecr.2020.15.1.PO21.   edoc
Schittny, A., Huwyler, J. and Puchkov, M. (2020) “Mechanisms of increased bioavailability through amorphous solid dispersions: a review”, Drug delivery. Taylor and Francis, 27(1), pp. 110–127. doi: 10.1080/10717544.2019.1704940.   edoc
Suenderhauf, C., Berger, B., Puchkov, M., Schmid, Y., Müller, S., Huwyler, J., Haschke, M., Krähenbühl, S. and Duthaler, U. (2020) “Pharmacokinetics and phenotyping properties of the ‘Basel’ phenotyping cocktail combination capsule in healthy male adults”, British journal of clinical pharmacology. Wiley, 86(2), pp. 352–361. doi: 10.1111/bcp.14157.   edoc
Häuser, C., Goldbach, P., Huwyler, J., Friess, W. and Allmendinger, A. (2020) “Excipients for Room Temperature Stable Freeze-Dried Monoclonal Antibody Formulations”, Journal of Pharmaceutical Sciences. Elsevier, 109(1), pp. 807–817. doi: 10.1016/j.xphs.2019.10.016.   edoc
Wagner-Hattler, L., Québatte, G., Keiser, J., Schoelkopf, J., Schlepütz, C. M., Huwyler, J. and Puchkov, M. (2020) “Study of drug particle distributions within mini-tables using synchrotron X-ray microtomography and superpixel image clustering”, International Journal of Pharmaceutics. Elsevier, 573, p. 118827. doi: 10.1016/j.ijpharm.2019.118827.   edoc
Dreckmann, T., Ludwig, I.-S., Boeuf, J., Lümkemann, J. and Huwyler, J. (2020) “Low Volume Aseptic Filling: Impact of Pump Systems on Shear Stress”, European Journal of Pharmaceutics and Biopharmaceutics. Elsevier, 147, pp. 10–18. doi: 10.1016/j.ejpb.2019.12.006.   edoc
Fischer, A., Sellner, M., Neranjan, S., Smiesko, M. and Lill, M. A. (2020) “Potential Inhibitors for Novel Coronavirus Protease Identified by Virtual Screening of 606 Million Compounds”, International journal of molecular sciences. MDPI, 21(10), p. 3626. doi: 10.3390/ijms21103626.   edoc | Open Access
Ehrsam, D., Sieber, S., Oufir, M., Porta, F., Hamburger, M., Huwyler, J. and Meyer zu Schwabedissen, H. E. (2020) “Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9”, Bioconjugate Chemistry. American Chemical Society, 31(3), pp. 781–793. doi: 10.1021/acs.bioconjchem.9b00865.   edoc
Mancuso, R. V., Casper, J., Schmidt, A. G., Krähenbühl, S. and Weitz-Schmidt, G. (2020) “Anti-αLβ2 antibodies reveal novel endocytotic cross-modulatory functionality”, British Journal of Pharmacology. Wiley, 177(12), pp. 2696–2711. doi: 10.1111/bph.14996.   edoc
Baas, I., Delvasto-Nuñez, L., Ligthart, P., Brouwer, C., Folman, C., Reis, E. S., Ricklin, D., Lambris, J. D., Wouters, D., de Haas, M., Jongerius, I. and Zeerleder, S. S. (2020) “Complement C3 inhibition by compstatin Cp40 prevents intra- and extravascular hemolysis of red blood cells”, Haematologica. Ferrata Storti Foundation, 105(2), pp. e57-e60. doi: 10.3324/haematol.2019.216028.   edoc | Open Access
Schneider, R., Reinau, D., Schur, N., Blozik, E., Früh, M., Signorell, A., Heininger, U., Schwenkglenks, M. and Meier, C. R. (2020) “Coverage rates and timeliness of nationally recommended vaccinations in Swiss preschool children: A descriptive analysis using claims data”, Vaccine. Elsevier, 38(6), pp. 1551–1558. doi: 10.1016/j.vaccine.2019.11.057.   edoc
Pironi, L., Boeykens, K., Bozzetti, F., Joly, F., Klek, S., Lal, S., Lichota, M., Mühlebach, S., Van Gossum, A., Wanten, G., Wheatley, C. and Bischoff, S. C. (2020) “ESPEN guideline on home parenteral nutrition”, Clinical Nutrition. Elsevier, 39(6), pp. 1645–1666. doi: 10.1016/j.clnu.2020.03.005.   edoc | Open Access

2019

Bromek, E., Rysz, M., Haduch, A. and Daniel, W. A. (2019) “Stimulation of 5-HT; 2C; serotonin receptor subtype in the hypothalamic arcuate nuclei (ARC) increases the cytochrome P450 activity in the liver”, Pharmacological Reports. Elsevier, 71(6), pp. 1210–1212. doi: 10.1016/j.pharep.2019.05.010.   edoc
Bromek, E., Rysz, M., Haduch, A. and Daniel, W. A. (2019) “Serotonin Receptors of 5-HT; 2; Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone-Releasing Hormone/Growth Hormone Hormonal Pathway”, Drug Metabolism and Disposition. American Society for Pharmacology and Experimental Therapeutics, 47(2), pp. 80–85. doi: 10.1124/dmd.118.083808.   edoc
Mühlebach, S., Aeberhard, C. and Stanga, Z. (2019) “6.1.4. Pharmaceutical aspects in enteral feeding and drugs”, in Sobotka, L. (ed.) Basics in Clinical Nutrition. Prague: Galén (ESPEN), pp. 314–319.   edoc
Frei, P., Silbermann, M., Mühlethaler, T., Jiang, X., Schwardt, O., Hevey, R. and Ernst, B. (2019) “Comparison of Affinity Ranking by Target-directed Dynamic Combinatorial Chemistry and Surface Plasmon Resonance”, Arkivoc. ARKAT USA, part iv, pp. 143–167. doi: 10.24820/ark.5550190.p010.913.   edoc
Mühlebach, S., Aeberhard, C., Driscoll, D. F., Hardy, G. and Stanga, Z. (2019) “6.2.3. Pharmaceutical aspects of parenteral nutrition support; 6.2.3.1 How to prepare parenteral nutrition (PN) admixtures, and the role and function of the pharmacist; 6.2.3.2. Stability and compatibility of parenteral nutrition; 6.2.3.3. Drugs and nutritional admixtures”, in Sobotka, L. (ed.) Basics in Clinical Nutrition. Prague: Galén (ESPEN), pp. 345–369.   edoc
Sych, J., Kaelin, I., Gerlach, F., Wróbel, A., Le, T., FitzGerald, R., Pestoni, G., Faeh, D., Krieger, J.-P. and Rohrmann, S. (2019) “Intake of Processed Meat and Association with Sociodemographic and Lifestyle Factors in a Representative Sample of the Swiss Population”, Nutrients. MDPI, 11(11), p. 2556. doi: 10.3390/nu11112556.   edoc
Oufir, M., Zabela, V., Hettich, T., Schlotterbeck, G., Wimmer, L., Mihovilovic, M. D., Guillet, F., Bouaita, B., Shevchenko, B. and Hamburger, M. (2019) “Piperine analogs as modulators of the central nervous system”, Chimia. Swiss Chemical Society , 73(3), p. 206. doi: 10.2533/chimia.2019.206.   edoc
Sauer, M. M., Jakob, R. P., Luber, T., Canonica, F., Navarra, G., Ernst, B., Unverzagt, C., Maier, T. and Glockshuber, R. (2019) “Binding of the bacterial adhesin FimH to its natural, multivalent high-mannose type glycan targets”, Journal of the American Chemical Society. American Chemical Society, 141(2), pp. 936–944. doi: 10.1021/jacs.8b10736.   edoc
Bleher, S., Buck, J., Muhl, C., Sieber, S., Barnert, S., Witzigmann, D., Huwyler, J., Braz, M. and Süss, R. (2019) “Poly(Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes”, Small. Wiley, 15(50), p. 1904716. doi: 10.1002/smll.201904716.   edoc
Zhou, X., Luethi, D., Sanvee, G. M., Bouitbir, J., Liechti, M. E. and Krähenbühl, S. (2019) “Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts”, International journal of molecular sciences. Multidisciplinary Digital Publishing Institute, 20(7), p. 1561. doi: 10.3390/ijms20071561.   edoc
Bühler, T., Medinger, M., Bouitbir, J., Krähenbühl, S. and Leuppi-Taegtmeyer, A. (2019) “Hepatotoxicity Due to Azole Antimycotic Agents in a HLA B*35:02-Positive Patient”, Frontiers in pharmacology. Frontiers Media, 10, p. 645. doi: 10.3389/fphar.2019.00645.   edoc
Bouitbir, J., Alshaikhali, A., Panajatovic, M. V., Abegg, V. F., Paech, F. and Krähenbühl, S. (2019) “Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts ”, Toxicology. Elsevier, 426, p. 152281. doi: 10.1016/j.tox.2019.152281.   edoc
Sedighi, M., Sieber, S., Rahimi, F., Shahbazi, M.-A., Rezayan, A. H., Huwyler, J. and Witzigmann, D. (2019) “Rapid optimization of liposome characteristics using a combined microfluidics and design-of-experiment approach”, Drug delivery and translational research. Springer, 9(1), pp. 404–413. doi: 10.1007/s13346-018-0587-4.   edoc
van Griensven, M., Ricklin, D., Denk, S., Halbgebauer, R., Braun, C. K., Schultze, A., Hönes, F., Koutsogiannaki, S., Primikyri, A., Reis, E., Messerer, D., Hafner, S., Radermacher, P., Biglarnia, A.-R., Resuello, R. R. G., Tuplano, J. V., Mayer, B., Nilsson, K., Nilsson, B., Lambris, J. D. and Huber-Lang, M. (2019) “Protective Effects of the Complement Inhibitor Compstatin CP40 in Hemorrhagic Shock”, Shock. Lippincott, Williams & Wilkins, 51(1), pp. 78–87. doi: 10.1097/SHK.0000000000001127.   edoc
Mastellos, D. C., Blom, A. M., Connolly, E. S., Daha, M. R., Geisbrecht, B. V., Ghebrehiwet, B., Gros, P., Hajishengallis, G., Holers, V. M., Huber-Lang, M., Kinoshita, T., Mollnes, T. E., Montgomery, R. A., Morgan, B. P., Nilsson, B., Pio, R., Ricklin, D., Risitano, A. M., Taylor, R. P., Mantovani, A., Ioannidis, J. P. A. and Lambris, J. D. (2019) “’Stealth’ corporate innovation: an emerging threat for therapeutic drug development”, Nature immunology, 20(11), pp. 1409–1413. doi: 10.1038/s41590-019-0503-1.   edoc
Mastellos, D. C., Ricklin, D. and Lambris, J. D. (2019) “Clinical promise of next-generation complement therapeutics”, Nature reviews. Drug discovery, 18(9), pp. 707–729. doi: 10.1038/s41573-019-0031-6.   edoc
Lombardi, E., Matte, A., Risitano, A. M., Ricklin, D., Lambris, J. D., De Zanet, D., Jokiranta, S. T., Martinelli, N., Scambi, C., Salvagno, G., Bisoffi, Z., Colato, C., Siciliano, A., Bortolami, O., Mazzuccato, M., Zorzi, F., De Marco, L. and De Franceschi, L. (2019) “Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule”, Haematologica, 104(5), pp. 919–928. doi: 10.3324/haematol.2018.198622.   edoc
Häuser, C., Goldbach, P., Huwyler, J., Fiess, W. and Allmendinger, A. (2019) “Be Aggressive! Amorphous Excipients Enabling Single-Step Freeze-Drying of Monoclonal Antibody Formulations”, Pharmaceutics. MDPI, 11(11), p. 616. doi: 10.3390/pharmaceutics11110616.   edoc
Sanvee, G. M., Bouitbir, J. and Krähenbühl, S. (2019) “Insulin prevents and reverts simvastatin-induced toxicity in C2C12 skeletal muscle cells”, Scientific reports. Nature Publishing Group, 9(1), p. 7409. doi: 10.1038/s41598-019-43938-5.   edoc
Sanvee, G. M., Panajatovic, M. V., Bouitbir, J. and Krähenbühl, S. (2019) “Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle”, Biochemical pharmacology. Elsevier, 164, pp. 23–33. doi: 10.1016/j.bcp.2019.02.025.   edoc
Singh, F., Zoll, J., Duthaler, U., Charles, A.-L., Panajatovic, M. V., Laverny, G., McWilliams, T. G., Metzger, D., Geny, B., Krähenbühl, S. and Bouitbir, J. (2019) “PGC-1β modulates statin-associated myotoxicity in mice”, Archives of Toxicology. Springer, 93(2), pp. 487–504. doi: 10.1007/s00204-018-2369-7.   edoc
Bouitbir, J., Sanvee, G. M., Panajatovic, M. V., Singh, F. and Krähenbühl, S. (2019) “Mechanisms of statin-associated skeletal muscle-associated symptoms”, Pharmacological research. Elsevier, (154), p. 104201. doi: 10.1016/j.phrs.2019.03.010.   edoc
Reber, E., Messerli, M., Stanga, Z. and Mühlebach, S. (2019) “Pharmaceutical Aspects of Artificial Nutrition”, Journal of clinical medicine, 8(11), p. jcm8112017. doi: 10.3390/jcm8112017.   edoc
Dias, C., Matos, A. M., Blasquez-Sanchez, M. T., Calado, P., Martins, A., Daetwyler, P., Ernst, B., Macedo, M. P., Colabufo, N. and Rauter, A. (2019) “2-Deoxyglycosylation towards more effective and bioavailable neuroprotective molecules inspired by nature”, Pure and applied chemistry. de Gruyter, 91(7), pp. 1209–1221. doi: 10.1515/pac-2019-0303.   edoc
Santos, S., Haslinger, C., Mennet, M., von Mandach, U., Hamburger, M. and Simões-Wüst, A. P. (2019) “Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study”, BMC Complem. Altern. Med, 19, p. 292. doi: 10.1186/s12906-019-2711-5.   edoc | Open Access
Flühmann, B., Ntai, I., Borchard, G., Simoens, S. and Mühlebach, S. (2019) “Nanomedicines: The magic bullets reaching their target?”, European journal of pharmaceutical sciences. Elsevier, 128, pp. 73–80. doi: 10.1016/j.ejps.2018.11.019.   edoc
Mühlebach , S. F. (2019) “Diets and Diet Therapy: Parenteral Nutrition”, Encyclopedia of Food Security and Sustainability (FOSS). Elsevier, 2, pp. 131–142. doi: 10.1016/B978-0-08-100596-5.21937-9.   edoc
Malagnino, V., Hussner, J., Issa, A., Midzic, A. and Meyer zu Schwabedissen, H. E. (2019) “OATP1B3-1B7 a novel Organic Anion Transporting Polypeptide is modulated by FXR ligands and transports bile acids”, American journal of physiology. Gastrointestinal and liver physiology, 316(6), pp. G751-G762. doi: 10.1152/ajpgi.00330.2018.   edoc
Cramer, J., Sager, C. P. and Ernst, B. (2019) “Hydroxyl Groups in Synthetic and Natural-Product-Derived Therapeutics: A Perspective on a Common Functional Group”, Journal of medicinal chemistry, 62(20), pp. 8915–8930. doi: 10.1021/acs.jmedchem.9b00179.   edoc
Mertenat, D., Dal Cero, M., Vogl, C. R., Ivemeyer, S., Meier, B., Maeschli, A., Hamburger, M. and Walkenhorst, M. (2019) “Ethnoveterinary knowledge of farmers in bilingual regions of Switzerland - is there potential to extend veterinary options to reduce antimicrobial use?”, Journal of ethnopharmacology. Elsevier Science, 246, p. 112184. doi: 10.1016/j.jep.2019.112184.   edoc
Reinhardt, J. K., Klemd, A. M., Danton, O., De Mieri, M., Smiesko, M., Huber, R. ., Bürgisser, T., Gründemann, C. and Hamburger, M. (2019) “Sesquiterpene lactones from Artemisia argyi - absolute configuration and immunosuppressive activity”, Journal of Natural Products. American Chemical Society, 82(6), pp. 1424–1433. doi: 10.1021/acs.jnatprod.8b00791.   edoc
Fischer, A. and Smieško, M. (2019) “Spontaneous Ligand Access Events to Membrane-Bound Cytochrome P450 2D6 Sampled at Atomic Resolution”, Scientific reports, 9(1), p. 16411. doi: 10.1038/s41598-019-52681-w.   edoc
Fischer, A. and Smieško, M. (2019) “Ligand Pathways in Nuclear Receptors”, Journal of chemical information and modeling, 59(7), pp. 3100–3109. doi: 10.1021/acs.jcim.9b00360.   edoc
Beilmann, M., Boonen, H., Czich, A., Dear, G., Hewitt, P., Mow, T., Newham, P., Oinonen, T., Pognan, F., Roth, A., Valentin, J.-P., Van Goethem, F., Weaver, R. J., Birk, B., Boyer, S., Caloni, F., Chen, A. E., Corvi, R., Cronin, M. T. D., Daneshian, M., Ewart, L. C., Fitzgerald, R. E., Hamilton, G. A., Hartung, T., Kangas, J. D., Kramer, N. I., Leist, M., Marx, U., Polak, S., Rovida, C., Testai, E., Van der Water, B., Vulto, P. and Steger-Hartmann, T. (2019) “Optimizing drug discovery by Investigative Toxicology: Current and future trends”, ALTEX, 36(2), pp. 289–313. doi: 10.14573/altex.1808181.   edoc
de Matos, A. M., Martins, A., Man, T., Evans, D., Walter, M., Oliveira, M. C., López, Óscar, Fernandez-Bolaños, J. G., Dätwyler, P., Ernst, B., Macedo, M. P., Contino, M., Colabufo, N. A. and Rauter, A. P. (2019) “Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H; 2; O; 2; - and Aβ; 1-42; -Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells”, Pharmaceuticals (Basel, Switzerland), 12(2), p. 98. doi: 10.3390/ph12020098.   edoc
Faleschini, M. T., Maier, A., Fankhauser, S., Thasis, K., Hebeisen, S., Butterweck, V. and Hamburger, M. (2019) “Discovery of GABAA receptor modulators of natural origin - Validation of a FLIPR assay for screening and HPLC-based activity profiling”, Planta Medica. Georg Thieme Verlag, 85(18), p. 1586. doi: 10.1055/s-0039-3400027.   edoc
Kahnamoei, M. B., Tabefam, M., Ebrahimi, S. N., Danton, O., Hamburger, M. and Farimani, M. M. (2019) “Chemical constituents from the ethyl acetate extract of Salvia hydrangea DC. ex Benth”, Natural Product Communications. Natural Product, 14(6), p. 1934578X1984885. doi: 10.1177/1934578X19848852 .   edoc
Roel-Touris, J., Don, C. G., Vargas Honorato, R., Rodrigues, J. P. G. L. M. and Bonvin, A. M. J. J. (2019) “Less is more: Coarse-grained integrative modeling of large biomolecular assemblies with HADDOCK”, Journal of chemical theory and computation. American Chemical Society, 15(11), pp. 6358–6367. doi: 10.1021/acs.jctc.9b00310.   edoc
Ehrsam, D., Porta, F., Hussner, J., Seibert, I. and Meyer Zu Schwabedissen, H. E. (2019) “PDMS-PMOXA-Nanoparticles Featuring a Cathepsin B-Triggered Release Mechanism”, Materials. MDPI, 12(17), p. 2836. doi: 10.3390/ma12172836.   edoc
Hevey, R. (2019) “Bioisosteres of Carbohydrate Functional Groups in Glycomimetic Design”, Biomimetics. MDPI AG, 4(3), p. 53. doi: 10.3390/biomimetics4030053.   edoc

2018

Rabbani, S., Fiege, B., Eris, D., Silbermann, M., Jakob, R. P., Navarra, G., Maier, T. and Ernst, B. (2018) “Conformational Switch of the Bacterial Adhesin FimH in the Absence of the Regulatory Domain: Engineering a Minimalistic Allosteric System”, Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 293(5), pp. 1835–1849. doi: 10.1074/jbc.M117.802942.   edoc
Ditter, D., Nieto, A., Mahler, H.-C., Roehl, H., Wahl, M., Huwyler, J. and Allmendinger, A. (2018) “Evaluation of Glass Delamination Risk in Pharmaceutical 10 mL/10R Vials”, Journal of Pharmaceutical Sciences, 107(2), pp. 624–637. doi: 10.1016/j.xphs.2017.09.016.   edoc
Haduch, A., Rysz, M., Papp, M. and Daniel, W. A. (2018) “The activity of brain and liver cytochrome P450 2D (CYP2D) is differently affected by antidepressants in the chronic mild stress (CMS) model of depression in the rat”, Biochemical Pharmacology. Elsevier, 156, pp. 398–405. doi: 10.1016/j.bcp.2018.09.005.   edoc
Bromek, E., Rysz, M., Haduch, A., Wójcikowski, J. and Daniel, W. A. (2018) “Activation of 5-HT; 1A; Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver”, Drug metabolism and disposition: the biological fate of chemicals, 46(6), pp. 786–793. doi: 10.1124/dmd.117.079632.   edoc
Baburin, I., Varkevisser, R., Schramm, A., Saxena, P., Beyl, S., Szkokan, P., Linder, T., Stary-Weinzinger, A., van der Heyden, M. A. G., Houtman, M., Takanari, H., Jonsson, M., Beekman, J. H. D., Hamburger, M., Vos, M. A. and Hering, S. (2018) “Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo”, Pharmacological Research. Elsevier, 131, pp. 150–163. doi: 10.1016/j.phrs.2018.02.024.   edoc
Pottecher, J., Adamopoulos, C., Lejay, A., Bouitbir, J., Charles, A.-L., Meyer, A., Singer, M., Wolff, V., Diemunsch, P., Laverny, G., Metzger, D. and Geny, B. (2018) “Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?”, Frontiers in Physiology. Frontiers Media, 9, p. 579. doi: 10.3389/fphys.2018.00579.   edoc
Fritsche, E., Grandjean, P., Crofton, K. M., Aschner, M., Goldberg, A., Heinonen, T., Hessel, E. V. S., Hogberg, H. T., Bennekou, S. H., Lein, P. J., Leist, M., Mundy, W. R., Paparella, M., Piersma, A. H., Sachana, M., Schmuck, G., Solecki, R., Terron, A., Monnet-Tschudi, F., Wilks, M. F., Witters, H., Zurich, M.-G. and Bal-Price, A. (2018) “Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes”, Toxicology and applied pharmacology. Academic Press, 354, pp. 3–6. doi: 10.1016/j.taap.2018.02.004.   edoc
Gawarammana, I., Buckley, N. A., Mohamed, F., Naser, K., Jeganathan, K., Ariyananada, P. L., Wunnapuk, K., Dobbins, T. A., Tomenson, J. A., Wilks, M. F., Eddleston, M. and Dawson, A. H. (2018) “High-dose immunosuppression to prevent death after paraquat self-poisoning - a randomised controlled trial”, Clinical toxicology. Taylor and Francis, 56(7), pp. 633–639. doi: 10.1080/15563650.2017.1394465.   edoc
Thuerig, B., Ramseyer, J., Hamburger, M., Ludwig, M., Oberhänsli, T., Potterat, O., Schärer, H.-J. and Tamm, L. (2018) “Efficacy of a Magnolia officinalis bark extract against grapevine downy mildew and apple scab under controlled and field conditions”, Crop Protection. Elsevier, 114, pp. 97–105. doi: 10.1016/j.cropro.2018.08.011.   edoc
Yokoyama, R., Kimura, G., Schlepütz, C. M., Huwyler, J. and Puchkov, M. (2018) “Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces”, Pharmaceutics. MDPI, 10(4), p. 259. doi: 10.3390/pharmaceutics10040259.   edoc | Open Access
Bahadori, M. B., Eskandani, M., De Mieri, M., Hamburger, M. and Nazemiyeh, H. (2018) “Anti-proliferative activity-guided isolation of clerodermic acid from Salvia nemorosa L.: Geno/cytotoxicity and hypoxia-mediated mechanism of action”, Food and chemical toxicology. Elsevier, 120, pp. 155–163. doi: 10.1016/j.fct.2018.06.060.   edoc
Farimani, M. M., Khodaei, B., Moradi, H., Aliabadi, A., Ebrahimi, S. N., De Mieri, M., Kaiser, M. and Hamburger, M. (2018) “Phytochemical study of Salvia leeriifolia roots: rearranged abietane diterpenoids with antiprotozoal activity”, Journal of Natural Products. American Chemical Society, 81(6), pp. 1384–1390. doi: 10.1021/acs.jnatprod.7b01019.   edoc
Tabefam, M., Moridi Farimani, M., Danton, O., Ramseyer, J., Kaiser, M., Ebrahimi, S. N., Salehi, P., Batooli, H., Potterat, O. and Hamburger, M. (2018) “Antiprotozoal diterpenes from Perovskia abrotanoides”, Planta Medica. Georg Thieme , 84(12-13), pp. 913–919. doi: 10.1055/a-0608-4946.   edoc
Sedighi, M., Rahimi, F., Rezayan, A. H., Shahbazi, M.-A., Witzigmann, D. and Huwyler, J. (2018) “Combined cerium oxide nanocapping and layer-by-layer coating of porous silicon containers for controlled drug release”, Journal of Materials Science. Springer, 53, pp. 14975–14988. doi: 10.1007/s10853-018-2731-4.   edoc
Campbell, F., Bos, F. L., Sieber, S., Arias-Alpizar, G., Koch, B. E., Huwyler, J., Kros, A. and Bussmann, J. (2018) “Directing Nanoparticle Biodistribution through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake”, ACS Nano. American Chemical Society, 12(3), pp. 2138–2150. doi: 10.1021/acsnano.7b06995.   edoc
Mingard, C., Paech, F., Bouitbir, J. and Krähenbühl, S. (2018) “Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines”, Journal of applied toxicology : JAT. John Wiley And Sons, 38(3), pp. 418–431. doi: 10.1002/jat.3551.   edoc
Paech, F., Mingard, C., Grünig, D., Abegg, V. F., Bouitbir, J. and Krähenbühl, S. (2018) “Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells”, Toxicology. Elsevier, 395, pp. 34–44. doi: 10.1016/j.tox.2018.01.005.   edoc
Paech, F., Abegg, V. F., Duthaler, U., Terracciano, L., Bouitbir, J. and Krähenbühl, S. (2018) “Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice”, Toxicology. Elsevier, 409, pp. 13–23. doi: 10.1016/j.tox.2018.07.009.   edoc
Bal-Price, A., Crofton, K. M., Leist, M., Allen, S., Arand, M., Buetler, T., Delrue, N., FitzGerald, R. E., Hartung, T., Heinonen, T., Hogberg, H., Bennekou, S. H., Lichtensteiger, W., Oggier, D., Paparella, M., Axelstad, M., Piersma, A., Rached, E., Schilter, B., Schmuck, G., Stoppini, L., Tongiorgi, E., Tiramani, M., Monnet-Tschudi, F., Wilks, M. F., Ylikomi, T. and Fritsche, E. (2018) “International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes”, Archives of Toxicology. Springer, 89(2), pp. 269–287. doi: 10.1007/s00204-015-1464-2.   edoc
Bal-Price, A., Hogberg, H. T., Crofton, K. M., Daneshian, M., FitzGerald, R. E., Fritsche, E., Heinonen, T., Hougaard Bennekou, S., Klima, S., Piersma, A. H., Sachana, M., Shafer, T. J., Terron, A., Monnet-Tschudi, F., Viviani, B., Waldmann, T., Westerink, R. H. S., Wilks, M. F., Witters, H., Zurich, M.-G. and Leist, M. (2018) “Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity”, ALTEX. Springer Spektrum, 35(3), pp. 306–352. doi: 10.14573/altex.1712081.   edoc
Sanvido, O., Schmid, K., FitzGerald, R. E., Roth, N., Wilks, M. F., Bormann, P. and Hopf, N. B. (2018) “A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models”, Regulatory toxicology and pharmacology. Elsevier, 98, pp. 171–183. doi: 10.1016/j.yrtph.2018.07.022.   edoc
Mühlebach, S., Haudenschild, U. and Schäublin, M. (2018) “Supply diruptions of essential drugs: a reporting platform based on a public-private-partnership to prevent and overcome shortages in Switzerland”, Die pharmazeutische Industrie. Editio Cantor , 50(5), pp. 594–601.   edoc
Hersberger, K. E. (2018) “Part VI Pharmaceutical Care for Specific Patient Groups ”, The Pharmacist Guide to Implementing Pharmaceutical Care. Springer, pp. 295–296. Available at: https://link.springer.com/content/pdf/bfm%3A978-3-319-92576-9%2F6%2F1.pdf.   edoc
Danton, O., Alexander, L., Hunlun, C., de Beer, D., Hamburger, M. and Joubert, E. (2018) “Bitter taste impact and thermal conversion of a naringenin glycoside isolated from Cyclopia genistoides”, Journal of natural products. American Society of Pharmacognosy, 81(12), pp. 2743–2749. doi: 10.1021/acs.jnatprod.8b00710.   edoc
Don, C. G. and Smieško, M. (2018) “Out-compute drug side effects: Focus on cytochrome P450 2D6 modeling”, Wiley interdisciplinary reviews; computational molecular science. Wiley, 8(5), p. e1366. doi: 10.1002/wcms.1366.   edoc
Smieško, M., Don, C. G., Meuwly, R., Kucsera, S. and Brüschweiler, B. J. (2018) “Large-scale in silico screening of compounds contained in printing inks for food packaging materials”, Toxicology Letters. Elsevier, 295, p. S96. doi: 10.1016/j.toxlet.2018.06.594.   edoc
Wimmersberger, D., Coulibaly, J. T., Schulz, J. D., Puchkov, M., Huwyler, J., N’Gbesso, Y., Hattendorf, J. and Keiser, J. (2018) “Efficacy and Safety of Ivermectin Against Trichuris trichiura in Preschool-aged and School-aged Children: A Randomized Controlled Dose-finding Trial”, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 67(8), pp. 1247–1255. doi: 10.1093/cid/ciy246.   edoc
Mohebbi, M., Bararjanian, M., Ebrahimi, S. N., Smiesko, M. and Salehi, P. (2018) “Noscapine Derivatives as New Chiral Catalysts in Asymmetric Synthesis: Highly Enantioselective Addition of Diethylzinc to Aldehydes”, SYNTHESIS-STUTTGART. GEORG THIEME VERLAG KG, 50(9), pp. 1841–1848. doi: 10.1055/s-0037-1609224.   edoc
Malagnino, V., Hussner, J., Seibert, I., Stolzenburg, A., Sager, C. P. and Meyer zu Schwabedissen, H. E. (2018) “LST-3TM12 is a member of the OATP1B family and a functional transporter”, Biochemical pharmacology, 148, pp. 75–87. doi: 10.1016/j.bcp.2017.12.012.   edoc
Yuan, X., Yang, M., Chen, X., Zhang, X., Sukhadia, S., Musolino, N., Bao, H., Chen, T., Xu, C., Wang, Q., Santoro, S., Ricklin, D., Hu, J., Lin, R., Yang, W., Li, Z., Qin, W., Zhao, A., Scholler, N. and Coukos, G. (2018) “Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy”, Cancer immunology, immunotherapy : CII, 67(2), pp. 329–339. doi: 10.1007/s00262-017-2101-0.   edoc
Ditter, D., Mahler, H.-C., Gohlke, L., Nieto, A., Roehl, H., Huwyler, J., Wahl, M. and Allmendinger, A. (2018) “Impact of Vial Washing and Depyrogenation on Surface Properties and Delamination Risk of Glass Vials”, Pharmaceutical research, 35(7), p. 146. doi: 10.1007/s11095-018-2421-6.   edoc
Boll, B., Josse, L., Heubach, A., Hochenauer, S., Finkler, C., Huwyler, J. and Koulov, A. V. (2018) “Impact of non-ideal analyte behavior on the separation of protein aggregates by asymmetric flow field-flow fractionation”, Journal of Separation Science, 2018; 41, pp. 2854–2864. doi: 10.1002/jssc.201701457.   edoc
Zihlmann, P., Silbermann, M., Sharpe, T., Jiang, X., Mühlethaler, T., Jakob, R. P., Rabbani, S., Sager, C. P., Frei, P., Pang, L., Maier, T. and Ernst, B. (2018) “KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists ”, Chemistry (Weinheim an der Bergstrasse, Germany), 24, pp. 1–10. doi: 10.1002/chem.201802599.   edoc
Siegrist, S., Cörek, E., Detampel, P., Sandström, J., Wick, P. and Huwyler, J. (2018) “Preclinical hazard evaluation strategy for nanomedicines”, Nanotoxicology, pp. 1–27. doi: 10.1080/17435390.2018.1505000.   edoc
Fischer, A., Don, C. G. and Smieško, M. (2018) “Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6”, Journal of chemical information and modeling. American Chemical Society, 58(9), pp. 1962–1975. doi: 10.1021/acs.jcim.8b00080.   edoc
Sánchez-Corral, P., Pouw, R. B., López-Trascasa, M. and Józsi, M. (2018) “Self-Damage Caused by Dysregulation of the Complement Alternative Pathway: Relevance of the Factor H Protein Family”, Frontiers in immunology, 9, p. 1607. doi: 10.3389/fimmu.2018.01607.   edoc
Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Schultheiss, U. T., Traglia, M., Ahluwalia, T. S., Akiyama, M., Appel, E. V. R., Arking, D. E., Arnold, A., Astrup, A., Beekman, M., Beilby, J. P., Bekaert, S., Boerwinkle, E., Brown, S. J., De Buyzere, M., Campbell, P. J., Ceresini, G., Cerqueira, C., Cucca, F., Deary, I. J., Deelen, J., Eckardt, K.-U., Ekici, A. B., Eriksson, J. G., Ferrrucci, L., Fiers, T., Fiorillo, E., Ford, I., Fox, C. S., Fuchsberger, C., Galesloot, T. E., Gieger, C., Gögele, M., De Grandi, A., Grarup, N., Greiser, K. H., Haljas, K., Hansen, T., Harris, S. E., van Heemst, D., den Heijer, M., Hicks, A. A., den Hollander, W., Homuth, G., Hui, J., Ikram, M. A., Ittermann, T., Jensen, R. A., Jing, J., Jukema, J. W., Kajantie, E., Kamatani, Y., Kasbohm, E., Kaufman, J.-M., Kiemeney, L. A., Kloppenburg, M., Kronenberg, F., Kubo, M., Lahti, J., Lapauw, B., Li, S., Liewald, D. C. M., Lifelines Cohort Study, Lim, E. M., Linneberg, A., Marina, M., Mascalzoni, D., Matsuda, K., Medenwald, D., Meisinger, C., Meulenbelt, I., De Meyer, T., Meyer Zu Schwabedissen, H. E., Mikolajczyk, R., Moed, M., Netea-Maier, R. T., Nolte, I. M., Okada, Y., Pala, M., Pattaro, C., Pedersen, O., Petersmann, A., Porcu, E., Postmus, I., Pramstaller, P. P., Psaty, B. M., Ramos, Y. F. M., Rawal, R., Redmond, P., Richards, J. B., Rietzschel, E. R., Rivadeneira, F., Roef, G., Rotter, J. I., Sala, C. F., Schlessinger, D., Selvin, E., Slagboom, P. E., Soranzo, N., Sørensen, T. I. A., Spector, T. D., Starr, J. M., Stott, D. J., Taes, Y., Taliun, D., Tanaka, T., Thuesen, B., Tiller, D., Toniolo, D., Uitterlinden, A. G., Visser, W. E., Walsh, J. P., Wilson, S. G., Wolffenbuttel, B. H. R., Yang, Q., Zheng, H.-F., Cappola, A., Peeters, R. P., Naitza, S., Völzke, H., Sanna, S., Köttgen, A., Visser, T. J. and Medici, M. (2018) “Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation”, Nature communications, 9(1), p. 4455. doi: 10.1038/s41467-018-06356-1.   edoc
Haeuser, C., Goldbach, P., Huwyler, J., Friess, W. and Allmendinger, A. (2018) “Imaging Techniques to Characterize Cake Appearance of Freeze-Dried Products”, Journal of pharmaceutical sciences, 107(11), pp. 2810–2822. doi: 10.1016/j.xphs.2018.06.025.   edoc
Wagner-Hattler, L., Schoelkopf, J., Huwyler, J. and Puchkov, M. (2018) “Stability investigation of FCC-based tablets for oral suspension with caffeine and oxantel pamoate as model drugs”, Drug development and industrial pharmacy, pp. 1–9. doi: 10.1080/03639045.2018.1529784.   edoc
Arnet, I., Greenland, M., Knuiman, M. W., Rankin, J. M., Hung, J., Nedkoff, L., Briffa, T. G. and Sanfilippo, F. M. (2018) “Operationalization and validation of a novel method to calculate adherence to polypharmacy with refill data from the Australian pharmaceutical benefits scheme (PBS) database”, Clinical Epidemiology, 10, pp. 1181–1194. doi: 10.2147/CLEP.S153496.   edoc

2017

Widmer, N., Schumacher, L., Meister, T., Krähenbühl, J.-M., Mühlebach, S. and Bonnabry, P. (2017) “Notfall- und Katastrophenpharmazie: Neues Schweizer Fachzentrum”, PharmaJournal. Schweizer Apothekerzeitung. PharmaSuisse, 155(15), pp. 14–17.   edoc | Open Access
Fritsche, E., Crofton, K. M., Hernandez, A. F., Hougaard Bennekou, S., Leist, M., Bal-Price, A., Reaves, E., Wilks, M. F., Terron, A., Solecki, R., Sachana, M. and Gourmelon, A. (2017) “OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes”, ALTEX. Springer Spektrum, 34(2), pp. 311–315. doi: 10.14573/altex.1701171.   edoc
Mamoulakis, C., Tsarouhas, K., Fragkiadoulaki, I., Heretis, I., Wilks, M. F., Spandidos, D. A., Tsitsimpikou, C. and Tsatsakis, A. (2017) “Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies”, Pharmacology & therapeutics. Elsevier, 180, pp. 99–112. doi: 10.1016/j.pharmthera.2017.06.009.   edoc
Haegler, P., Grünig, D., Berger, B., Terracciano, L., Krähenbühl, S. and Bouitbir, J. (2017) “Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice”, PLoS One. Public Library Science, 12(1), p. e0171026. doi: 10.1371/journal.pone.0171026.   edoc
Charles, A.-L., Guilbert, A.-S., Guillot, M., Talha, S., Lejay, A., Meyer, A., Kindo, M., Wolff, V., Bouitbir, J., Zoll, J. and Geny, B. (2017) “Muscles Susceptibility to Ischemia-Reperfusion Injuries Depends on Fiber Type Specific Antioxidant Level”, Frontiers in physiology. Frontiers Media, 8, p. 52. doi: 10.3389/fphys.2017.00052.   edoc
Hartung, T., FitzGerald, R. E., Jennings, P., Mirams, G. R., Peitsch, M. C., Rostami-Hodjegan, A., Shah, I., Wilks, M. F. and Sturla, S. J. (2017) “Systems Toxicology: Real World Applications and Opportunities”, Chemical research in toxicology. American Chemical Society (ACS) , 30(4), pp. 870–882. doi: 10.1021/acs.chemrestox.7b00003.   edoc | Open Access
Brueckner, D., Krähenbühl, S., Zuber, U., Bonkat, G. and Braissant, O. (2017) “An alternative sterility assessment for parenteral drug products using isothermal microcalorimetry”, Journal of Applied Microbiology, 123(3), pp. 773–779. doi: 10.1111/jam.13520.   edoc
Krähenbühl, S. and Pichler, W. J. (2017) “Medikamentöse Hepatopathien - Drug-induced liver injury”, Therapeutische Umschau. Hogrefe, 74(3), pp. 123–130. doi: 10.1024/0040-5930/a000895.   edoc
Paech, F., Bouitbir, J. and Krähenbühl, S. (2017) “Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis”, Frontiers in Pharmacology. Frontiers Media, 8, p. 367. doi: 10.3389/fphar.2017.00367.   edoc
Barda, B., Sayasone, S., Phongluxa, K., Xayavong, S., Keoduangsy, K., Odermatt, P., Puchkov, M., Huwyler, J., Hattendorf, J. and Keiser, J. (2017) “Efficacy of Moxidectin Versus Ivermectin Against Strongyloides stercoralis Infections: A Randomized, Controlled Noninferiority Trial”, Clinical Infectious Diseases. Oxford University Press, 65(2), pp. 276–281. doi: 10.1093/cid/cix278.   edoc
Krähenbühl, S. (2017) “Importance of the skeletal muscle carnitine stores in fuel selection”, The Journal of Physiology. Wiley, 595(17), pp. 5727–5728. doi: 10.1113/JP274755.   edoc
Blaser, L., Hassna, H., Hofmann, S., Holbro, A., Haschke, M., Rätz Bravo, A., Zeller, A., Krähenbühl, S. and Taegtmeyer, A. (2017) “Leucopenia associated with metamizole: a case-control study”, Swiss medical weekly. EMH Swiss Medical Publishers, 147, p. w14438. doi: 10.4414/smw.2017.14438.   edoc
Brueckner, D., Solokhina, A., Krähenbühl, S. and Braissant, O. (2017) “A combined application of tunable diode laser absorption spectroscopy and isothermal micro-calorimetry for calorespirometric analysis”, Journal of Microbiological Methods. Elsevier, 139, pp. 210–214. doi: 10.1016/j.mimet.2017.06.012.   edoc
Drago, S., Imboden, R., Schlatter, P., Buylaert, M., Krähenbühl, S. and Drewe, J. (2017) “Pharmacokinetics of Transdermal Etofenamate and Diclofenac in Healthy Volunteers”, Basic and Clinical Pharmacology and Toxicology. Wiley, 121(5), pp. 423–429. doi: 10.1111/bcpt.12818.   edoc
Grünig, D., Felser, A., Bouitbir, J. and Krähenbühl, S. (2017) “The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells”, Toxicology in Vitro. Elsevier, 42, pp. 337–347. doi: 10.1016/j.tiv.2017.05.013.   edoc
Paech, F., Messner, S., Spickermann, J., Wind, M., Schmitt-Hoffmann, A.-H., Witschi, A. T., Howell, B. A., Church, R. J., Woodhead, J., Engelhardt, M., Krähenbühl, S. and Maurer, M. (2017) “Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072”, Archives of Toxicology. Springer, 91(11), pp. 3647–3662. doi: 10.1007/s00204-017-1994-x.   edoc
Haegler, P., Joerin, L., Krähenbühl, S. and Bouitbir, J. (2017) “Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents”, Toxicological sciences. Oxford University Press, 157(1), pp. 183–195. doi: 10.1093/toxsci/kfx029.   edoc
Brueckner, D., Roesti, D., Zuber, U., Sacher, M., Duncan, D., Krähenbühl, S. and Braissant, O. (2017) “Tunable diode laser absorption spectroscopy as method of choice for non-invasive and automated detection of microbial growth in media fills”, Talanta. Elsevier, 167, pp. 21–29. doi: 10.1016/j.talanta.2017.01.088.   edoc
Randazzo, G. M., Tonoli, D., Strajhar, P., Xenarios, I., Odermatt, A., Boccard, J. and Rudaz, S. (2017) “Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study”, Journal of Chromatography B. Elsevier, 1071, pp. 11–18. doi: 10.1016/j.jchromb.2017.04.032.   edoc
Jiménez-Canino, R., Lorenzo-Díaz, F., Odermatt, A., Bailey, M. A., Livingstone, D. E. W., Jaisser, F., Farman, N. and Alvarez de la Rosa, D. (2017) “11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation”, Endocrinology. Oxford University Press, 158(11), pp. 4047–4063. doi: 10.1210/en.2017-00440.   edoc
Brecht, K., Riebel, V., Couttet, P., Paech, F., Wolf, A., Chibout, S.-D., Pognan, F., Krähenbühl, S. and Uteng, M. (2017) “Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin”, Toxicology in Vitro. Elsevier, 40, pp. 55–65. doi: 10.1016/j.tiv.2016.12.001.   edoc
Aeberhard , C. and Mühlebach, S. (2017) “Parenterale Ernährung - Grundlagen und Durchführung (Parenteral nutrition - basics and good practice)”, Aktuelle Ernährungsmedizin, 42(1), pp. 53–76. doi: 10.1055/s-0042-121786.   edoc
Astier, A., Barton Pai, A., Bissig, M., Crommelin, D. J. A., Flühmann, B., Hecq, J.-D., Knoeff, J., Lipp, H.-P., Morell-Baladrón, A. and Mühlebach, S. (2017) “How to select a nanosimilar”, Annals of the New York Academy of Sciences, 1407(1), pp. 50–62. doi: 10.1111/nyas.13382.   edoc
Hussaarts, L., Mühlebach, S., Shah, V. P., McNeil, S., Borchard, G., Flühmann, B., Weinstein, V., Neervannan, S., Griffiths, E., Jiang, W., Wolff-Holz, E., Crommelin, D. J. A. and de Vlieger, J. S. B. (2017) “Equivalence of complex drug products: advances in and challenges for current regulatory frameworks”, Annals of the New York Academy of Sciences, 1407(1), pp. 39–49. doi: 10.1111/nyas.13347.   edoc
Aeberhard, C., Steuer, C., Saxer, C., Huber, A., Stanga, Z. and Mühlebach, S. (2017) “Physicochemical stability and compatibility testing of levetiracetam in all-in-one parenteral nutrition admixtures in daily practice”, European journal of pharmaceutical sciences, 96, pp. 449–455. doi: 10.1016/j.ejps.2016.10.015.   edoc
Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Fearon, K., Hütterer, E., Isenring, E., Kaasa, S., Krznaric, Z., Laird, B., Larsson, M., Laviano, A., Mühlebach, S., Muscaritoli, M., Oldervoll, L., Ravasco, P., Solheim, T., Strasser, F., de van der Schueren, M. and Preiser, J.-C. (2017) “ESPEN guidelines on nutrition in cancer patients”, Clinical nutrition, 36(1), pp. 11–48. doi: 10.1016/j.clnu.2016.07.015.   edoc
Engeli, R. T., Tsachaki, M., Hassan, H. A., Sager, C. P., Essawi, M. L., Gad, Y. Z., Kamel, A. K., Mazen, I. and Odermatt, A. (2017) “Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients”, The journal of sexual medicine, 14(9), pp. 1165–1174. doi: 10.1016/j.jsxm.2017.07.006.   edoc
Knöpfel, T., Pastor-Arroyo, E. M., Schnitzbauer, U., Kratschmar, D. V., Odermatt, A., Pellegrini, G., Hernando, N. and Wagner, C. A. (2017) “The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction”, Scientific reports, 7(1), p. 11018. doi: 10.1038/s41598-017-10390-2.   edoc
Dolder, P. C., Strajhar, P., Vizeli, P., Hammann, F., Odermatt, A. and Liechti, M. E. (2017) “Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects”, Frontiers in pharmacology, 8, p. 617. doi: 10.3389/fphar.2017.00617.   edoc
van Beek, A. E., Pouw, R. B., Brouwer, M. C., van Mierlo, G., Geissler, J., Ooijevaar-de Heer, P., de Boer, M., van Leeuwen, K., Rispens, T., Wouters, D. and Kuijpers, T. W. (2017) “Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma”, Frontiers in Immunology. Frontiers Media, 8, p. 1328. doi: 10.3389/fimmu.2017.01328.   edoc
Engeli, R. T., Rohrer, S. R., Vuorinen, A., Herdlinger, S., Kaserer, T., Leugger, S., Schuster, D. and Odermatt, A. (2017) “Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases”, International Journal of Molecular Sciences, 18(9), pp. 1–13. doi: 10.3390/ijms18092007.   edoc | Open Access
Aghagolzadeh, P., Radpour, R., Bachtler, M., van Goor, H., Smith, E. R., Lister, A., Odermatt, A., Feelisch, M. and Pasch, A. (2017) “Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation”, Atherosclerosis, 265, pp. 78–86. doi: 10.1016/j.atherosclerosis.2017.08.012.   edoc
Morgan, R. A., Beck, K. R., Nixon, M., Homer, N. Z. M., Crawford, A. A., Melchers, D., Houtman, R., Meijer, O. C., Stomby, A., Anderson, A. J., Upreti, R., Stimson, R. H., Olsson, T., Michoel, T., Cohain, A., Ruusalepp, A., Schadt, E. E., Björkegren, J. L. M., Andrew, R., Kenyon, C. J., Hadoke, P. W. F., Odermatt, A., Keen, J. A. and Walker, B. R. (2017) “Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity”, Scientific Reports, 7(1), p. 10633. doi: 10.1038/s41598-017-10410-1.   edoc | Open Access
Alesutan, I., Voelkl, J., Feger, M., Kratschmar, D. V., Castor, T., Mia, S., Sacherer, M., Viereck, R., Borst, O., Leibrock, C., Gawaz, M., Kuro-O, M., Pilz, S., Tomaschitz, A., Odermatt, A., Pieske, B., Wagner, C. A. and Lang, F. (2017) “Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells”, Scientific Reports, 7(1), p. 2059. doi: 10.1038/s41598-017-01882-2.   edoc | Open Access
Monzel, J. V., Budde, T., Meyer zu Schwabedissen, H. E., Schwebe, M., Bien-Möller, S., Lütjohann, D., Kroemer, H. K., Jedlitschky, G. and Grube, M. (2017) “Doxorubicin enhance oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters”, Biochemical pharmacology, 144, pp. 108–119. doi: 10.1016/j.bcp.2017.08.008.   edoc
Flesch, D., Cheung, S.-Y., Schmidt, J., Gabler, M., Heitel, P., Kramer, J., Kaiser, A., Hartmann, M., Lindner, M., Lüddens-Dämgen, K., Heering, J., Lamers, C., Lüddens, H., Wurglics, M., Proschak, E., Schubert-Zsilavecz, M. and Merk, D. (2017) “Nonacidic Farnesoid X Receptor Modulators”, Journal of Medicinal Chemistry, 60(16), pp. 7199–7205. doi: 10.1021/acs.jmedchem.7b00903.   edoc
Cramer, J. and Klebe, G. (2017) “An Allyl Protection and Improved Purification Strategy Enables the Synthesis of Functionalized Phosphonamidate Peptides”, Synthesis. GEORG THIEME VERLAG KG, 49(8), pp. 1857–1866. doi: 10.1055/s-0036-1588393.   edoc
Cramer, J., Krimmer, S. G., Fridh, V., Wulsdorf, T., Karlsson, R., Heine, A. and Klebe, G. (2017) “Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin”, ACS Chemical Biology, 12(1), pp. 225–233. doi: 10.1021/acschembio.6b00979.   edoc
Cramer, J., Schiebel, J., Wulsdorf, T., Grohe, K., Najbauer, E. E., Ehrmann, F. R., Radeva, N., Zitzer, N., Linne, U., Linser, R., Heine, A. and Klebe, G. (2017) “A False-Positive Screening Hit in Fragment-Based Lead Discovery: Watch out for the Red Herring”, Angewandte Chemie (International Edition), 56(7), pp. 1908–1913. doi: 10.1002/anie.201609824.   edoc
Cramer, J., Krimmer, S. G., Heine, A. and Klebe, G. (2017) “Paying the Price of Desolvation in Solvent-Exposed Protein Pockets: Impact of Distal Solubilizing Groups on Affinity and Binding Thermodynamics in a Series of Thermolysin Inhibitors”, Journal of Medicinal Chemistry, 60(13), pp. 5791–5799. doi: 10.1021/acs.jmedchem.7b00490.   edoc

2016

Moradi-Afrapoli, F., Oufir, M., Walter, F. R., Deli, M. A., Smieško, M., Zabela, V., Butterweck, V. and Hamburger, M. (2016) “Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro BBB and intestinal drug permeability studies”, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 264–274. doi: 10.1016/j.jpba.2016.05.039.   edoc
Jähne, E. A., Sampath, C., Butterweck, V., Hamburger, M. and Oufir, M. (2016) “Development and full validation of an UPLC-MS/MS method for the quantification of indirubin in rat plasma”, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 247–252. doi: 10.1016/j.jpba.2016.05.018.   edoc
Kettiger, H., Québatte, G., Perrone, B. and Huwyler, J. (2016) “Interactions between silica nanoparticles and phospholipid membranes”, Biochimica et biophysica acta. Elsevier, 1858(9), pp. 2163–2170. doi: 10.1016/j.bbamem.2016.06.023.   edoc
Hussner, J., Sünwoldt, J., Seibert, I., Gliesche, D. G. and Meyer zu Schwabedissen, H. E. (2016) “Pimecrolimus increases the expression of interferon-inducible genes that modulate human coronary artery cells proliferation”, European Journal of Pharmacology. Elsevier, 784, pp. 137–146. doi: 10.1016/j.ejphar.2016.05.020.   edoc
Buck, J., Huwyler, J., Kühl, P. and Dischinger, A. (2016) “Pediatric Dispersible Tablets: a Modular Approach for Rapid Prototyping”, Pharmaceutical research. Plenum Press, 33(8), pp. 2043–2055. doi: 10.1007/s11095-016-1946-9.   edoc
Preisig, D., Roth, R., Tognola, S., Varum, F. J. O., Bravo, R., Cetinkaya, Y., Huwyler, J. and Puchkov, M. (2016) “Mucoadhesive microparticles for local treatment of gastrointestinal diseases”, European journal of pharmaceutics and biopharmaceutics. Elsevier, 105, pp. 156–165. doi: 10.1016/j.ejpb.2016.06.009.   edoc
Gliesche, D. G., Hussner, J., Witzigmann, D., Porta, F., Glatter, T., Schmidt, A., Huwyler, J. and Meyer Zu Schwabedissen, H. E. (2016) “Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries”, Molecular Pharmaceutics. American Chemical Society, 13(7), pp. 2290–2300. doi: 10.1021/acs.molpharmaceut.6b00033.   edoc
Bischoff, T., Vogl, C. R., Ivemeyer, S., Klarer, F., Meier, B., Hamburger, M. and Walkenhorst, M. (2016) “Plant and natural product based household remedies manufactured and used by farmers of six central Swiss cantons to treat livestock”, Livestock science. Elsevier, 189, pp. 110–125. doi: 10.1016/j.livsci.2016.05.003.   edoc
Hu, Z., Wahl, J., Hamburger, M. and Vedani, A. (2016) “Molecular mechanisms of endocrine and metabolic disruption: An in silico study on antitrypanosomal natural products and some derivatives”, Toxicology Letters. Elsevier, 252, pp. 29–41. doi: 10.1016/j.toxlet.2016.04.013.   edoc
Eigenmann, D. E., Dürig, C., Jähne, E. A., Smieško, M., Culot, M., Gosselet, F., Cecchelli, R., Cederberg Helms, H. C., Brodin, B., Wimmer, L., Mihovilovic, M. D., Hamburger, M. and Oufir, M. (2016) “In vitro blood-brain barrier permeability predictions of piperine analogues with GABAA receptor modulating properties”, European Journal of Pharmaceutics and Biopharmaceutics. Elsevier, 103, pp. 118–126. doi: 10.1016/j.ejpb.2016.03.029.   edoc
Witzigmann, D., Quagliata, L., Schenk, S. H., Quintavalle, C., Terracciano, L. M. and Huwyler, J. (2016) “Variable asialoglycoprotein-receptor 1 expression in liver disease: Implications for therapeutic intervention”, Hepatology research . Blackwell, 46(7), pp. 686–696. doi: 10.1111/hepr.12599.   edoc
Eberle, V. A., Häring, A., Schoelkopf, J., Gane, P. A. C., Huwyler, J. and Puchkov, M. (2016) “In silico and in vitro methods to optimize the performance of experimental gastroretentive floating mini-tablets”, Drug development and industrial pharmacy. Informa Healthcare, 42(5), pp. 808–817. doi: 10.3109/03639045.2015.1078350.   edoc
Canonica, J., Sergi, C., Maillard, M., Klusonova, P., Odermatt, A., Koesters, R., Loffing-Cueni, D., Loffing, J., Rossier, B., Frateschi, S. and Hummler, E. (2016) “Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype”, Pflügers Archiv : European journal of physiology. Springer, 468(5), pp. 895–908. doi: 10.1007/s00424-015-1785-2.   edoc
Mani, O., Nashev, L. G., Livelo, C., Baker, M. E. and Odermatt, A. (2016) “Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone”, The Journal of steroid biochemistry and molecular biology. Elsevier, 159, pp. 31–40. doi: 10.1016/j.jsbmb.2016.02.017.   edoc
Riede, J., Poller, B., Umehara, K.- ichi, Huwyler, J. and Camenisch, G. (2016) “New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data”, European journal of pharmaceutical sciences. Elsevier, 86, pp. 96–102. doi: 10.1016/j.ejps.2016.02.022.   edoc
Odermatt, A., Strajhar, P. and Engeli, R. T. (2016) “Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools”, The Journal of steroid biochemistry and molecular biology. Elsevier, 158, pp. 9–21. doi: 10.1016/j.jsbmb.2016.01.009.   edoc
Grabe, H. J., Wittfeld, K., Van der Auwera, S., Janowitz, D., Hegenscheid, K., Habes, M., Homuth, G., Barnow, S., John, U., Nauck, M., Völzke, H., Meyer zu Schwabedissen, H. E., Freyberger, H. J. and Hosten, N. (2016) “Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample”, Human brain mapping. Wiley-Liss, 37(4), pp. 1602–1613. doi: 10.1002/hbm.23123.   edoc
Bloechliger, M., Ceschi, A., Rüegg, S., Kupferschmidt, H., Krähenbühl, S., Jick, S. S., Meier, C. R. and Bodmer, M. (2016) “Risk of Seizures Associated with Antidepressant Use in Patients with Depressive Disorder: Follow-up Study with a Nested Case-Control Analysis Using the Clinical Practice Research Datalink”, Drug Safety . Springer, 39(4), pp. 307–321. doi: 10.1007/s40264-015-0363-z.   edoc
Seliger, C., Meier, C. R., Jick, S. S., Uhl, M., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) “Use of cardiac glycosides and risk of glioma”, Journal of Neuro-Oncology . Springer Science+Business Media B.V, 127(2), pp. 321–328. doi: 10.1007/s11060-015-2036-2.   edoc
Ramming, T., Kanemura, S., Okumura, M., Inaba, K. and Appenzeller-Herzog, C. (2016) “Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover”, Redox biology. Elsevier, 7, pp. 14–20. doi: 10.1016/j.redox.2015.11.004.   edoc
Strajhar, P., Schmid, Y., Liakoni, E., Dolder, P. C., Rentsch, K. M., Kratschmar, D. V., Odermatt, A. and Liechti, M. E. (2016) “Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects”, Journal of Neuroendocrinology. Wiley, 28(3), p. 12374. doi: 10.1111/jne.12374.   edoc | Open Access
Coqueiro, A., Choi, Y. H., Verpoorte, R., Sankar Gupta, K. B. S., De Mieri, M., Hamburger, M., Marx Young, M. C., Stapleton, P., Gibbons, S. and da Silva Bolzani, V. (2016) “Anti-staphylococcal prenylated acylphoroglucinol and xanthones from Kielmeyera variabilis (Clusiaceae)”, Journal of natural products. American Society of Pharmacognosy, 79(3), pp. 470–476. doi: 10.1021/acs.jnatprod.5b00858.   edoc
Eigenmann, D. E., Jähne, E. A., Smiesko, M., Hamburger, M. and Oufir, M. (2016) “Validation of an immortalized human (hBMEC) in vitro blood-brain barrier model”, Analytical and Bioanalytical Chemistry. Springer, 408(8), pp. 2095–2107. doi: 10.1007/s00216-016-9313-6.   edoc
Seliger, C., Ricci, C., Meier, C. R., Bodmer, M., Jick, S. S., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) “Diabetes, use of antidiabetic drugs, and the risk of glioma”, Neuro-Oncology. Oxford University Press, 18(3), pp. 340–349. doi: 10.1093/neuonc/nov100.   edoc | Open Access
Bornand, D., Toovey, S., Jick, S. S. and Meier, C. R. (2016) “The risk of new onset depression in association with influenza - a population-based observational study”, Brain, Behavior and Immunity . Elsevier, 53, pp. 131–137. doi: 10.1016/j.bbi.2015.12.005.   edoc
Requena, G., Huerta, C., Gardarsdottir, H., Logie, J., González-González, R., Abbing-Karahagopian, V., Miret, M., Schneider, C., Souverein, P. C., Webb, D., Afonso, A., Boudiaf, N., Martin, E., Oliva, B., Alvarez, A., De Groot, M. C. H., Bate, A., Johansson, S., Schlienger, R., Reynolds, R., Klungel, O. H. and de Abajo, F. J. (2016) “Hip/femur fractures associated with the use of benzodiazepines (anxiolytics, hypnotics and related drugs): a methodological approach to assess consistencies across databases from the PROTECT-EU project”, Pharmacoepidemiology and drug safety. Wiley, 25(1), pp. 66–78. doi: 10.1002/pds.3816.   edoc
Huerta, C., Abbing-Karahagopian, V., Requena, G., Oliva, B., Alvarez, Y., Gardarsdottir, H., Miret, M., Schneider, C., Gil, M., Souverein, P. C., De Bruin, M. L., Slattery, J., De Groot, M. C. H., Hesse, U., Rottenkolber, M., Schmiedl, S., Montero, D., Bate, A., Ruigomez, A., García-Rodríguez, L. A., Johansson, S., de Vries, F., Schlienger, R. G., Reynolds, R. F., Klungel, O. H. and de Abajo, F. J. (2016) “Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project”, Pharmacoepidemiology and drug safety. John Wiley, 25(1), pp. 56–65. doi: 10.1002/pds.3825.   edoc
Spoendlin, J., Karatas, G., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) “Rosacea in Patients with Ulcerative Colitis and Crohn’s Disease: a Population-based Case-control Study”, Inflammatory Bowel Diseases. Lippincott Williams & Wilkins, 22(3), pp. 680–687. doi: 10.1097/MIB.0000000000000644.   edoc
Corradi, E., De Mieri, M., Cadisch, L., Abbet, C. ., Hamburger, M. and Potterat, O. (2016) “New Acylated Flavonol Glycosides and a Phenolic Profile of Pritzelago alpina, a Forgotten Edible Alpine Plant ”, Chemistry & Biodiversity. Helvetica Chimica Acta, 13(2), pp. 188–197. doi: 10.1002/cbdv.201500353.   edoc
Ríos Quiroz, A., Lamerz, J., De Cunha, T., Boillon, A., Adler, M., Finkler, C., Huwyler, J., Schmidt, R., Mahler, H.-C. and Koulov, A. V. (2016) “Factors Governing the Precision of Subvisible Particle Measurement Methods - A Case Study with a Low-Concentration Therapeutic Protein Product in a Prefilled Syringe”, Pharmaceutical research. Springer, 33(2), pp. 450–461. doi: 10.1007/s11095-015-1801-4.   edoc
Wilson, J. C., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) “Inflammatory Bowel Disease and the Risk of Autoimmune Diseases”, Journal of Crohn’s and Colitis. Elsevier, 10(2), pp. 186–193. doi: 10.1093/ecco-jcc/jjv193.   edoc
Mathaes, R., Mahler, H.-C., Buettiker, J.-P., Roehl, H., Lam, P., Brown, H., Luemkemann, J., Adler, M., Huwyler, J., Streubel, A. and Mohl, S. (2016) “The pharmaceutical vial capping process; Container closure systems, capping equipment, regulatory framework, and seal quality tests”, European journal of pharmaceutics and biopharmaceutics. Elsevier, 99, pp. 54–64. doi: 10.1016/j.ejpb.2015.11.016.   edoc
Rizner, T. L., Sasano, H., Choi, M. H., Odermatt, A. and Adamski, J. (2016) “Recommendations for description and validation for antibodies for research use”, The journal of steroid biochemistry and molecular biology. Pergamon, 156, pp. 40–42. doi: 10.1016/j.jsbmb.2015.11.021.   edoc
Rysz, M., Bromek, E., Haduch, A., Liskova, B., Wójcikowski, J. and Daniel, W. A. (2016) “The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11”, Biochemical Pharmacology. Elsevier, 112, pp. 82–89. doi: 10.1016/j.bcp.2016.04.017.   edoc
Rysz, M., Bromek, E. and Daniel, W. A. (2016) “Activation of brain serotonergic system by repeated intracerebral administration of 5-hydroxytryptophan (5-HTP) decreases the expression and activity of liver cytochrome P450”, Biochemical Pharmacology. Elsevier, 99, pp. 113–122. doi: 10.1016/j.bcp.2015.11.014.   edoc
Kindo, M., Gerelli, S., Bouitbir, J., Hoang Minh, T., Charles, A.-L., Mazzucotelli, J.-P., Zoll, J., Piquard, F. and Geny, B. (2016) “Left Ventricular Transmural Gradient in Mitochondrial Respiration Is Associated with Increased Sub-Endocardium Nitric Oxide and Reactive Oxygen Species Productions”, Frontiers in Physiology. Frontiers Media, 7, p. 331. doi: 10.3389/fphys.2016.00331.   edoc
Mancuso, R. V., Welzenbach, K., Steinberger, P., Krähenbühl, S. and Weitz-Schmidt, G. (2016) “Downstream effect profiles discern different mechanisms of integrin αLβ2 inhibition”, Biochemical Pharmacology. Elsevier, 119, pp. 42–55. doi: 10.1016/j.bcp.2016.09.002.   edoc
Mühlebach , S. F. (2016) “Arzneimittel bei HomeCare-Ernährung: Gibt es pharmazeutisches Optimierungspotenzial? (Drug and nutrition in the home care setting: is there potential for pharmaceutical improvement ”, Aktuel Ernahrungsmed. Georg Thieme, 41(3), pp. 190–195. doi: 10.1055/s-0042-105715.   edoc
de Vlieger , J. S. B., Borchard, G., Shah, V. P., Flühmann, B., Neervannan, S. and Mühlebach , S. F. (2016) “Is the EU ready for non-biological complex drug products?”, Generics and biosimilars initiative journal, 5(3), pp. 101–102. doi: 10.5639/gabij.2016.0503.026.   edoc
Bouitbir, J., Singh, F., Charles, A.-L., Schlagowski, A.-I., Bonifacio, A., Echaniz-Laguna, A., Geny, B., Krahenbuhl, S. and Zoll, J. (2016) “Statins Trigger Mitochondrial Reactive Oxygen Species-Induced Apoptosis in Glycolytic Skeletal Muscle”, Antioxidants and Redox Signaling. Mary Ann Liebert, 24(2), pp. 84–98. doi: 10.1089/ars.2014.6190.   edoc

2015

Kettiger, H., Karaman, D. S., Schiesser, L., Rosenholm, J. M. and Huwyler, J. (2015) “Comparative safety evaluation of silica-based particles”, Toxicology in vitro. Elsevier, 30(1), pp. 355–363. doi: 10.1016/j.tiv.2015.09.030.   edoc
Moghadam, S. E., Ebrahimi, S. N., Gafner, F., Ochola, J. B., Marubu, R. M., Lwande, W., Frei Haller, B., Salehi, P. and Hamburger, M. (2015) “Metabolite profiling for caffeic acid oligomers in Satureja biflora”, Industrial Crops and Products. Elsevier, 76, pp. 892–899. doi: 10.1016/j.indcrop.2015.07.059.   edoc
Arnet, I., Altermatt, M., Roggo, Y. and Schnetzler, G. (2015) “Pharmaceutical quality of eight generics of ceftriaxone preparation for injection in Eastern Asia”, Journal of chemotherapy . Taylor & Francis Group, 27(6), pp. 337–342. doi: 10.1179/1973947814Y.0000000208.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) “Association of hormone therapy and incident gout: population-based case-control study”, Menopause. Lippincott, 22(12), pp. 1335–1342. doi: 10.1097/GME.0000000000000474.   edoc
Favre-Godal, Q., Dorsaz, S., Queiroz, E. F., Marcourt, L., Ebrahimi, S. N., Allard, P.-M., Voinesco, F., Hamburger, M., Gupta, M. P., Gindro, K., Sanglard, D. and Wolfender, J.-L. (2015) “Identification of novel anti-Candida cassane type diterpenes from the roots bark of Swartzia simplex (Sw.) Spreng”, Journal of Natural Products. American Chemical Society, 78(12), pp. 2994–3004. doi: 10.1021/acs.jnatprod.5b00744.   edoc
Arnet, I., Seidling, H. M. and Hersberger, K. E. (2015) “Unerwünschte Arzneimittelwirkungen in der Offizinapotheke”, Therapeutische Umschau. Hans Huber, 72(11/12), pp. 687–692. doi: 10.1024/0040-5930/a000738.   edoc
Folzer, E., Khan, T., Schmidt, R., Finkler, C., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) “Determination of the Density of Protein Particles Using a Suspended Microchannel Resonator”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(12), pp. 4034–4040. doi: 10.1002/jps.24635.   edoc
Boll, B., Folzer, E., Finkler, C., Huwyler, J., Mahler, H.-C., Schmidt, R. and Koulov, A. V. (2015) “Comparative Evaluation of Two Methods for Preparative Fractionation of Proteinaceous Subvisible Particles-Differential Centrifugation and FACS”, Pharmaceutical research. Springer, 32(12), pp. 3952–3964. doi: 10.1007/s11095-015-1755-6.   edoc
Kaserer, T., Beck, K., Akram, M., Odermatt, A. and Schuster, D. (2015) “Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases”, Molecules. MDPI, 20(12), pp. 22799–22832. doi: 10.3390/molecules201219880.   edoc
Shelton, L. M., Lister, A., Walsh, J., Jenkins, R. E., Wong, M. H. L., Rowe, C., Ricci, E., Ressel, L., Fang, Y., Demougin, P., Vukojevic, V., O’Neill, P. M., Goldring, C. E., Kitteringham, N. R., Park, B. K., Odermatt, A. and Copple, I. M. (2015) “Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney”, Kidney international. Springer, 88(6), pp. 1261–1273. doi: 10.1038/ki.2015.286.   edoc
Becker, C., Wilson, J. C., Jick, S. S. and Meier, C. R. (2015) “Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: a case-control analysis”, International journal of cancer. Alan R. Liss, 137(10), pp. 2424–2431. doi: 10.1002/ijc.29601.   edoc
Seibert, J. K., Quagliata, L., Quintavalle, C., Hammond, T. G., Terracciano, L. and Odermatt, A. (2015) “A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer”, Cancer medicine. Wiley, 4(11), pp. 1717–1729. doi: 10.1002/cam4.517.   edoc
Di Chiara, M., Glaudemans, B., Loffing-Cueni, D., Odermatt, A., Al-Hasani, H., Devuyst, O., Faresse, N. and Loffing, J. (2015) “Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney”, American journal of physiology. Gastrointestinal and liver physiology. American Physiological Society, 309(9), pp. F779-F790. doi: 10.1152/ajprenal.00139.2015.   edoc
Becker, C., Jick, S. S., Meier, C. R. and Bodmer, M. (2015) “No evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: a case-control study”, BMC cancer. BioMed Central, 15, p. 719. doi: 10.1186/s12885-015-1719-6.   edoc
Haegler, P., Grünig, D., Berger, B., Krähenbühl, S. and Bouitbir, J. (2015) “Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: a cell model for idiosyncratic toxicity”, Toxicology. Elsevier, 336, pp. 48–58. doi: 10.1016/j.tox.2015.07.015.   edoc
Imfeld, P., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) “Benzodiazepine Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case-Control Analysis”, Drug safety. Adis International, 38(10), pp. 909–919. doi: 10.1007/s40264-015-0319-3.   edoc
Glanzmann, C., Frey, B., Meier, C. R. and Vonbach, P. (2015) “Analysis of medication prescribing errors in critically ill children”, European journal of pediatrics. Springer, 174(10), pp. 1347–1355. doi: 10.1007/s00431-015-2542-4.   edoc
Allmendinger, A., Mueller, R., Huwyler, J., Mahler, H.-C. and Fischer, S. (2015) “Sterile Filtration of Highly Concentrated Protein Formulations: Impact of Protein Concentration, Formulation Composition, and Filter Material”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(10), pp. 3319–3329. doi: 10.1002/jps.24561.   edoc
Farimani, M. M., Bahadori, M. B., Koulaei, S. A., Salehi, P., Ebrahimi, S. N., Khavasi, H. R. and Hamburger, M. (2015) “New ursane triterpenoids from Salvia urmiensis Bunge: absolute configuration and anti-proliferative activity”, Fitoterapia. Elsevier, 106, pp. 1–6. doi: 10.1016/j.fitote.2015.07.017.   edoc
Du, K., De Mieri, M., Neuburger, M., Zietsman, P. C., Marston, A., van Vuuren, S. F., Ferreira, D., Hamburger, M. and van der Westhuizen, J. H. (2015) “Labdane and clerodane diterpenes from Colophospermum mopane”, Journal of Natural Products. American Chemical Society, 78(10), pp. 2494–2504. doi: 10.1021/acs.jnatprod.5b00729.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) “Poorly controlled type 2 diabetes mellitus is associated with a decreased risk of incident gout: a population-based case-control study”, Annals of the rheumatic diseases. British Medical Association, 74(9), pp. 1651–1658. doi: 10.1136/annrheumdis-2014-205337.   edoc
Werk, T., Huwyler, J., Hafner, M., Luemkemann, J. and Mahler, H.-C. (2015) “An Impedance-Based Method to Determine Reconstitution Time for Freeze-Dried Pharmaceuticals”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2948–2955. doi: 10.1002/jps.24443.   edoc
Folzer, E., Diepold, K., Bomans, K., Finkler, C., Schmidt, R., Bulau, P., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) “Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2824–2831. doi: 10.1002/jps.24509.   edoc
Kunze, A., Poller, B., Huwyler, J. and Camenisch, G. (2015) “Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins”, Drug Metabolism and Personalized Therapy. de Gruyter, 30(3), pp. 175–188. doi: 10.1515/dmdi-2015-0003.   edoc
Hussner, J., Begung, R., Boettcher, K., Gliesche, D. G., Prestin, K. and Meyer zu Schwabedissen, H. E. (2015) “Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery”, Vascular Pharmacology . Elsevier, 72, pp. 25–34. doi: 10.1016/j.vph.2015.06.006.   edoc
Moridi Farimani, M., Abbas-Mohammadi, M., Esmaeili, M.-A., Salehi, P., Nejad-Ebrahimi, S., Sonboli, A. and Hamburger, M. (2015) “Seco-ursane type triterpenoids from Salvia urmiensis with apoptosis-inducing activity”, Planta medica. Thieme, 81(14), pp. 1290–1295. doi: 10.1055/s-0035-1546256.   edoc
Wilson, J. C., Toovey, S., Jick, S. S. and Meier, C. R. (2015) “Previously diagnosed influenza infections and the risk of developing epilepsy”, Epidemiology and infection. Cambridge University Press, 143(11), pp. 2408–2415. doi: 10.1017/S0950268814003380.   edoc
Bonifacio, A., Sanvee, G. M., Bouitbir, J. and Krähenbühl, S. (2015) “The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity”, Biochimica et biophysica acta. Molecular cell research. Elsevier, 1853(8), pp. 1841–1849. doi: 10.1016/j.bbamcr.2015.04.010.   edoc
Roberts, P. A., Bouitbir, J., Bonifacio, A., Singh, F., Kaufmann, P., Urwyler, A. and Krähenbühl, S. (2015) “Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency”, American Journal of Physiology. Endocrinology and Metabolism. American Physiological Society, 309(3), pp. E265-E274. doi: 10.1152/ajpendo.00001.2015.   edoc
Liakoni, E., Rätz Bravo, A. E. and Krähenbühl, S. (2015) “Hepatotoxicity of New Oral Anticoagulants (NOACs)”, Drug safety. Adis International, 38(8), pp. 711–720. doi: 10.1007/s40264-015-0317-5.   edoc
Oufir, M., Seiler, C., Gerodetti, M., Gerber, J., Fürer, K., Mennet-von Eiff, M., Elsas, S.-M., Brenneisen, R., von Mandach, U., Hamburger, M. and Potterat, O. (2015) “Quantification of burfadienolides in bryophyllum pinnatum leaves and manufactured products by UHPLC-ESIMS/MS”, Planta Medica. Georg Thieme Verlag, 81(12/13), pp. 1190–1197. doi: 10.1055/s-0035-1546126.   edoc
Du, K., De Mieri, M., Saxena, P., Phungula, K. V., Zietsman, P. C., Hering, S., van der Westhuizen, J. H. and Hamburger, M. (2015) “HPLC-​Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana”, Planta Medica. Georg Thieme Verlag, 81(12/13), pp. 1154–1162. doi: 10.1055/s-0035-1545929.   edoc
Allmendinger, A., Mueller, R., Schwarb, E., Chipperfield, M., Huwyler, J., Mahler, H.-C. and Fischer, S. (2015) “Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection”, Pharmaceutical research. Plenum Press, 32(7), pp. 2229–2240. doi: 10.1007/s11095-014-1611-0.   edoc
Bloechliger, M., Rüegg, S., Jick, S. S., Meier, C. R. and Bodmer, M. (2015) “Antipsychotic drug use and the risk of seizures: follow-up study with a nested case-control analysis”, CNS drugs. Springer, 29(7), pp. 591–603. doi: 10.1007/s40263-015-0262-y.   edoc
Layton, J. B., Meier, C. R., Sharpless, J. L., Stürmer, T., Jick, S. S. and Brookhart, M. A. (2015) “Comparative Safety of Testosterone Dosage Forms”, JAMA internal medicine. American Medical Association, 175(7), pp. 1187–1196. doi: 10.1001/jamainternmed.2015.1573.   edoc
Ślusarczyk, S., Topolski, J., Domaradzki, K., Adams, M., Hamburger, M. and Matkowski, M. (2015) “Isolation and fast selective determinatino of nor-abhietanoid diterpenoids from Perovskia atriplicifolia roots using LC-ESIMS/MS with multiple reaction monitoring”, Natural Product Communications . Natural Product Incorporation , 10(7), pp. 1149–1152.   edoc
Odermatt, A. and Klusonova, P. (2015) “11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story”, The journal of steroid biochemistry and molecular biology. Pergamon, 151, pp. 85–92. doi: 10.1016/j.jsbmb.2014.08.011.   edoc
Tsachaki, M., Birk, J., Egert, A. and Odermatt, A. (2015) “Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions”, Biochimica et biophysica acta. Molecular cell research. Elsevier, 1853(7), pp. 1672–1682. doi: 10.1016/j.bbamcr.2015.04.002.   edoc
Reinau, D., Surber, C., Jick, S. S. and Meier, C. R. (2015) “Nonsteroidal anti-inflammatory drugs and the risk of nonmelanoma skin cancer”, International Journal of Cancer. Wiley, 137(1), pp. 144–153. doi: 10.1002/ijc.29357.   edoc
Preisig, D., Weingartner, M., Varum, F. J. O., Bravo, R., Alles, R., Huwyler, J. and Puchkov, M. (2015) “Marker-ion analysis for quantification of mucoadhesivity of microparticles in particle-retention assays”, International journal of pharmaceutics. Elsevier, 487(1-2), pp. 157–166. doi: 10.1016/j.ijpharm.2015.04.020.   edoc