Bachmann, F., Duthaler, U., Meyer Zu Schwabedissen, H. E., Puchkov, M., Huwyler, J., Haschke, M. and Krähenbühl, S. (2021) “Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2”, Clinical Pharmacology and Therapeutics. Wiley, 109(6), pp. 1505–1516. doi: 10.1002/cpt.2141.   edoc
Walters, N. A., de Beer, D., de Villiers, A., Danton, O., Hamburger, M. and Joubert, E. (2021) “Comprehensive off-line CCC x LC-DAD-MS separation of Cyclopia pubescens Eckl. & Zeyh. phenolic compounds and structural elucidation of isolated compounds”, Phytochemical Analysis. Wiley, 32(3), pp. 347–361. doi: 10.1002/pca.2981.   edoc
Jere, D., Sediq, A. S., Huwyler, J., Vollrath, I., Kardorff, M. and Mahler, H.-C. (2021) “Challenges for cell-based medicinal products from a pharmaceutical product perspective”, Journal of Pharmaceutical Sciences. Elsevier, 110(5), pp. 1900–1908. doi: 10.1016/j.xphs.2020.11.040.   edoc
Duthaler, U., Weber, M., Hofer, L., Chaccour, C., Maia, M., Müller, P., Krähenbühl, S. and Hammann, F. (2021) “The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes”, PLoS Pathogens. Public Library of Science, 17(3), p. e1009382. doi: 10.1371/journal.ppat.1009382.   edoc | Open Access
Wagner-Hattler, L., Kiene, K., Bielicki, J., Pfister, M., Puchkov, M. and Huwyler, J. (2021) “High Acceptability of an Orally Dispersible Tablet Formulation by Children”, Children. MDPI, 8(3), p. 194. doi: 10.3390/children8030194.   edoc
Spoendlin, J., Blozik, E., Graber, S. M., Rauch, M., Marxer, C. A., Rüegg, S., Meier, C., Winterfeld, U. and Panchaud, A. (2021) “Use of valproate in pregnancy and in women of childbearing age between 2014 and 2018 in Switzerland: a retrospective analysis of Swiss healthcare claims data”, Swiss medical weekly. EMH Schweizerischer Ärzteverlag, 151, p. w20386. doi: 10.4414/smw.2021.20386.   edoc
Einfalt, T., Detampel, P., Häussinger, D., Casper, J., Meier, C., Puchkov, M. and Huwyler, J. (2021) “Hydroxychloroquine immediate release tablets: Formulation and evaluation of a solid dosage form”, ChemRxiv Preprint. doi: 10.26434/chemrxiv.14170508.v1.   edoc | Open Access
Schnoz, C., Moser, S., Kratschmar, D. V., Odermatt, A., Loffing-Cueni, D. and Loffing, J. (2021) “Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC”, Pflügers Archiv : European journal of physiology. Springer, 473(1), pp. 79–93. doi: 10.1007/s00424-020-02491-1.   edoc | Open Access
Beck, K. R. and Odermatt, A. (2021) “Antifungal therapy with azoles and the syndrome of acquired mineralocorticoid excess”, Molecular and Cellular Endocrinology. Elsevier, 524, p. 111168. doi: 10.1016/j.mce.2021.111168.   edoc | Open Access
Marxer, C. A., Frey, N., Bodmer, M., Bircher, A., Jick, S. S., Meier, C. R. and Spoendlin, J. (2021) “Survival after Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis: A UK-based Cohort Study”, Journal of Investigative Dermatology. Elsevier, 141(5), pp. 1349–1351.e1. doi: 10.1016/j.jid.2020.09.034.   edoc
Inderbinen, S. G., Zogg, M., Kley, M., Smieško, M. and Odermatt, A. (2021) “Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole”, Toxicology and applied pharmacology. Academic Press, 412, p. 115387. doi: 10.1016/j.taap.2020.115387.   edoc | Open Access
Leuppi-Taegtmeyer, A. B., Reinau, D., Yilmaz, S., Rüegg, S., Krähenbühl, S., Jick, S. S., Leuppi, J. D. and Meier, C. R. (2021) “Antiseizure drugs and risk of developing smoking-related chronic obstructive pulmonary disease or lung cancer: A population-based case-control study”, British Journal of Clinical Pharmacology. Wiley, 87(3), pp. 1253–1263. doi: 10.1111/bcp.14501.   edoc
Schröter, A., Koulov, A. V., Huwyler, J., Mahler, H.-C. and Jahn, M. (2021) “4-Hydroxynonenal is An Oxidative Degradation Product of Polysorbate 80”, Journal of Pharmaceutical Sciences, 110, pp. 2524–2530. doi: 10.1016/j.xphs.2021.01.027.
Human, C., Danton, O., De Beer, D., Maruyama, T., Alexander, L., Malherbe, C., Hamburger, M. and Joubert, E. (2021) “Identification of a novel di-C-glycosyl dihydrochalcone and the thermal stability of polyphenols in model ready-to-drink beverage solutions with Cyclopia subternata extract as functional ingredient”, Food Chemistry, 351, p. 129273. doi: 10.1016/j.foodchem.2021.129273.
Schreiner, V., Detampel, P., Jirkof, P., Puchkov, M. and Huwyler, J. (2021) “Buprenorphine loaded PLGA microparticles: Characterization of a sustained-release formulation”, Journal of Drug Delivery Science and Technology, 63, p. 102558. doi: 10.1016/j.jddst.2021.102558.
Chander, N., Morstein, J., Bolten, J. S., Shemet, A., Cullis, P. R., Trauner, D. and Witzigmann, D. (2021) “Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release”, Small (Weinheim an der Bergstrasse, Germany), 17, p. 2008198. doi: 10.1002/smll.202008198.
Pinto, M. E. F., Chan, L. Y., Koehbach, J., Devi, S., Gründemann, C., Gruber, C. W., Gomes, M., Bolzani, V. S., Cilli, E. M. and Craik, D. J. (2021) “Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes”, Journal of natural products, p. Pub ahead of print. doi: 10.1021/acs.jnatprod.0c01069.
Wang, J. T., Danton, O., Treyer, A. and Hamburger, M. (2021) “Development of a solid-supported cysteinyl probe for the isolation of electrophiles from plant pollen extracts”, Talanta, 228, p. 122216. doi: 10.1016/j.talanta.2021.122216.
Schittny, A., Waldner, S., Duthaler, U., Vorobyev, A., Abramovich, R., Krähenbühl, S., Puchkov, M. and Huwyler, J. (2021) “Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans”, pharmaceutics, 13(401), pp. 1–17. doi: 10.3390/pharmaceutics13030401.
Schuster, J., Probst, C. E., Mahler, H.-C., Joerg, S., Huwyler, J. and Mathaes, R. (2021) “Assessing Particle Formation of Biotherapeutics in Biological Fluids”, Journal of Pharmaceutical Sciences, 110(4), pp. 1527–1532. doi: 10.1016/j.xphs.2020.12.038.
Dopler, A., Stibitzky, S., Hevey, R., Mannes, M., Guariento, M., Höchsmann, B., Schrezenmeier, H., Ricklin, D. and Schmidt, C. Q. (2021) “Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces”, Frontiers in immunology, 12, p. 615748. doi: 10.3389/fimmu.2021.615748.
Schuster, J., Mahler, H.-C., Joerg, S., Kamuju, V., Huwyler, J. and Mathaes, R. (2021) “Stability of Monoclonal Antibodies after Simulated Subcutaneous Administration”, Journal of pharmaceutical sciences, 110, pp. 2386–2394. doi: 10.1016/j.xphs.2021.03.007.
Keller, M., Fankhauser, S., Giezendanner, N., König, M., Keresztes, F., Danton, O., Fertig, O., Marcourt, L., Hamburger, M., Butterweck, V. and Potterat, O. (2021) “Saponins from Saffron Corms Inhibit the Gene Expression and Secretion of Pro-Inflammatory Cytokines”, J. Nat. Prod, 84, pp. 630–645. doi: 10.1021/acs.jnatprod.0c01220.
Osterwalder, M., Bolten, J. S., Rodgers, G., Schulz, G., Tanner, C., Cörek, E., Huwyler, J. and Müller, B. (2021) “Three-dimensional X-ray microscopy of zebra sh larvae”, Bioinspiration, Biomimetics, and Bioreplication XI, 11586, p. 115860J. doi: 10.1117/12.2583639.
Khademian, A., Tabefam, M., Mazarei, Z., Kanani, M. R., Sepehri, H., Delphi, L., Danton, O., Hamburger, M. and Farimani (2021) “Chemical constituents and cytotoxic activity of Stachys pilifera Benth”, S. Afr. J. Bot, 139, pp. 1–4. doi: 10.1016/j.sajb.2021.02.022.
Preisig, D., Varum, F., Bravo, R., Hartig, C., Spleiss, J., Abbes, S., Caobelli, F., Wild, D., Puchkov, M., Huwyler, J. and Haschke, M. (2021) “Colonic delivery of metronidazole-loaded capsules for local treatment of bacterial infections: a clinical pharmacoscintigraphy study”, European Journal of Pharmaceutics and Biopharmaceutics, 165, pp. 22–30. doi: 10.1016/j.ejpb.2021.05.002.
Salm, A., Krishnan, S. R., Collu, M., Danton, O., Hamburger, M., Leonti, M., Almanza, G. and Gertsch, J. (2021) “Phylobioactive hotspots in plant resources used to treat Chagas disease”, iScience, 15, p. 102310. doi: 10.1016/j.isci.2021.102310.
Chabane, S., Boudjelal, A., Keller, M., Doubakh, S. and Potterat, O. (2021) “Teucrium polium - wound healing potential, toxicity and polyphenolic profile”, South African Journal of Botany, 137, pp. 228–235. doi: 10.1016/j.sajb.2020.10.017.
Santos, S., Zurfluh, L., Mennet, M., Potterat, O., von Mandach, U., Hamburger, M. and Simões-Wüst, A. P. (2021) “Bryophyllum pinnatum compounds inhibit oxytocin-induced signalling pathways in human myometrial cells”, Frontiers Pharmacol, 12, p. 632986. doi: 10.3389/fphar.2021.632986.
Fischer, A., Smie�ko, M., Sellner, M. and Lill, M. A. (2021) “Decision Making in Structure-Based Drug Discovery: Visual Inspection of Docking Results”, Journal of medicinal chemistry, 64(5), pp. 2489–2500. doi: 10.1021/acs.jmedchem.0c02227.
Fischer, A., Sellner, M., Mitusińska, K., Bzówka, M., Lill, M. A., Góra, A. and Smie�ko, M. (2021) “Computational Selectivity Assessment of Protease Inhibitors against SARS-CoV-2”, International journal of molecular sciences, 22(4), p. 2065. doi: 10.3390/ijms22042065.
Fischer, A., Häuptli, F., Lill, M. A. and Smie�ko, M. (2021) “Computational Assessment of Combination Therapy of Androgen Receptor-Targeting Compounds”, Journal of chemical information and modeling, 61(2), pp. 1001–1009. doi: 10.1021/acs.jcim.0c01194.
Fischer, A., Frehner, G., Lill, M. A. and Smie�ko, M. (2021) “Conformational Changes of Thyroid Receptors in Response to Antagonists”, Journal of chemical information and modeling, 61(2), pp. 1010–1019. doi: 10.1021/acs.jcim.0c01403.
Nicolle, L., Casper, J., Willimann, M., Journot, C. M. A., Detampel, P., Einfalt, T., Grisch-Chan, H. M., Thöny, B., Gerber-Lemaire, S. and Huwyler, J. (2021) “Development of Covalent Chitosan-Polyethylenimine Derivatives as Gene Delivery Vehicle: Synthesis, Characterization, and Evaluation”, International Journal of Molecular Sciences, 22(8), p. 3828. doi: 10.3390/ijms22083828.
Witzigmann, D., Grossen, P., Quintavalle, C., Lanzafame, M., Schenk, S. H., Tran, X.-T., Englinger, B., Hauswirth, P., Grünig, D., van Schoonhoven, S., Krähenbühl, S., Terracciano, L. M., Berger, W., Piscuoglio, S., Quagliata, L., Rommelaere, J., Nüesch, J. P. F. and Huwyler, J. (2021) “Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma”, Journal of controlled release : official journal of the Controlled Release Society, 334, pp. 138–152. doi: 10.1016/j.jconrel.2021.04.023.
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Dreckmann, T., Aipperspach, W., Pfleghar, K., Tröndle, J., Ernst, A., Huwyler, J., Ludwig, I.-S. and Luemkemann, J. (2020) “Assessment of Sensor Concepts for 100% In-Process Control of Low-Volume Aseptic Fill-Finish Processes”, PDA Journal of Pharmaceutical Science and Technology. Parenteral Drug Association (PDA), 74(6), pp. 660–673. doi: 10.5731/pdajpst.2019.011270.   edoc
Burkard, T., Rauch, M., Spoendlin, J., Prieto-Alhambra, D., Jick, S. S. and Meier, C. R. (2020) “Risk of hand osteoarthritis in new users of hormone replacement therapy: A nested case-control analysis”, Maturitas. Elsevier, 132, pp. 17–23. doi: 10.1016/j.maturitas.2019.11.006.   edoc
Davis, M. R., Nguyen, M.-V. H., Gintjee, T. J., Odermatt, A., Young, B. Y. and Thompson, G. R. (2020) “Management of posaconazole-induced pseudohyperaldosteronism”, Journal of Antimicrobial Chemotherapy. Oxford University Press, 75(12), pp. 3688–3693. doi: 10.1093/jac/dkaa366.   edoc
Ghanbarpour, A., Mahmoud, A. H. and Lill, M. A. (2020) “Instantaneous generation of protein hydration properties from static structures”, Communications Chemistry. Nature Publishing Group, 3, p. 188. doi: 10.1038/s42004-020-00435-5.   edoc
Mahmoud, A. H., Masters, M. R., Yang, Y. and Lill, M. A. (2020) “Elucidating the multiple roles of hydration for accurate protein-ligand binding prediction via deep learning”, Communications Chemistry. Nature Publishing Group, 3, p. 19. doi: 10.1038/s42004-020-0261-x.   edoc
Lüscher, S. C., Hersberger, K. E. and Brühwiler, L. D. (2020) “A survey on what pharmacists and physicians caring for nursing home residents expect of user-friendly lists of potentially inappropriate prescribing (PIP lists)”, Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen. Elsevier, 155, pp. 29–33. doi: 10.1016/j.zefq.2020.06.011.   edoc
Studer, H., Boeni, F., Messerli, M., Hersberger, K. E. and Lampert, M. L. (2020) “Clinical Pharmacy Activities in Swiss Hospitals: How Have They Evolved from 2013 to 2017?”, Pharmacy. MDPI, 8(1), p. 19. doi: 10.3390/pharmacy8010019.   edoc | Open Access
Imfeld-Isenegger, T. L., Pham, M. B. T., Stämpfli, D., Albert, V., Almanasreh, E., Moles, R., Chen, T. F. and Hersberger, K. E. (2020) “Medication Discrepancies in Community Pharmacies in Switzerland: Identification, Classification, and Their Potential Clinical and Economic Impact”, Pharmacy. MDPI, 8(1), p. 36. doi: 10.3390/pharmacy8010036.   edoc | Open Access
Rothen, J.-P., Rutishauser, J., Walter, P. N., Hersberger, K. E. and Arnet, I. (2020) “Oral intermittent vitamin D substitution: influence of pharmaceutical form and dosage frequency on medication adherence: a randomized clinical trial”, BMC Pharmacology & Toxicology. BioMed Central, 21(1), p. 51. doi: 10.1186/s40360-020-00430-5.   edoc
Soroury, S., Alilou, M., Gelbrich, T., Tabefam, M., Danton, O., Ebrahimi, S. N., Kaiser, M., Hamburger, M., Stuppner, H. and Farimani, M. M. (2020) “Unusual derivatives from Hypericum scabrum”, Scientific Reports. Nature Publishing Group, 10, p. 22181. doi: 10.1038/s41598-020-79305-y.   edoc
Holandino, C., de Oliveira Melo, M. N., Passos Oliveira, A., da Costa Batista, J. V., Alves Marques Capella, M., Garret, R., Grazi, M., Ramm, H., Dalla Torre, C., Schaller, G., Urech, K., Weissenstein, U. and Baumgartner, S. (2020) “Phytochemical analysis and in vitro anti-proliferative activity of Viscum album ethanolic extracts”, BMC Complementary Medicine and Therapies. BioMed Central, 20(1), p. 215. doi: 10.1186/s12906-020-02987-4.   edoc | Open Access
Haduch, A., Bromek, E., Rysz, M., Pukło, R., Papp, M., Gruca, P., Łasoń, M., Niemczyk, M. and Daniel, W. A. (2020) “The effects of agomelatine and imipramine on liver cytochrome P450 during chronic mild stress (CMS) in the rat”, Pharmacological Reports. Springer, 72(5), pp. 1271–1287. doi: 10.1007/s43440-020-00151-w.   edoc
Bonk, S., Hertel, J., Zacharias, H. U., Terock, J., Janowitz, D., Homuth, G., Nauck, M., Völzke, H., Meyer Zu Schwabedissen, H., Van der Auwera, S. and Grabe, H. J. (2020) “Vitamin D moderates the interaction between 5-HTTLPR and childhood abuse in depressive disorders”, Scientific reports, 10(1), p. 22394. doi: 10.1038/s41598-020-79388-7.   edoc
Patt, M., Gysi, J., Faresse, N., Cidlowski, J. A. and Odermatt, A. (2020) “Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211”, Molecular and cellular endocrinology. Elsevier, 518, p. 110873. doi: 10.1016/j.mce.2020.110873.   edoc | Open Access
Thompson, G. R., Surampudi, P. N. and Odermatt, A. (2020) “Gynecomastia and hypertension in a patient treated with posaconazole”, Clinical case reports. Wiley, 8(12), pp. 3157–3160. doi: 10.1002/ccr3.3376.   edoc | Open Access
Mayr, F., Möller, G., Garscha, U., Fischer, J., Rodríguez Castaño, P., Inderbinen, S. G., Temml, V., Waltenberger, B., Schwaiger, S., Hartmann, R. W., Gege, C., Martens, S., Odermatt, A., Pandey, A. V., Werz, O., Adamski, J., Stuppner, H. and Schuster, D. (2020) “Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction”, International Journal of Molecular Sciences. Molecular Diversity Preservation International, 21(19), p. 7102. doi: 10.3390/ijms21197102.   edoc | Open Access
Tsachaki, M., Strauss, P., Dunkel, A., Navrátilová, H., Mladenovic, N. and Odermatt, A. (2020) “Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration”, Cellular and Molecular Life Sciences. Springer, 77(6), pp. 1153–1175. doi: 10.1007/s00018-019-03227-w.   edoc | Open Access
Nguyen, M.-V. H., Davis, M. R., Wittenberg, R., McHardy, I., Baddley, J. W., Young, B. Y., Odermatt, A. and Thompson, G. R. (2020) “Posaconazole Serum Drug Levels Associated With Pseudohyperaldosteronism”, Clinical Infectious Diseases. Oxford University Press, 70(12), pp. 2593–2598. doi: 10.1093/cid/ciz741.   edoc
Gómez, C., Stücheli, S., Kratschmar, D. V., Bouitbir, J. and Odermatt, A. (2020) “Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples”, Metabolites. MDPI, 10(7), p. 282. doi: 10.3390/metabo10070282.   edoc | Open Access
Schulze, F., Wehner, J., Kratschmar, D. V., Makshana, V., Meier, D. T., Häuselmann, S. P., Dalmas, E., Thienel, C., Dror, E., Wiedemann, S. J., Traub, S., Nordmann, T. M., Rachid, L., De Baat, A., Rohm, T. V., Zhao, C., Odermatt, A., Böni-Schnetzler, M. and Donath, M. Y. (2020) “Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes”, Scientific Reports. Nature Publishing Group, 10(1), p. 3035. doi: 10.1038/s41598-020-59701-0.   edoc | Open Access
Beck, K. R., Thompson, G. R. and Odermatt, A. (2020) “Drug-induced endocrine blood pressure elevation”, Pharmacological Research. Elsevier, 154, p. 104311. doi: 10.1016/j.phrs.2019.104311.   edoc | Open Access
Hughes, S., Gumas, J., Lee, R., Rumano, M., Berger, N., Gautam, A. K., Sfyroera, G., Chan, A. L., Gnanaguru, G., Connor, K. M., Kim, B. J., Dunaief, J. L., Ricklin, D., Hajishengallis, G., Yancopoulou, D., Reis, E. S., Mastellos, D. C. and Lambris, J. D. (2020) “Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates”, Clinical Immunology. Elsevier, 214, p. 108391. doi: 10.1016/j.clim.2020.108391.   edoc
Olcina, M. M., Kim, R. K., Balanis, N. G., Li, C. G., von Eyben, R., Graeber, T. G., Ricklin, D., Stucki, M. and Giaccia, A. J. (2020) “Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis”, iScience. Cell Press, 23(10), p. 101594. doi: 10.1016/j.isci.2020.101594.   edoc
Don, C. G. and Smieško, M. (2020) “Deciphering Reaction Determinants of Altered-Activity CYP2D6 Variants by Well-Tempered Metadynamics Simulation and QM/MM Calculations”, Journal of Chemical Information and Modeling. American Chemical Society , 60(12), pp. 6642–6653. doi: 10.1021/acs.jcim.0c01091.   edoc
Potashkin, J., Huang, X., Becker, C., Chen, H., Foltynie, T. and Marras, C. (2020) “Understanding the links between cardiovascular disease and Parkinson’s disease”, Movement disorders : official journal of the Movement Disorder Society. Wiley-Liss, 35(1), pp. 55–74. doi: 10.1002/mds.27836.   edoc
Becker, C., Schwenkglenks, M., Frueh, M., Reich, O. and Meier, C. R. (2020) “Use of selective serotonin reuptake inhibitors, other antidepressant medication, and risk of cataract: a case-control study based on Swiss claims data”, European Journal of Clinical Pharmacology. Springer, 76(9), pp. 1329–1335. doi: 10.1007/s00228-020-02923-y.   edoc
Aicher, L. and Wilks, M. F. (2020) “From risk assessment to regulation”, in Colosio, C., Tsatsakis, A. M., Mandić-Rajćević, S., and Alegakis, A. (eds.) Exposure and Risk Assessment of Pesticide Use in Agriculture - Approaches, Tools and Advances. London: Academic Press, pp. 3–23. doi: 10.1016/B978-0-12-812466-6.00012-9.   edoc
Panajatovic, M. V., Singh, F., Roos, N. J., Duthaler, U., Handschin, C., Krähenbühl, S. and Bouitbir, J. (2020) “PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice”, Acta physiologica (Oxford, England). John Wiley & Sons, 228(4), p. e13402. doi: 10.1111/apha.13402.   edoc
Zhou, X., Bouitbir, J., Liechti, M. E., Krähenbühl, S. and Mancuso, R. V. (2020) “Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones ”, Cells, 9(4), p. 965. doi: 10.3390/cells9040965.   edoc
Zhou, X., Bouitbir, J., Liechti, M. E., Krähenbühl, S. and Mancuso, R. V. (2020) “Para; -Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells ”, International journal of molecular sciences. Multidisciplinary Digital Publishing Institute, 21(8), p. 2841. doi: 10.3390/ijms21082841.   edoc
Bouitbir, J., Alshaikhali, A., Panajatovic, M. V., Abegg, V. F., Paech, F. and Krähenbühl, S. (2020) “Mechanisms of Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in H9c2 Cells and Mice”, European cardiology. Radcliffe Cardiology, 15, p. e33. doi: 10.15420/ecr.2020.15.1.PO10.   edoc
Rudin, D., Schmutz, M., Roos, N. J., Bouitbir, J. and Krähenbühl, S. (2020) “Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis”, Biomedicines. MDPI AG, 8(7), p. 212. doi: 10.3390/biomedicines8070212.   edoc
Roos, N. J., Aliu, D., Bouitbir, J. and Krähenbühl, S. (2020) “Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells ”, Frontiers in pharmacology. Frontiers Media, 11, p. 944. doi: 10.3389/fphar.2020.00944.   edoc
Roos, N. J., Duthaler, U., Bouitbir, J. and Krähenbühl, S. (2020) “The uricosuric benzbromarone disturbs the mitochondrial redox homeostasis and activates the NRF2 signaling pathway in HepG2 cells ”, Free radical biology and medicine. Elsevier, 152, pp. 216–226. doi: 10.1016/j.freeradbiomed.2020.03.009.   edoc
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Smieško, M., Don, C. G., Meuwly, R., Kucsera, S. and Brüschweiler, B. J. (2018) “Large-scale in silico screening of compounds contained in printing inks for food packaging materials”, Toxicology Letters. Elsevier, 295, p. S96. doi: 10.1016/j.toxlet.2018.06.594.   edoc
Wimmersberger, D., Coulibaly, J. T., Schulz, J. D., Puchkov, M., Huwyler, J., N’Gbesso, Y., Hattendorf, J. and Keiser, J. (2018) “Efficacy and Safety of Ivermectin Against Trichuris trichiura in Preschool-aged and School-aged Children: A Randomized Controlled Dose-finding Trial”, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 67(8), pp. 1247–1255. doi: 10.1093/cid/ciy246.   edoc
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Yuan, X., Yang, M., Chen, X., Zhang, X., Sukhadia, S., Musolino, N., Bao, H., Chen, T., Xu, C., Wang, Q., Santoro, S., Ricklin, D., Hu, J., Lin, R., Yang, W., Li, Z., Qin, W., Zhao, A., Scholler, N. and Coukos, G. (2018) “Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy”, Cancer immunology, immunotherapy : CII, 67(2), pp. 329–339. doi: 10.1007/s00262-017-2101-0.   edoc
Ditter, D., Mahler, H.-C., Gohlke, L., Nieto, A., Roehl, H., Huwyler, J., Wahl, M. and Allmendinger, A. (2018) “Impact of Vial Washing and Depyrogenation on Surface Properties and Delamination Risk of Glass Vials”, Pharmaceutical research, 35(7), p. 146. doi: 10.1007/s11095-018-2421-6.   edoc
Boll, B., Josse, L., Heubach, A., Hochenauer, S., Finkler, C., Huwyler, J. and Koulov, A. V. (2018) “Impact of non-ideal analyte behavior on the separation of protein aggregates by asymmetric flow field-flow fractionation”, Journal of Separation Science, 2018; 41, pp. 2854–2864. doi: 10.1002/jssc.201701457.   edoc
Zihlmann, P., Silbermann, M., Sharpe, T., Jiang, X., Mühlethaler, T., Jakob, R. P., Rabbani, S., Sager, C. P., Frei, P., Pang, L., Maier, T. and Ernst, B. (2018) “KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists ”, Chemistry (Weinheim an der Bergstrasse, Germany), 24, pp. 1–10. doi: 10.1002/chem.201802599.   edoc
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Fischer, A., Don, C. G. and Smieško, M. (2018) “Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6”, Journal of chemical information and modeling. American Chemical Society, 58(9), pp. 1962–1975. doi: 10.1021/acs.jcim.8b00080.   edoc
Sánchez-Corral, P., Pouw, R. B., López-Trascasa, M. and Józsi, M. (2018) “Self-Damage Caused by Dysregulation of the Complement Alternative Pathway: Relevance of the Factor H Protein Family”, Frontiers in immunology, 9, p. 1607. doi: 10.3389/fimmu.2018.01607.   edoc
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Fritsche, E., Crofton, K. M., Hernandez, A. F., Hougaard Bennekou, S., Leist, M., Bal-Price, A., Reaves, E., Wilks, M. F., Terron, A., Solecki, R., Sachana, M. and Gourmelon, A. (2017) “OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes”, ALTEX. Springer Spektrum, 34(2), pp. 311–315. doi: 10.14573/altex.1701171.   edoc
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Haegler, P., Grünig, D., Berger, B., Terracciano, L., Krähenbühl, S. and Bouitbir, J. (2017) “Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice”, PLoS One. Public Library Science, 12(1), p. e0171026. doi: 10.1371/journal.pone.0171026.   edoc
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Hartung, T., FitzGerald, R. E., Jennings, P., Mirams, G. R., Peitsch, M. C., Rostami-Hodjegan, A., Shah, I., Wilks, M. F. and Sturla, S. J. (2017) “Systems Toxicology: Real World Applications and Opportunities”, Chemical research in toxicology. American Chemical Society (ACS) , 30(4), pp. 870–882. doi: 10.1021/acs.chemrestox.7b00003.   edoc | Open Access
Brueckner, D., Krähenbühl, S., Zuber, U., Bonkat, G. and Braissant, O. (2017) “An alternative sterility assessment for parenteral drug products using isothermal microcalorimetry”, Journal of Applied Microbiology, 123(3), pp. 773–779. doi: 10.1111/jam.13520.   edoc
Krähenbühl, S. and Pichler, W. J. (2017) “Medikamentöse Hepatopathien - Drug-induced liver injury”, Therapeutische Umschau. Hogrefe, 74(3), pp. 123–130. doi: 10.1024/0040-5930/a000895.   edoc
Paech, F., Bouitbir, J. and Krähenbühl, S. (2017) “Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis”, Frontiers in Pharmacology. Frontiers Media, 8, p. 367. doi: 10.3389/fphar.2017.00367.   edoc
Barda, B., Sayasone, S., Phongluxa, K., Xayavong, S., Keoduangsy, K., Odermatt, P., Puchkov, M., Huwyler, J., Hattendorf, J. and Keiser, J. (2017) “Efficacy of Moxidectin Versus Ivermectin Against Strongyloides stercoralis Infections: A Randomized, Controlled Noninferiority Trial”, Clinical Infectious Diseases. Oxford University Press, 65(2), pp. 276–281. doi: 10.1093/cid/cix278.   edoc
Krähenbühl, S. (2017) “Importance of the skeletal muscle carnitine stores in fuel selection”, The Journal of Physiology. Wiley, 595(17), pp. 5727–5728. doi: 10.1113/JP274755.   edoc
Blaser, L., Hassna, H., Hofmann, S., Holbro, A., Haschke, M., Rätz Bravo, A., Zeller, A., Krähenbühl, S. and Taegtmeyer, A. (2017) “Leucopenia associated with metamizole: a case-control study”, Swiss medical weekly. EMH Swiss Medical Publishers, 147, p. w14438. doi: 10.4414/smw.2017.14438.   edoc
Brueckner, D., Solokhina, A., Krähenbühl, S. and Braissant, O. (2017) “A combined application of tunable diode laser absorption spectroscopy and isothermal micro-calorimetry for calorespirometric analysis”, Journal of Microbiological Methods. Elsevier, 139, pp. 210–214. doi: 10.1016/j.mimet.2017.06.012.   edoc
Drago, S., Imboden, R., Schlatter, P., Buylaert, M., Krähenbühl, S. and Drewe, J. (2017) “Pharmacokinetics of Transdermal Etofenamate and Diclofenac in Healthy Volunteers”, Basic and Clinical Pharmacology and Toxicology. Wiley, 121(5), pp. 423–429. doi: 10.1111/bcpt.12818.   edoc
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Jiménez-Canino, R., Lorenzo-Díaz, F., Odermatt, A., Bailey, M. A., Livingstone, D. E. W., Jaisser, F., Farman, N. and Alvarez de la Rosa, D. (2017) “11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation”, Endocrinology. Oxford University Press, 158(11), pp. 4047–4063. doi: 10.1210/en.2017-00440.   edoc
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Engeli, R. T., Tsachaki, M., Hassan, H. A., Sager, C. P., Essawi, M. L., Gad, Y. Z., Kamel, A. K., Mazen, I. and Odermatt, A. (2017) “Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients”, The journal of sexual medicine, 14(9), pp. 1165–1174. doi: 10.1016/j.jsxm.2017.07.006.   edoc
Knöpfel, T., Pastor-Arroyo, E. M., Schnitzbauer, U., Kratschmar, D. V., Odermatt, A., Pellegrini, G., Hernando, N. and Wagner, C. A. (2017) “The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction”, Scientific reports, 7(1), p. 11018. doi: 10.1038/s41598-017-10390-2.   edoc
Dolder, P. C., Strajhar, P., Vizeli, P., Hammann, F., Odermatt, A. and Liechti, M. E. (2017) “Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects”, Frontiers in pharmacology, 8, p. 617. doi: 10.3389/fphar.2017.00617.   edoc
van Beek, A. E., Pouw, R. B., Brouwer, M. C., van Mierlo, G., Geissler, J., Ooijevaar-de Heer, P., de Boer, M., van Leeuwen, K., Rispens, T., Wouters, D. and Kuijpers, T. W. (2017) “Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma”, Frontiers in Immunology. Frontiers Media, 8, p. 1328. doi: 10.3389/fimmu.2017.01328.   edoc
Engeli, R. T., Rohrer, S. R., Vuorinen, A., Herdlinger, S., Kaserer, T., Leugger, S., Schuster, D. and Odermatt, A. (2017) “Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases”, International Journal of Molecular Sciences, 18(9), pp. 1–13. doi: 10.3390/ijms18092007.   edoc | Open Access
Aghagolzadeh, P., Radpour, R., Bachtler, M., van Goor, H., Smith, E. R., Lister, A., Odermatt, A., Feelisch, M. and Pasch, A. (2017) “Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation”, Atherosclerosis, 265, pp. 78–86. doi: 10.1016/j.atherosclerosis.2017.08.012.   edoc
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Cramer, J., Schiebel, J., Wulsdorf, T., Grohe, K., Najbauer, E. E., Ehrmann, F. R., Radeva, N., Zitzer, N., Linne, U., Linser, R., Heine, A. and Klebe, G. (2017) “A False-Positive Screening Hit in Fragment-Based Lead Discovery: Watch out for the Red Herring”, Angewandte Chemie (International Edition), 56(7), pp. 1908–1913. doi: 10.1002/anie.201609824.   edoc
Cramer, J., Krimmer, S. G., Heine, A. and Klebe, G. (2017) “Paying the Price of Desolvation in Solvent-Exposed Protein Pockets: Impact of Distal Solubilizing Groups on Affinity and Binding Thermodynamics in a Series of Thermolysin Inhibitors”, Journal of Medicinal Chemistry, 60(13), pp. 5791–5799. doi: 10.1021/acs.jmedchem.7b00490.   edoc


Moradi-Afrapoli, F., Oufir, M., Walter, F. R., Deli, M. A., Smieško, M., Zabela, V., Butterweck, V. and Hamburger, M. (2016) “Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro BBB and intestinal drug permeability studies”, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 264–274. doi: 10.1016/j.jpba.2016.05.039.   edoc
Jähne, E. A., Sampath, C., Butterweck, V., Hamburger, M. and Oufir, M. (2016) “Development and full validation of an UPLC-MS/MS method for the quantification of indirubin in rat plasma”, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 247–252. doi: 10.1016/j.jpba.2016.05.018.   edoc
Kettiger, H., Québatte, G., Perrone, B. and Huwyler, J. (2016) “Interactions between silica nanoparticles and phospholipid membranes”, Biochimica et biophysica acta. Elsevier, 1858(9), pp. 2163–2170. doi: 10.1016/j.bbamem.2016.06.023.   edoc
Hussner, J., Sünwoldt, J., Seibert, I., Gliesche, D. G. and Meyer zu Schwabedissen, H. E. (2016) “Pimecrolimus increases the expression of interferon-inducible genes that modulate human coronary artery cells proliferation”, European Journal of Pharmacology. Elsevier, 784, pp. 137–146. doi: 10.1016/j.ejphar.2016.05.020.   edoc
Buck, J., Huwyler, J., Kühl, P. and Dischinger, A. (2016) “Pediatric Dispersible Tablets: a Modular Approach for Rapid Prototyping”, Pharmaceutical research. Plenum Press, 33(8), pp. 2043–2055. doi: 10.1007/s11095-016-1946-9.   edoc
Preisig, D., Roth, R., Tognola, S., Varum, F. J. O., Bravo, R., Cetinkaya, Y., Huwyler, J. and Puchkov, M. (2016) “Mucoadhesive microparticles for local treatment of gastrointestinal diseases”, European journal of pharmaceutics and biopharmaceutics. Elsevier, 105, pp. 156–165. doi: 10.1016/j.ejpb.2016.06.009.   edoc
Gliesche, D. G., Hussner, J., Witzigmann, D., Porta, F., Glatter, T., Schmidt, A., Huwyler, J. and Meyer Zu Schwabedissen, H. E. (2016) “Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries”, Molecular Pharmaceutics. American Chemical Society, 13(7), pp. 2290–2300. doi: 10.1021/acs.molpharmaceut.6b00033.   edoc
Bischoff, T., Vogl, C. R., Ivemeyer, S., Klarer, F., Meier, B., Hamburger, M. and Walkenhorst, M. (2016) “Plant and natural product based household remedies manufactured and used by farmers of six central Swiss cantons to treat livestock”, Livestock science. Elsevier, 189, pp. 110–125. doi: 10.1016/j.livsci.2016.05.003.   edoc
Hu, Z., Wahl, J., Hamburger, M. and Vedani, A. (2016) “Molecular mechanisms of endocrine and metabolic disruption: An in silico study on antitrypanosomal natural products and some derivatives”, Toxicology Letters. Elsevier, 252, pp. 29–41. doi: 10.1016/j.toxlet.2016.04.013.   edoc
Eigenmann, D. E., Dürig, C., Jähne, E. A., Smieško, M., Culot, M., Gosselet, F., Cecchelli, R., Cederberg Helms, H. C., Brodin, B., Wimmer, L., Mihovilovic, M. D., Hamburger, M. and Oufir, M. (2016) “In vitro blood-brain barrier permeability predictions of piperine analogues with GABAA receptor modulating properties”, European Journal of Pharmaceutics and Biopharmaceutics. Elsevier, 103, pp. 118–126. doi: 10.1016/j.ejpb.2016.03.029.   edoc
Witzigmann, D., Quagliata, L., Schenk, S. H., Quintavalle, C., Terracciano, L. M. and Huwyler, J. (2016) “Variable asialoglycoprotein-receptor 1 expression in liver disease: Implications for therapeutic intervention”, Hepatology research . Blackwell, 46(7), pp. 686–696. doi: 10.1111/hepr.12599.   edoc
Eberle, V. A., Häring, A., Schoelkopf, J., Gane, P. A. C., Huwyler, J. and Puchkov, M. (2016) “In silico and in vitro methods to optimize the performance of experimental gastroretentive floating mini-tablets”, Drug development and industrial pharmacy. Informa Healthcare, 42(5), pp. 808–817. doi: 10.3109/03639045.2015.1078350.   edoc
Canonica, J., Sergi, C., Maillard, M., Klusonova, P., Odermatt, A., Koesters, R., Loffing-Cueni, D., Loffing, J., Rossier, B., Frateschi, S. and Hummler, E. (2016) “Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype”, Pflügers Archiv : European journal of physiology. Springer, 468(5), pp. 895–908. doi: 10.1007/s00424-015-1785-2.   edoc
Mani, O., Nashev, L. G., Livelo, C., Baker, M. E. and Odermatt, A. (2016) “Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone”, The Journal of steroid biochemistry and molecular biology. Elsevier, 159, pp. 31–40. doi: 10.1016/j.jsbmb.2016.02.017.   edoc
Riede, J., Poller, B., Umehara, K.- ichi, Huwyler, J. and Camenisch, G. (2016) “New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data”, European journal of pharmaceutical sciences. Elsevier, 86, pp. 96–102. doi: 10.1016/j.ejps.2016.02.022.   edoc
Odermatt, A., Strajhar, P. and Engeli, R. T. (2016) “Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools”, The Journal of steroid biochemistry and molecular biology. Elsevier, 158, pp. 9–21. doi: 10.1016/j.jsbmb.2016.01.009.   edoc
Grabe, H. J., Wittfeld, K., Van der Auwera, S., Janowitz, D., Hegenscheid, K., Habes, M., Homuth, G., Barnow, S., John, U., Nauck, M., Völzke, H., Meyer zu Schwabedissen, H. E., Freyberger, H. J. and Hosten, N. (2016) “Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample”, Human brain mapping. Wiley-Liss, 37(4), pp. 1602–1613. doi: 10.1002/hbm.23123.   edoc
Bloechliger, M., Ceschi, A., Rüegg, S., Kupferschmidt, H., Krähenbühl, S., Jick, S. S., Meier, C. R. and Bodmer, M. (2016) “Risk of Seizures Associated with Antidepressant Use in Patients with Depressive Disorder: Follow-up Study with a Nested Case-Control Analysis Using the Clinical Practice Research Datalink”, Drug Safety . Springer, 39(4), pp. 307–321. doi: 10.1007/s40264-015-0363-z.   edoc
Seliger, C., Meier, C. R., Jick, S. S., Uhl, M., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) “Use of cardiac glycosides and risk of glioma”, Journal of Neuro-Oncology . Springer Science+Business Media B.V, 127(2), pp. 321–328. doi: 10.1007/s11060-015-2036-2.   edoc
Ramming, T., Kanemura, S., Okumura, M., Inaba, K. and Appenzeller-Herzog, C. (2016) “Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover”, Redox biology. Elsevier, 7, pp. 14–20. doi: 10.1016/j.redox.2015.11.004.   edoc
Strajhar, P., Schmid, Y., Liakoni, E., Dolder, P. C., Rentsch, K. M., Kratschmar, D. V., Odermatt, A. and Liechti, M. E. (2016) “Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects”, Journal of Neuroendocrinology. Wiley, 28(3), p. 12374. doi: 10.1111/jne.12374.   edoc | Open Access
Coqueiro, A., Choi, Y. H., Verpoorte, R., Sankar Gupta, K. B. S., De Mieri, M., Hamburger, M., Marx Young, M. C., Stapleton, P., Gibbons, S. and da Silva Bolzani, V. (2016) “Anti-staphylococcal prenylated acylphoroglucinol and xanthones from Kielmeyera variabilis (Clusiaceae)”, Journal of natural products. American Society of Pharmacognosy, 79(3), pp. 470–476. doi: 10.1021/acs.jnatprod.5b00858.   edoc
Eigenmann, D. E., Jähne, E. A., Smiesko, M., Hamburger, M. and Oufir, M. (2016) “Validation of an immortalized human (hBMEC) in vitro blood-brain barrier model”, Analytical and Bioanalytical Chemistry. Springer, 408(8), pp. 2095–2107. doi: 10.1007/s00216-016-9313-6.   edoc
Seliger, C., Ricci, C., Meier, C. R., Bodmer, M., Jick, S. S., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) “Diabetes, use of antidiabetic drugs, and the risk of glioma”, Neuro-Oncology. Oxford University Press, 18(3), pp. 340–349. doi: 10.1093/neuonc/nov100.   edoc | Open Access
Bornand, D., Toovey, S., Jick, S. S. and Meier, C. R. (2016) “The risk of new onset depression in association with influenza - a population-based observational study”, Brain, Behavior and Immunity . Elsevier, 53, pp. 131–137. doi: 10.1016/j.bbi.2015.12.005.   edoc
Requena, G., Huerta, C., Gardarsdottir, H., Logie, J., González-González, R., Abbing-Karahagopian, V., Miret, M., Schneider, C., Souverein, P. C., Webb, D., Afonso, A., Boudiaf, N., Martin, E., Oliva, B., Alvarez, A., De Groot, M. C. H., Bate, A., Johansson, S., Schlienger, R., Reynolds, R., Klungel, O. H. and de Abajo, F. J. (2016) “Hip/femur fractures associated with the use of benzodiazepines (anxiolytics, hypnotics and related drugs): a methodological approach to assess consistencies across databases from the PROTECT-EU project”, Pharmacoepidemiology and drug safety. Wiley, 25(1), pp. 66–78. doi: 10.1002/pds.3816.   edoc
Huerta, C., Abbing-Karahagopian, V., Requena, G., Oliva, B., Alvarez, Y., Gardarsdottir, H., Miret, M., Schneider, C., Gil, M., Souverein, P. C., De Bruin, M. L., Slattery, J., De Groot, M. C. H., Hesse, U., Rottenkolber, M., Schmiedl, S., Montero, D., Bate, A., Ruigomez, A., García-Rodríguez, L. A., Johansson, S., de Vries, F., Schlienger, R. G., Reynolds, R. F., Klungel, O. H. and de Abajo, F. J. (2016) “Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project”, Pharmacoepidemiology and drug safety. John Wiley, 25(1), pp. 56–65. doi: 10.1002/pds.3825.   edoc
Spoendlin, J., Karatas, G., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) “Rosacea in Patients with Ulcerative Colitis and Crohn’s Disease: a Population-based Case-control Study”, Inflammatory Bowel Diseases. Lippincott Williams & Wilkins, 22(3), pp. 680–687. doi: 10.1097/MIB.0000000000000644.   edoc
Corradi, E., De Mieri, M., Cadisch, L., Abbet, C. ., Hamburger, M. and Potterat, O. (2016) “New Acylated Flavonol Glycosides and a Phenolic Profile of Pritzelago alpina, a Forgotten Edible Alpine Plant ”, Chemistry & Biodiversity. Helvetica Chimica Acta, 13(2), pp. 188–197. doi: 10.1002/cbdv.201500353.   edoc
Ríos Quiroz, A., Lamerz, J., De Cunha, T., Boillon, A., Adler, M., Finkler, C., Huwyler, J., Schmidt, R., Mahler, H.-C. and Koulov, A. V. (2016) “Factors Governing the Precision of Subvisible Particle Measurement Methods - A Case Study with a Low-Concentration Therapeutic Protein Product in a Prefilled Syringe”, Pharmaceutical research. Springer, 33(2), pp. 450–461. doi: 10.1007/s11095-015-1801-4.   edoc
Wilson, J. C., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) “Inflammatory Bowel Disease and the Risk of Autoimmune Diseases”, Journal of Crohn’s and Colitis. Elsevier, 10(2), pp. 186–193. doi: 10.1093/ecco-jcc/jjv193.   edoc
Mathaes, R., Mahler, H.-C., Buettiker, J.-P., Roehl, H., Lam, P., Brown, H., Luemkemann, J., Adler, M., Huwyler, J., Streubel, A. and Mohl, S. (2016) “The pharmaceutical vial capping process; Container closure systems, capping equipment, regulatory framework, and seal quality tests”, European journal of pharmaceutics and biopharmaceutics. Elsevier, 99, pp. 54–64. doi: 10.1016/j.ejpb.2015.11.016.   edoc
Rizner, T. L., Sasano, H., Choi, M. H., Odermatt, A. and Adamski, J. (2016) “Recommendations for description and validation for antibodies for research use”, The journal of steroid biochemistry and molecular biology. Pergamon, 156, pp. 40–42. doi: 10.1016/j.jsbmb.2015.11.021.   edoc
Messerli, M., Maes, K. A., Hersberger, K. E. and Lampert, M. L. (2016) “Mapping clinical pharmacy practice in Swiss hospitals: a cross-sectional study”, European Journal of Hospital Pharmacy. BMJ Group, 23(6), pp. 314–319. doi: 10.1136/ejhpharm-2015-000868.   edoc | Open Access
Hersberger, K. E. and Messerli, M. (2016) “Development of Clinical Pharmacyx in Switzerland: Involvement of Community Pharmacists in Care for Older Patients”, Drugs & Aging . Springer, 33(3), pp. 205–211. doi: 10.1007/s40266-016-0353-6.   edoc
Uddin, M. J., Groenwold, R. H. H., de Boer, A., Afonso, A. S. M., Primatesta, P., Becker, C., Belitser, S. V., Hoes, A. W., Roes, K. C. B. and Klungel, O. H. (2016) “Evaluating different physician’s prescribing preference based instrumental variables in two primary care databases: a study of inhaled long-acting beta2-agonist use and the risk of myocardial infarction”, Pharmacoepidemiology and Drug Safety. Wiley, 25(Supplement 1), pp. 132–141. doi: 10.1002/pds.3860.   edoc
Afonso, A., Schmiedl, S., Becker, C., Tcherny-Lessenot, S., Primatesta, P., Plana, E., Souverein, P., Wang, Y., Korevaar, J. C., Hasford, J., Reynolds, R., de Groot, M. C. H., Schlienger, R., Klungel, O. and Rottenkolber, M. (2016) “A methodological comparison of two European primary care databases and replication in a US claims database: inhaled long-acting beta-2-agonists and the risk of acute myocardial infarction”, European Journal of Clinical Pharmacology. Springer, 72(9), pp. 1105–1116. doi: 10.1007/s00228-016-2071-8.   edoc
Rysz, M., Bromek, E., Haduch, A., Liskova, B., Wójcikowski, J. and Daniel, W. A. (2016) “The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11”, Biochemical Pharmacology. Elsevier, 112, pp. 82–89. doi: 10.1016/j.bcp.2016.04.017.   edoc
Rysz, M., Bromek, E. and Daniel, W. A. (2016) “Activation of brain serotonergic system by repeated intracerebral administration of 5-hydroxytryptophan (5-HTP) decreases the expression and activity of liver cytochrome P450”, Biochemical Pharmacology. Elsevier, 99, pp. 113–122. doi: 10.1016/j.bcp.2015.11.014.   edoc
Kindo, M., Gerelli, S., Bouitbir, J., Hoang Minh, T., Charles, A.-L., Mazzucotelli, J.-P., Zoll, J., Piquard, F. and Geny, B. (2016) “Left Ventricular Transmural Gradient in Mitochondrial Respiration Is Associated with Increased Sub-Endocardium Nitric Oxide and Reactive Oxygen Species Productions”, Frontiers in Physiology. Frontiers Media, 7, p. 331. doi: 10.3389/fphys.2016.00331.   edoc


Kettiger, H., Karaman, D. S., Schiesser, L., Rosenholm, J. M. and Huwyler, J. (2015) “Comparative safety evaluation of silica-based particles”, Toxicology in vitro. Elsevier, 30(1), pp. 355–363. doi: 10.1016/j.tiv.2015.09.030.   edoc
Moghadam, S. E., Ebrahimi, S. N., Gafner, F., Ochola, J. B., Marubu, R. M., Lwande, W., Frei Haller, B., Salehi, P. and Hamburger, M. (2015) “Metabolite profiling for caffeic acid oligomers in Satureja biflora”, Industrial Crops and Products. Elsevier, 76, pp. 892–899. doi: 10.1016/j.indcrop.2015.07.059.   edoc
Arnet, I., Altermatt, M., Roggo, Y. and Schnetzler, G. (2015) “Pharmaceutical quality of eight generics of ceftriaxone preparation for injection in Eastern Asia”, Journal of chemotherapy . Taylor & Francis Group, 27(6), pp. 337–342. doi: 10.1179/1973947814Y.0000000208.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) “Association of hormone therapy and incident gout: population-based case-control study”, Menopause. Lippincott, 22(12), pp. 1335–1342. doi: 10.1097/GME.0000000000000474.   edoc
Favre-Godal, Q., Dorsaz, S., Queiroz, E. F., Marcourt, L., Ebrahimi, S. N., Allard, P.-M., Voinesco, F., Hamburger, M., Gupta, M. P., Gindro, K., Sanglard, D. and Wolfender, J.-L. (2015) “Identification of novel anti-Candida cassane type diterpenes from the roots bark of Swartzia simplex (Sw.) Spreng”, Journal of Natural Products. American Chemical Society, 78(12), pp. 2994–3004. doi: 10.1021/acs.jnatprod.5b00744.   edoc
Arnet, I., Seidling, H. M. and Hersberger, K. E. (2015) “Unerwünschte Arzneimittelwirkungen in der Offizinapotheke”, Therapeutische Umschau. Hans Huber, 72(11/12), pp. 687–692. doi: 10.1024/0040-5930/a000738.   edoc
Folzer, E., Khan, T., Schmidt, R., Finkler, C., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) “Determination of the Density of Protein Particles Using a Suspended Microchannel Resonator”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(12), pp. 4034–4040. doi: 10.1002/jps.24635.   edoc
Boll, B., Folzer, E., Finkler, C., Huwyler, J., Mahler, H.-C., Schmidt, R. and Koulov, A. V. (2015) “Comparative Evaluation of Two Methods for Preparative Fractionation of Proteinaceous Subvisible Particles-Differential Centrifugation and FACS”, Pharmaceutical research. Springer, 32(12), pp. 3952–3964. doi: 10.1007/s11095-015-1755-6.   edoc
Kaserer, T., Beck, K., Akram, M., Odermatt, A. and Schuster, D. (2015) “Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases”, Molecules. MDPI, 20(12), pp. 22799–22832. doi: 10.3390/molecules201219880.   edoc
Shelton, L. M., Lister, A., Walsh, J., Jenkins, R. E., Wong, M. H. L., Rowe, C., Ricci, E., Ressel, L., Fang, Y., Demougin, P., Vukojevic, V., O’Neill, P. M., Goldring, C. E., Kitteringham, N. R., Park, B. K., Odermatt, A. and Copple, I. M. (2015) “Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney”, Kidney international. Springer, 88(6), pp. 1261–1273. doi: 10.1038/ki.2015.286.   edoc
Becker, C., Wilson, J. C., Jick, S. S. and Meier, C. R. (2015) “Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: a case-control analysis”, International journal of cancer. Alan R. Liss, 137(10), pp. 2424–2431. doi: 10.1002/ijc.29601.   edoc
Seibert, J. K., Quagliata, L., Quintavalle, C., Hammond, T. G., Terracciano, L. and Odermatt, A. (2015) “A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer”, Cancer medicine. Wiley, 4(11), pp. 1717–1729. doi: 10.1002/cam4.517.   edoc
Di Chiara, M., Glaudemans, B., Loffing-Cueni, D., Odermatt, A., Al-Hasani, H., Devuyst, O., Faresse, N. and Loffing, J. (2015) “Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney”, American journal of physiology. Gastrointestinal and liver physiology. American Physiological Society, 309(9), pp. F779-F790. doi: 10.1152/ajprenal.00139.2015.   edoc
Becker, C., Jick, S. S., Meier, C. R. and Bodmer, M. (2015) “No evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: a case-control study”, BMC Cancer. BioMed Central, 15, p. 719. doi: 10.1186/s12885-015-1719-6.   edoc
Haegler, P., Grünig, D., Berger, B., Krähenbühl, S. and Bouitbir, J. (2015) “Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: a cell model for idiosyncratic toxicity”, Toxicology. Elsevier, 336, pp. 48–58. doi: 10.1016/j.tox.2015.07.015.   edoc
Imfeld, P., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) “Benzodiazepine Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case-Control Analysis”, Drug safety. Adis International, 38(10), pp. 909–919. doi: 10.1007/s40264-015-0319-3.   edoc
Glanzmann, C., Frey, B., Meier, C. R. and Vonbach, P. (2015) “Analysis of medication prescribing errors in critically ill children”, European journal of pediatrics. Springer, 174(10), pp. 1347–1355. doi: 10.1007/s00431-015-2542-4.   edoc
Allmendinger, A., Mueller, R., Huwyler, J., Mahler, H.-C. and Fischer, S. (2015) “Sterile Filtration of Highly Concentrated Protein Formulations: Impact of Protein Concentration, Formulation Composition, and Filter Material”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(10), pp. 3319–3329. doi: 10.1002/jps.24561.   edoc
Farimani, M. M., Bahadori, M. B., Koulaei, S. A., Salehi, P., Ebrahimi, S. N., Khavasi, H. R. and Hamburger, M. (2015) “New ursane triterpenoids from Salvia urmiensis Bunge: absolute configuration and anti-proliferative activity”, Fitoterapia. Elsevier, 106, pp. 1–6. doi: 10.1016/j.fitote.2015.07.017.   edoc
Du, K., De Mieri, M., Neuburger, M., Zietsman, P. C., Marston, A., van Vuuren, S. F., Ferreira, D., Hamburger, M. and van der Westhuizen, J. H. (2015) “Labdane and clerodane diterpenes from Colophospermum mopane”, Journal of Natural Products. American Chemical Society, 78(10), pp. 2494–2504. doi: 10.1021/acs.jnatprod.5b00729.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) “Poorly controlled type 2 diabetes mellitus is associated with a decreased risk of incident gout: a population-based case-control study”, Annals of the rheumatic diseases. British Medical Association, 74(9), pp. 1651–1658. doi: 10.1136/annrheumdis-2014-205337.   edoc
Werk, T., Huwyler, J., Hafner, M., Luemkemann, J. and Mahler, H.-C. (2015) “An Impedance-Based Method to Determine Reconstitution Time for Freeze-Dried Pharmaceuticals”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2948–2955. doi: 10.1002/jps.24443.   edoc
Folzer, E., Diepold, K., Bomans, K., Finkler, C., Schmidt, R., Bulau, P., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) “Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule”, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2824–2831. doi: 10.1002/jps.24509.   edoc
Kunze, A., Poller, B., Huwyler, J. and Camenisch, G. (2015) “Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins”, Drug Metabolism and Personalized Therapy. de Gruyter, 30(3), pp. 175–188. doi: 10.1515/dmdi-2015-0003.   edoc
Hussner, J., Begung, R., Boettcher, K., Gliesche, D. G., Prestin, K. and Meyer zu Schwabedissen, H. E. (2015) “Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery”, Vascular Pharmacology . Elsevier, 72, pp. 25–34. doi: 10.1016/j.vph.2015.06.006.   edoc
Moridi Farimani, M., Abbas-Mohammadi, M., Esmaeili, M.-A., Salehi, P., Nejad-Ebrahimi, S., Sonboli, A. and Hamburger, M. (2015) “Seco-ursane type triterpenoids from Salvia urmiensis with apoptosis-inducing activity”, Planta medica. Thieme, 81(14), pp. 1290–1295. doi: 10.1055/s-0035-1546256.   edoc
Wilson, J. C., Toovey, S., Jick, S. S. and Meier, C. R. (2015) “Previously diagnosed influenza infections and the risk of developing epilepsy”, Epidemiology and infection. Cambridge University Press, 143(11), pp. 2408–2415. doi: 10.1017/S0950268814003380.   edoc
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