2020

Lizák, B., Birk, J., Zana, M., Kosztyi, G., Kratschmar, D. V., Odermatt, A., Zimmermann, R., Geiszt, M., Appenzeller-Herzog, C. and Bánhegyi, G. (2020) ‘Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione’, BMC Biology. BioMed Central, 18(1), p. 19. doi: 10.1186/s12915-020-0749-y.   edoc | Open Access
Einfalt, T., Garni, M., Witzigmann, D., Sieber, S., Baltisberger, N., Huwyler, J., Meier, W. and Palivan, C. (2020) ‘Bioinspired Molecular Factories with Architecture and In Vivo Functionalities as Cell Mimics’, Advanced Science. Wiley, 7(4), p. 1901923. doi: 10.1002/advs.201901923.   edoc | Open Access
Dreckmann, T., Ludwig, I.-S., Boeuf, J., Lümkemann, J. and Huwyler, J. (2020) ‘Low Volume Aseptic Filling: Impact of Pump Systems on Shear Stress’, European Journal of Pharmaceutics and Biopharmaceutics, 147, pp. 10-18. doi: 10.1016/j.ejpb.2019.12.006.   
Lederer, A.-K., Maul-Pavicic, A., Hannibal, L., Hettich, M., Steinborn, C., Gründemann, C., Zimmermann-Klemd, A. M., Müller, A., Sehnert, B., Salzer, U., Klein, R., Voll, R. E., Samstag, Y. and Huber, R. (2020) ‘Vegan diet reduces neutrophils, monocytes and platelets related to branched-chain amino acids - A randomized, controlled trial’, Clinical nutrition (Edinburgh, Scotland), p. Epub ahead of print. doi: 10.1016/j.clnu.2020.02.011.   
Burkard, T., Rauch, M., Spoendlin, J., Prieto-Alhambra, D., Jick, S. S. and Meier, C. R. (2020) ‘Risk of hand osteoarthritis in new users of hormone replacement therapy: A nested case-control analysis’, Maturitas, 132, pp. 17-23. doi: 10.1016/j.maturitas.2019.11.006.   
Fischer, A. and Smieško, M. (2020) ‘Allosteric Binding Sites On Nuclear Receptors: Focus On Drug Efficacy and Selectivity’, International journal of molecular sciences, 21(2), p. 534. doi: 10.3390/ijms21020534.   
Sedighi, M., Rahimi, F., Shahbazi, M.-A., Rezayan, A. H., Kettiger, H., Einfalt, T., Huwyler, J. and Witzigmann, D. (2020) ‘Controlled Tyrosine Kinase Inhibitor Delivery to Liver Cancer Cells by Gate-Capped Mesoporous Silica Nanoparticles’, ACS Applied Bio Materials, 3, pp. 239-251. doi: 10.1021/acsabm.9b00772.   
Chilczuk, T., Steinborn, C., Breinlinger, S., Zimmermann-Klemd, A. M., Huber, R., Enke, H., Enke, D., Niedermeyer, T. H. J. and Gründemann, C. (2020) ‘Hapalindoles from the Cyanobacterium Hapalosiphon sp. Inhibit T Cell Proliferation’, Planta medica, 86(2), pp. 96-103. doi: 10.1055/a-1045-5178.   
Inderbinen, S. G., Engeli, R. T., Rohrer, S. R., Di Renzo, E., Aengenheister, L., Buerki-Thurnherr, T. and Odermatt, A. (2020) ‘Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α’, Toxicology letters, 322, pp. 39-49. doi: 10.1016/j.toxlet.2020.01.001.   
Häuser, C., Goldbach, P., Huwyler, J., Friess, W. and Allmendinger, A. (2020) ‘Excipients for Room Temperature Stable Freeze-Dried Monoclonal Antibody Formulations’, Journal of Pharmaceutical Sciences, 109, pp. 807-817. doi: 10.1016/j.xphs.2019.10.016.   
Schuster, J., Koulov, A., Mahler, H.-C., Detampel, P., Huwyler, J., Singh, S. and Mathaes, R. (2020) ‘In Vivo Stability of Therapeutic Proteins’, Pharmaceutical research, 37(2), p. 23. doi: 10.1007/s11095-019-2689-1.   
Ehrsam, D., Sieber, S., Oufir, M., Porta, F., Hamburger, M., Huwyler, J. and Meyer zu Schwabedissen, H. E. (2020) ‘Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9’, Bioconjugate Chemistry, 31, pp. 781-793. doi: 10.1021/acs.bioconjchem.9b00865.   
Wagner-Hattler, L., Québatte, G., Keiser, J., Schoelkopf, J., Schlepütz, C. M., Huwyler, J. and Puchkov, M. (2020) ‘Study of drug particle distributions within mini-tables using synchrotron X-ray microtomography and superpixel image clustering’, International Journal of Pharmaceutics, 573, p. 118827. doi: 10.1016/j.ijpharm.2019.118827.   
Schittny, A., Huwyler, J. and Puchkov, M. (2020) ‘Mechanisms of increased bioavailability through amorphous solid dispersions: a review’, Drug delivery, 27(1), pp. 110-127. doi: 10.1080/10717544.2019.1704940.   
Walkenhorst, M., Leiber, F., Maeschli, A., Kapp, A. N., Spengler‐Neff, A., Faleschini, M. T., Garo, E., Hamburger, M., Potterat, O., Mayer, P., Graf-Schiller, S. and Bieber, A. (2020) ‘A multicomponent herbal feed additive improves somatic cell counts in dairy cows ‐ a two stage, multicentre, placebo‐controlled long‐term on‐farm trial’, Journal of Animal Physiology and Animal Nutrition, 104, pp. 439-452.   
Beck, K. R., Telisman, L., van Koppen, C. J., Thompson, G. R. and Odermatt, A. (2020) ‘Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals’, The Journal of steroid biochemistry and molecular biology, 199, p. 105605. doi: 10.1016/j.jsbmb.2020.105605.   
Gründemann, C., Reinhardt, J. K. and Lindequist, U. (2020) ‘European medicinal mushrooms: Do they have potential for modern medicine? - An update’, Phytomedicine : international journal of phytotherapy and phytopharmacology, 66, p. 153131. doi: 10.1016/j.phymed.2019.153131.   
Schittny, A., Philipp-Bauer, S., Detampel, P., Huwyler, J. and Puchkov, M. (2020) ‘Mechanistic insights into effect of surfactants on oral bioavailability of amorphous solid dispersions’, Journal of controlled release, 320, pp. 214-225. doi: 10.1016/j.jconrel.2020.01.031.   
Mertenat, D., Dal Cero, M., Vogl, C. R., Ivemeyer, S., Meier, B., Maeschli, A., Hamburger, M. and Wlkenhorst, M. (2020) ‘Ethnoveterinary knowledge of farmers in bilingual regions of Switzerland - is there potential to extend veterinary options to reduce antimicrobial use?’, J. Ethnopharmacol, 246, p. 112184. doi: 10.1016/j.jep.2019.112184.   
Zabela, V., Sampath, C., Oufir, M., Butterweck, V. and Hamburger, M. (2020) ‘Single dose pharmacokinetics of intravenous 3,4-dihydroxyphenylacetic acid and 3-hydroxyphenylacetic acid in rats’, Fitoterapia, 142, p. 104526. doi: 10.1016/j.fitote.2020.104526.   
Greenland, M., Knuiman, M. W., Hung, J., Nedkoff, L., Arnet, I., Rankin, J. M., Kilkenny, M. F. and Sanfilippo, F. M. (2020) ‘Cardioprotective medication adherence in Western Australians in the first year after myocardial infarction: restricted cubic spline analysis of adherence-outcome relationships’, Scientific Reports. Nature Publishing Group, 10(1), p. 4315. doi: 10.1038/s41598-020-60799-5.   
Du Preez, C. I., Gründemann, C., Mumbengegwi, D. R. and Huber, R. (2020) ‘Immunomodulatory effects of some Namibian plants traditionally used for treating inflammatory diseases’, Journal of ethnopharmacology, p. 112683. doi: 10.1016/j.jep.2020.112683.   
Vollrath, I., Mathaes, R., Sediq, A. S., Jere, D., Jörg, S., Huwyler, J. and Mahler, H.-C. (2020) ‘Subvisible Particulate Contamination in Cell Therapy Products-Can We Distinguish?’, Journal of pharmaceutical sciences, 109(1), pp. 216-219. doi: 10.1016/j.xphs.2019.09.002.   

2019

Lederer, A.-K., Hannibal, L., Hettich, M., Behringer, S., Spiekerkoetter, U., Steinborn, C., Gründemann, C., Zimmermann-Klemd, A. M., Müller, A., Simmet, T., Schmiech, M., Maul-Pavicic, A., Samstag, Y. and Huber, R. (2019) ‘Vitamin B12 Status Upon Short-Term Intervention with a Vegan Diet-A Randomized Controlled Trial in Healthy Participants’, Nutrients, 11(11), p. 2815. doi: 10.3390/nu11112815.   edoc
Zimmermann-Klemd, A. M., Konradi, V., Steinborn, C., Ücker, A., Falanga, C. M., Woelfle, U., Huber, R., Jürgenliemk, G., Rajbhandari, M. and Gründemann, C. (2019) ‘Influence of traditionally used Nepalese plants on wound healing and immunological properties using primary human cells in vitro’, Journal of ethnopharmacology, 235, pp. 415-423. doi: 10.1016/j.jep.2019.02.034.   edoc
Meyer zu Schwabedissen, H. and Hersberger, K. E. (2019) ‘Pharmakogenetik: Einfluss der Gene auf Medikamente’, in Personalisierte Medizin. Grundlagen für die interprofessionelle Aus-, Weiter- und Fortbildung von Gesundheitsfachleuten. Bern: Schweizerische Akademie der Medizinischen Wissenschaften (Swiss academic communications), pp. 70-76. doi: 10.5281/zenodo.3265194.   edoc
Venkataramani, V., Tanev, D. I., Strahle, C., Studier-Fischer, A., Fankhauser, L., Kessler, T., Körber, C., Kardorff, M., Ratliff, M., Xie, R., Horstmann, H., Messer, M., Paik, S. P., Knabbe, J., Sahm, F., Kurz, F. T., Acikgöz, A. A., Herrmannsdörfer, F., Agarwal, A., Bergles, D. E., Chalmers, A., Miletic, H., Turcan, S., Mawrin, C., Hänggi, D., Liu, H.-K., Wick, W., Winkler, F. and Kuner, T. (2019) ‘Glutamatergic synaptic input to glioma cells drives brain tumour progression’, Nature. Macmillan, 573(7775), pp. 532-538. doi: 10.1038/s41586-019-1564-x.   edoc
Brühwiler, L. D., Beeler, P. E., Böni, F., Giger, R., Wiedemeier, P. G., Hersberger, K. E. and Lutters, M. (2019) ‘A RCT evaluating a pragmatic in-hospital service to increase the quality of discharge prescriptions’, International Journal for Quality in Health Care. Oxford University Press, p. mzz043. doi: 10.1093/intqhc/mzz043.   edoc
da Costa, F. A., Mala-Ladova, K., Lee, V., Tous, S., Papastergiou, J., Griffiths, D., Chaumais, M.-C., Hersberger, K. E., Viola, R., Paulino, E., Lobban, T., Neubeck, L., Freedman, B. and Antoniou, S. (2019) ‘Awareness campaigns of atrial fibrillation as an opportunity for early detection by pharmacists: an international cross-sectional study’, Journal of thrombosis and thrombolysis. Springer, pp. 1-12. doi: 10.1007/s11239-019-02000-x.   edoc
Thompson, G. R., Beck, K. R., Patt, M., Kratschmar, D. V. and Odermatt, A. (2019) ‘Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2’, Journal of the Endocrine Society. Endocrine Society, 3(7), pp. 1361-1366. doi: 10.1210/js.2019-00189.   edoc | Open Access
Canonica, J., Frateschi, S., Boscardin, E., Ebering, A., Sergi, C., Jäger, Y., Peyrollaz, T., Mérillat, A.-M., Maillard, M., Klusonova, P., Odermatt, A., Koesters, R., Debonneville, A., Staub, O., Verouti, S. N. and Hummler, E. (2019) ‘Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl- Cotransporter NCC and Transiently Affects Sodium Handling’, Frontiers in physiology. Frontiers Media, 10, p. 989. doi: 10.3389/fphys.2019.00989.   edoc | Open Access
Keppner, A., Maric, D., Sergi, C., Ansermet, C., De Bellis, D., Kratschmar, D. V., Canonica, J., Klusonova, P., Fenton, R. A., Odermatt, A., Crambert, G., Hoogewijs, D. and Hummler, E. (2019) ‘Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion’, Scientific Reports. Nature Research, 9(1), p. 19540. doi: 10.1038/s41598-019-55995-x.   edoc | Open Access
Egli, J., Schlothauer, T., Spick, C., Seeber, S., Singer, T., Odermatt, A. and Iglesias, A. (2019) ‘The Binding of Human IgG to Minipig FcγRs - Implications for Preclinical Assessment of Therapeutic Antibodies’, Pharmaceutical research. Springer, 36(3), p. 47. doi: 10.1007/s11095-019-2574-y.   edoc | Open Access
Beck, K. R., Inderbinen, S. G., Kanagaratnam, S., Kratschmar, D. V., Jetten, A. M., Yamaguchi, H. and Odermatt, A. (2019) ‘11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ’, Journal of Lipid Research. American Society for Biochemistry and Molecular Biology, 60, pp. 1535-1546. doi: 10.1194/jlr.M092908.   edoc | Open Access
Vizeli, P., Meyer Zu Schwabedissen, H. E. and Liechti, M. E. (2019) ‘Role of serotonin transporter and receptor gene variations in the acute effects of MDMA in healthy subjects’, ACS chemical neuroscience. American Chemical Society, 10(7), pp. 3120-3131. doi: 10.1021/acschemneuro.8b00590.   edoc | Open Access
Pouw, R. B., Brouwer, M. C., de Gast, M., van Beek, A. E., van den Heuvel, L. P., Schmidt, C. Q., van der Ende, A., Sánchez-Corral, P., Kuijpers, T. W. and Wouters, D. (2019) ‘Potentiation of complement regulator factor H protects human endothelial cells from complement attack in aHUS sera’, Blood advances. American Society of Hematology, 3(4), pp. 621-632. doi: 10.1182/bloodadvances.2018025692.   edoc | Open Access
Strajhar, P., Vizeli, P., Patt, M., Dolder, P. C., Kratschmar, D. V., Liechti, M. E. and Odermatt, A. (2019) ‘Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study’, Journal of Steroid Biochemistry and Molecular Biology. Elsevier, 186, pp. 212-225. doi: 10.1016/j.jsbmb.2018.10.016.   edoc | Open Access
Mayer, F. P., Cintulova, D., Pittrich, D. A., Wimmer, L., Luethi, D., Holy, M., Jaentsch, K., Tischberger, S., Gmeiner, G., Hoener, M. C., Liechti, M. E., Mihovilovic, M. D. and Sitte, H. H. (2019) ‘Stereochemistry of phase-1 metabolites of mephedrone determines their effectiveness as releasers at the serotonin transporter’, Neuropharmacology. Elsevier, 148, pp. 199-209. doi: 10.1016/j.neuropharm.2018.12.032.   edoc | Open Access
Müller, F., Brändle, R., Liechti, M. E. and Borgwardt, S. (2019) ‘Neuroimaging of chronic MDMA (“ecstasy”) effects: A meta-analysis’, Neuroscience and biobehavioral reviews. Elsevier, 96, pp. 10-20. doi: 10.1016/j.neubiorev.2018.11.004.   edoc | Open Access
Wood, D. M., De La Rue, L., Hosin, A. A., Jurgens, G., Liakoni, E., Heyerdahl, F., Hovda, K. E., Dines, A., Giraudon, I., Liechti, M. E. and Dargan, P. I. (2019) ‘Poor Identification of Emergency Department Acute Recreational Drug Toxicity Presentations Using Routine Hospital Coding Systems: the Experience in Denmark, Switzerland and the UK’, Journal of medical toxicology. Springer, pp. 1-9. doi: 10.1007/s13181-018-0687-z.   edoc | Open Access
Maes, K. A., Ruppanner, J. A., Imfeld-Isenegger, T. L., Hersberger, K. E., Lampert, M. L. and Boeni, F. (2019) ‘Dispensing of Prescribed Medicines in Swiss Community Pharmacies-Observed Counselling Activities’, Pharmacy. MDPI, 7(1), pp. 1-16. doi: 10.3390/pharmacy7010001.   edoc | Open Access
Ricklin, D., Mastellos, D. C. and Lambris, J. D. (2019) ‘Therapeutic targeting of the complement system’, Nature reviews. Drug discovery, pp. DOI:10.1038/41573-019. doi: 10.1038/s41573-019-0055-y.   
van Griensven, M., Ricklin, D., Denk, S., Halbgebauer, R., Braun, C. K., Schultze, A., Hönes, F., Koutsogiannaki, S., Primikyri, A., Reis, E., Messerer, D., Hafner, S., Radermacher, P., Biglarnia, A.-R., Resuello, R. R. G., Tuplano, J. V., Mayer, B., Nilsson, K., Nilsson, B., Lambris, J. D. and Huber-Lang, M. (2019) ‘Protective Effects of the Complement Inhibitor Compstatin CP40 in Hemorrhagic Shock’, Shock (Augusta, Ga.), 51(1), pp. 78-87. doi: 10.1097/SHK.0000000000001127.   
Arnet, I., Rothen, J.-P. and Hersberger, K. E. (2019) ‘Validation of a Novel Electronic Device for Medication Adherence Monitoring of Ambulatory Patients’, Pharmacy (Basel, Switzerland), 7(4), p. nn. doi: 10.3390/pharmacy7040155.   
Burkard, T., Moser, M., Rauch, M., Jick, S. S. and Meier, C. R. (2019) ‘Utilization pattern of hormone therapy in UK general practice between 1996 and 2015: a descriptive study’, Menopause (New York, N.Y.), 26(7), pp. 741-749. doi: 10.1097/GME.0000000000001300.   
Suenderhauf, C., Berger, B., Puchkov, M., Schmid, Y., Müller, S., Huwyler, J., Haschke, M., Krähenbühl, S. and Duthaler, U. (2019) ‘Pharmacokinetics and phenotyping properties of the “Basel” phenotyping cocktail combination capsule in healthy male adults’, British journal of clinical pharmacology, pp. 1-10. doi: 10.1111/bcp.14157.   
Trinh, B., Hepprich, M., Betz, M. J., Burkard, T., Cavelti-Weder, C., Seelig, E., Meienberg, F., Kratschmar, D. V., Beuschlein, F., Reincke, M., Odermatt, A., Hall, M. N., Donath, M. Y. and Swierczynska, M. M. (2019) ‘Treatment of Primary Aldosteronism with mTORC1 Inhibitors’, The Journal of clinical endocrinology and metabolism, pp. 4703-4714. doi: 10.1210/jc.2019-00563.   
Hamburger, M. (2019) ‘HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products - principles and recent examples.’, Pharm. Biol, 57, pp. 328-334. doi: 10.1080/13880209.2019.1606261.   
Ferreira, C., Meyer, R. and Meyer Zu Schwabedissen, H. E. (2019) ‘The nuclear receptors PXR and LXR are regulators of the scaffold protein PDZK1’, Biochimica et biophysica acta. Gene regulatory mechanisms, 1862(4), pp. 447-456. doi: 10.1016/j.bbagrm.2019.02.007.   
Rothen, J.-P., Hersberger, K. E. and Arnet, I. (2019) ‘Comment on “Efficacy of long-term oral vitamin B12 supplementation after total gastrectomy: results from a prospective study”’, GE Portuguese Journal of Gastroenterology, 26(3), pp. 226-227. doi: 10.1159/000495768.   
Ehrsam, D., Porta, F., Hussner, J., Seibert, I. and Meyer Zu Schwabedissen, H. E. (2019) ‘PDMS-PMOXA-Nanoparticles Featuring a Cathepsin B-Triggered Release Mechanism’, Materials (Basel, Switzerland), 12(17), p. 18. doi: 10.3390/ma12172836.   
Vavanikunnel, J., Charlier, S., Becker, C., Schneider, C., Jick, S. S., Meier, C. R. and Meier, C. (2019) ‘Association Between Glycemic Control and Risk of Fracture in Diabetic Patients: A Nested Case-Control Study’, The Journal of clinical endocrinology and metabolism, 104(5), pp. 1645-1654. doi: 10.1210/jc.2018-01879.   
Malagnino, V., Duthaler, U., Seibert, I., Krähenbühl, S. and Meyer Zu Schwabedissen, H. E. (2019) ‘OATP1B3-1B7 (LST-3TM12) Is a Drug Transporter That Affects Endoplasmic Reticulum Access and the Metabolism of Ezetimibe’, Molecular pharmacology, 96(2), pp. 128-137. doi: 10.1124/mol.118.114934.   
Schneider, R., Reinau, D., Schur, N., Blozik, E., Früh, M., Signorell, A., Meier, C. R. and Schwenkglenks, M. (2019) ‘Drug prescription patterns, polypharmacy and potentially inappropriate medication in Swiss nursing homes: a descriptive analysis based on claims data’, Swiss medical weekly, 149, p. w20126. doi: 10.4414/smw.2019.20126.   
Mueller, A. M., Meier, C. R., Jick, S. S. and Schneider, C. (2019) ‘Weight change and blood glucose concentration as markers for pancreatic cancer in subjects with new-onset diabetes mellitus: A matched case-control study’, Pancreatology : official journal of the International Association of Pancreatology (IAP) . [et al.], 19(4), pp. 578-586. doi: 10.1016/j.pan.2019.03.006.   
Rudin, D., Spoendlin, J., Cismaru, A. L., Liakoni, E., Bonadies, N., Amstutz, U., Meier, C. R., Krähenbühl, S. and Haschke, M. (2019) ‘Metamizole-associated neutropenia: Comparison of patients with neutropenia and metamizole-tolerant patients’, European journal of internal medicine, 68, pp. 36-43. doi: 10.1016/j.ejim.2019.07.029.   
Oufir, M., Zabela, V., Hettich, T., Schlotterbeck, G., Wimmer, L., Mihovilovic, M. D., Guillet, F., Bouaita, B., Shevchenko, B. and Hamburger, M. (2019) ‘Piperine analogs as modulators of the central nervous system.’, Chimia, 73, p. 206. doi: 10.2533/chimia.2019.1.   
Seliger, C., Luber, C., Gerken, M., Schaertl, J., Proescholdt, M., Riemenschneider, M. J., Meier, C. R., Bogdahn, U., Leitzmann, M. F., Klinkhammer-Schalke, M. and Hau, P. (2019) ‘Use of metformin and survival of patients with high-grade glioma’, International journal of cancer, 144(2), pp. 273-280. doi: 10.1002/ijc.31783.   
Tsachaki, M. and Odermatt, A. (2019) ‘Subcellular localization and membrane topology of 17β-hydroxysteroid dehydrogenases’, Molecular and cellular endocrinology, 489, pp. 98-106. doi: 10.1016/j.mce.2018.07.003.   
Damen, N. L., Van den Bemt, B. J. F., Hersberger, K. E., Papastergiou, J., Alves da Costa, F., Rydant, S., Wartenberg, N. S., Lobban, T., Arnet, I., Antoniou, S. and International Pharmacists for Anticoagulation Care Taskforce (2019) ‘Creating an interprofessional guideline to support patients receiving oral anticoagulation therapy: a Delphi exercise’, International Journal of Clinical Pharmacy, 41(4), pp. 1012-1020. doi: 10.1007/s11096-019-00844-0.   
Santos, S., Haslinger, C., Mennet, M., von Mandach, U., Hamburger, M. and Simões-Wüst, A. P. (2019) ‘Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study’, BMC Complem. Altern. Med, 19, p. 292. doi: 10.1186/s12906-019-2711-5.   
Malagnino, V., Hussner, J., Issa, A., Midzic, A. and Meyer zu Schwabedissen, H. E. (2019) ‘OATP1B3-1B7 a novel Organic Anion Transporting Polypeptide is modulated by FXR ligands and transports bile acids’, American journal of physiology. Gastrointestinal and liver physiology, 316(6), pp. G751-G762. doi: 10.1152/ajpgi.00330.2018.   
Roel-Touris, J., Don, C. G., Vargas Honorato, R., Rodrigues, J. P. G. L. M. and Bonvin, A. M. J. J. (2019) ‘Less is more: Coarse-grained integrative modeling of large biomolecular assemblies with HADDOCK’, Journal of chemical theory and computation, p. 9b00310. doi: 10.1021/acs.jctc.9b00310.   

2018

Rabbani, S., Fiege, B., Eris, D., Silbermann, M., Jakob, R. P., Navarra, G., Maier, T. and Ernst, B. (2018) ‘Conformational Switch of the Bacterial Adhesin FimH in the Absence of the Regulatory Domain: Engineering a Minimalistic Allosteric System’, Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 293(5), pp. 1835-1849. doi: 10.1074/jbc.M117.802942.   edoc
Ditter, D., Nieto, A., Mahler, H.-C., Roehl, H., Wahl, M., Huwyler, J. and Allmendinger, A. (2018) ‘Evaluation of Glass Delamination Risk in Pharmaceutical 10 mL/10R Vials’, Journal of Pharmaceutical Sciences, 107(2), pp. 624-637. doi: 10.1016/j.xphs.2017.09.016.   edoc
Schäfer, A. M., Bock, T. and Meyer Zu Schwabedissen, H. E. (2018) ‘Establishment and Validation of Competitive Counterflow as a Method To Detect Substrates of the Organic Anion Transporting Polypeptide 2B1’, Molecular pharmaceutics, 15(12), pp. 5501-5513. doi: 10.1021/acs.molpharmaceut.8b00631.   edoc
Duthaler, U., Suenderhauf, C., Karlsson, M. O., Hussner, J., Meyer Zu Schwabedissen, H., Krähenbühl, S. and Hammann, F. (2018) ‘Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers’, British journal of clinical pharmacology, 85(3), pp. 626-633. doi: 10.1111/bcp.13840.   edoc
Mühlebach, S. (2018) ‘Regulatory challenges of nanomedicines and their follow-on versions: A generic or similar approach?’, Advanced drug delivery reviews, 131, pp. 122-131. doi: 10.1016/j.addr.2018.06.024.   edoc
Sosnik, A. and Mühlebach, S. (2018) ‘Editorial: Drug Nanoparticles and Nano-Cocrystals: From Production and Characterization to Clinical Translation’, Advanced drug delivery reviews, 131, pp. 1-2. doi: 10.1016/j.addr.2018.09.001.   edoc
Knoeff, J., Flühmann, B. and Mühlebach, S. (2018) ‘Medication practice in hospitals: are nanosimilars evaluated and substituted correctly?’, European journal of hospital pharmacy : science and practice, 25(2), pp. 79-84. doi: 10.1136/ejhpharm-2016-001059.   edoc
Hösli, R., König, S. and Mühlebach, S. F. (2018) ‘Development and Validation of an LC-MS/MS Method and Comparison with a GC-MS Method to Measure Phenytoin in Human Brain Dialysate, Blood, and Saliva’, Journal of analytical methods in chemistry, 2018, p. 8274131. doi: 10.1155/2018/8274131.   edoc
Aubry, E., Aeberhard, C., Bally, L., Nuoffer, J.-M., Risch, L., Mühlebach, S., Burgunder, J.-M. and Stanga, Z. (2018) ‘Are patients affected by mitochondrial disorders at nutritional risk?’, Nutrition J (Burbank, Los Angeles County, Calif.), 47, pp. 56-62. doi: 10.1016/j.nut.2017.09.011.   edoc
Gruntz, K., Bloechliger, M., Becker, C., Jick, S., Fuhr, P., Meier, C. R. and Rüegg, S. (2018) ‘Reply to “Intriguing association of Parkinson disease and epileptic seizures”’, Annals of neurology, 84(1), pp. 162-163. doi: 10.1002/ana.25252.   edoc
Bloechliger, M., Reinau, D., Spoendlin, J., Chang, S.-C., Kuhlbusch, K., Heaney, L. G., Jick, S. S. and Meier, C. R. (2018) ‘Adverse events profile of oral corticosteroids among asthma patients in the UK: cohort study with a nested case-control analysis’, Respiratory research, 19(1), p. 75. doi: 10.1186/s12931-018-0742-y.   edoc
Reinau, D., Schwenkglenks, M., Früh, M., Signorell, A., Blozik, E. and Meier, C. R. (2018) ‘Glucocorticoids and the Risk of Peptic Ulcer Bleeding: Case-Control Analysis Based on Swiss Claims Data’, Drug safety, 41(7), pp. 725-730. doi: 10.1007/s40264-018-0645-3.   edoc
Polymeris, A. A., Albert, V., Hersberger, K. E., Engelter, S. T., Schaedelin, S., Arnet, I. and Lyrer, P. A. (2018) ‘Protocol for MAAESTRO: Electronic Monitoring and Improvement of Adherence to Direct Oral Anticoagulant Treatment-A Randomized Crossover Study of an Educational and Reminder-Based Intervention in Ischemic Stroke Patients Under Polypharmacy’, Frontiers in Neurology, 9, p. 1134. doi: 10.3389/fneur.2018.01134.   edoc
Grunewald, F., Steinborn, C., Huber, R., Wille, R., Meier, S., Alresly, Z., Lindequist, U. and Gründemann, C. (2018) ‘Effects of Birch Polypore Mushroom, Piptoporus betulinus (Agaricomycetes), the “Iceman’s Fungus”, on Human Immune Cells’, International journal of medicinal mushrooms, 20(12), pp. 1135-1147. doi: 10.1615/IntJMedMushrooms.2018029154.   edoc
von Schönfeld, C., Huber, R., Trittler, R., Kammerer, B., Garcia-Käufer, M. and Gründemann, C. (2018) ‘Rosemary has immunosuppressant activity mediated through the STAT3 pathway’, Complementary therapies in medicine, 40, pp. 165-170. doi: 10.1016/j.ctim.2018.03.004.   edoc
Stadlbauer, S., Steinborn, C., Klemd, A., Hattori, F., Ohmori, K., Suzuki, K., Huber, R., Wolf, P. and Gründemann, C. (2018) ‘Impact of Green Tea Catechin ECG and Its Synthesized Fluorinated Analogue on Prostate Cancer Cells and Stimulated Immunocompetent Cells’, Planta medica, 84(11), pp. 813-819. doi: 10.1055/s-0044-102099.   edoc
Rentsch, G., Steinborn, C., Klemd, A. M., Kienle, G. S., Gründemann, C. and Huber, R. (2018) ‘Investigations on the constitutional types under consideration of anthropometric data, autonomic regulation and immunological parameters’, Complementary therapies in medicine, 40, pp. 133-144. doi: 10.1016/j.ctim.2018.04.011.   edoc
Gründemann, C. and Huber, R. (2018) ‘Chemoprevention with isothiocyanates - From bench to bedside’, Cancer letters, 414, pp. 26-33. doi: 10.1016/j.canlet.2017.10.033.   edoc
Steinborn, C., Potterat, O., Meyer, U., Trittler, R., Stadlbauer, S., Huber, R. and Gründemann, C. (2018) ‘In Vitro Anti-inflammatory Effects of Equisetum Arvense Are Not Solely Mediated by Silica’, Planta medica, 84(8), pp. 519-526. doi: 10.1055/s-0043-123075.   edoc
Venkataramani, V., Kardorff, M., Herrmannsdörfer, F., Wieneke, R., Klein, A., Tampé, R., Heilemann, M. and Kuner, T. (2018) ‘Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins’, Scientific Reports. Nature Publishing Group, 8(1), p. 5507. doi: 10.1038/s41598-018-23818-0.   edoc
Appenzeller-Herzog, C. and Riemer, J. (2018) ‘Techniques to Monitor Disulfide Bond Formation and the Reduction Potential of Cysteine-Cystine Couples In vitro and In vivo’, in Matthias J. Feige (ed.) Oxidative Folding of Proteins: Basic Principles, Cellular Regulation and Engineering. Cambridge UK: The Royal Society of Chemistry (Chemical biology), pp. 34-51. doi: 10.1039/9781788013253-00034.   edoc
Pouw, R. B., Brouwer, M. C., van Beek, A. E., Józsi, M., Wouters, D. and Kuijpers, T. W. (2018) ‘Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4’, Frontiers in Immunology. Frontiers Media, 9, p. 729. doi: 10.3389/fimmu.2018.00729.   edoc | Open Access
Pouw, R. B., Gómez Delgado, I., López Lera, A., Rodríguez de Córdoba, S., Wouters, D., Kuijpers, T. W. and Sánchez-Corral, P. (2018) ‘High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B’, Frontiers in Immunology. Frontiers Media, 9, p. 848. doi: 10.3389/fimmu.2018.00848.   edoc | Open Access
Maes, K. A., Hersberger, K. E. and Lampert, M. L. (2018) ‘Pharmaceutical interventions on prescribed medicines in community pharmacies: focus on patient-reported problems’, International journal of clinical pharmacy. Springer, 40(2), pp. 335-340. doi: 10.1007/s11096-018-0595-y.   edoc
Harris, C. L., Pouw, R. B., Kavanagh, D., Sun, R. and Ricklin, D. (2018) ‘Developments in anti-complement therapy; from disease to clinical trial’, Molecular immunology. Elsevier, 102, pp. 89-119. doi: 10.1016/j.molimm.2018.06.008.   edoc
Dolder, P. C., Strajhar, P., Vizeli, P., Odermatt, A. and Liechti, M. E. (2018) ‘Acute effects of lisdexamfetamine and D-amphetamine on social cognition and cognitive performance in a placebo-controlled study in healthy subjects’, Psychopharmacology. Springer, 235(5), pp. 1389-1402. doi: 10.1007/s00213-018-4849-0.   edoc
Simmler, L. D. and Liechti, M. E. (2018) ‘Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances’, Handbook of experimental pharmacology. Springer, pp. 143-164. doi: 10.1007/164_2018_113.   edoc | Open Access
Boxler, M. I., Streun, G. L., Liechti, M. E., Schmid, Y., Kraemer, T. and Steuer, A. E. (2018) ‘Human Metabolome Changes after a Single Dose of 3,4-Methylenedioxymethamphetamine (MDMA) with Special Focus on Steroid Metabolism and Inflammation Processes’, Journal of proteome research. American Chemical Society, 17(8), pp. 2900-2907. doi: 10.1021/acs.jproteome.8b00438.   edoc | Open Access
Leuppi-Taegtmeyer, A., Duthaler, U., Hammann, F., Schmid, Y., Dickenmann, M., Amico, P., Jehle, A. W., Kalbermatter, S., Lenherr, C., Meyer Zu Schwabedissen, H. E., Haschke, M., Liechti, M. E. and Krähenbühl, S. (2018) ‘Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions’, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. Oxford University Press, 34(4), pp. 692-702. doi: 10.1093/ndt/gfy285.   edoc
Müller, F., Liechti, M. E., Lang, U. E. and Borgwardt, S. (2018) ‘Advances and challenges in neuroimaging studies on the effects of serotonergic hallucinogens: Contributions of the resting brain’, Progress in brain research. Elsevier, 242, pp. 159-177. doi: 10.1016/bs.pbr.2018.08.004.   edoc
da Costa, F. A. and Hersberger , K. E. (2018) ‘Paying for Pharmaceutical Care’, in Alvarez-Risco, A. (ed.) The Pharmacist Guide to Implementing Pharmaceutical Care. Cham: Springer International Publishing, pp. 461-472. doi: 10.1007/978-3-319-92576-9_3.   edoc
Griese-Mammern, N., Schulz, M., Böni, F. and Hersberger, K. E. (2018) ‘Medication Review and Medication Reconciliation’, in Alves da Costa, F., van Mil, J. W. F., and Alvarez-Risco, A. (eds) The Pharmacist Guide to Implementing Pharmaceutical Care. Cham: Springer International Publishing, pp. 69-88. doi: 10.1007/978-3-319-92576-9.   edoc
Zabela, V., Hettich, T., Schlotterbeck, G., Wimmer, L., Mihovilovic, M. D., Guillet, F., Bouaita, B., Shevchenko, B., Hamburger, M. and Oufir, M. (2018) ‘GABAA receptor activity modulating piperine analogs: In vitro metabolic stability, metabolite identification, CYP450 reaction phenotyping, and protein binding.’, Journal of Chromatography B, 1072, pp. 379-389. doi: 10.1016/j.jchromb.2017.11.036.   edoc
Dolder, P. C., Müller, F., Schmid, Y., Borgwardt, S. J. and Liechti, M. E. (2018) ‘Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects’, Psychopharmacology. Springer, 235(2), pp. 467-479. doi: 10.1007/s00213-017-4650-5.   edoc | Open Access
Schmid, Y. and Liechti, M. E. (2018) ‘Long-lasting subjective effects of LSD in normal subjects’, Psychopharmacology. Springer, 235(2), pp. 535-545. doi: 10.1007/s00213-017-4733-3.   edoc | Open Access
Vizeli, P., Meyer Zu Schwabedissen, H. E. and Liechti, M. E. (2018) ‘No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA’, European Journal of Clinical Pharmacology. Springer, 74(3), pp. 275-283. doi: 10.1007/s00228-017-2392-2.   edoc | Open Access
Rickli, A., Liakoni, E., Hoener, M. C. and Liechti, M. E. (2018) ‘Opioid-induced inhibition of the human 5-HT and noradrenaline transporters in vitro: link to clinical reports of serotonin syndrome’, British Journal of Pharmacology. Wiley, 175(3), pp. 532-543. doi: 10.1111/bph.14105.   edoc | Open Access
Liakoni, E., Yates, C., Dines, A. M., Dargan, P. I., Heyerdahl, F., Hovda, K. E., Wood, D. M., Eyer, F., Liechti, M. E. and Euro-DEN Plus Research Group (2018) ‘Acute recreational drug toxicity: Comparison of self-reports and results of immunoassay and additional analytical methods in a multicenter European case series’, Medicine. Lippincott, Williams & Wilkins, 97(5), p. e9784. doi: 10.1097/MD.0000000000009784.   edoc | Open Access
Luethi, D. and Liechti, M. E. (2018) ‘Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics’, International Journal of Neuropsychopharmacology. Oxford University Press, 21(10), pp. 926-931. doi: 10.1093/ijnp/pyy047.   edoc | Open Access
Maier, J., Mayer, F. P., Luethi, D., Holy, M., Jäntsch, K., Reither, H., Hirtler, L., Hoener, M. C., Liechti, M. E., Pifl, C., Brandt, S. D. and Sitte, H. H. (2018) ‘The psychostimulant (±)-cis-4,4’-dimethylaminorex (4,4’-DMAR) interacts with human plasmalemmal and vesicular monoamine transporters’, Neuropharmacology. Elsevier, 138, pp. 282-291. doi: 10.1016/j.neuropharm.2018.06.018.   edoc | Open Access

2017

Widmer, N., Schumacher, L., Meister, T., Krähenbühl, J.-M., Mühlebach, S. and Bonnabry, P. (2017) ‘Notfall- und Katastrophenpharmazie: Neues Schweizer Fachzentrum’, PharmaJournal. Schweizer Apothekerzeitung. PharmaSuisse, 155(15), pp. 14-17.   edoc | Open Access
Brecht, K., Riebel, V., Couttet, P., Paech, F., Wolf, A., Chibout, S.-D., Pognan, F., Krähenbühl, S. and Uteng, M. (2017) ‘Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin’, Toxicology in Vitro, 40, pp. 55-65. doi: 10.1016/j.tiv.2016.12.001.   edoc
Aeberhard , C. and Mühlebach, S. (2017) ‘Parenterale Ernährung - Grundlagen und Durchführung (Parenteral nutrition - basics and good practice)’, Aktuelle Ernährungsmedizin, 42(1), pp. 53-76. doi: 10.1055/s-0042-121786.   edoc
Astier, A., Barton Pai, A., Bissig, M., Crommelin, D. J. A., Flühmann, B., Hecq, J.-D., Knoeff, J., Lipp, H.-P., Morell-Baladrón, A. and Mühlebach, S. (2017) ‘How to select a nanosimilar’, Annals of the New York Academy of Sciences, 1407(1), pp. 50-62. doi: 10.1111/nyas.13382.   edoc
Hussaarts, L., Mühlebach, S., Shah, V. P., McNeil, S., Borchard, G., Flühmann, B., Weinstein, V., Neervannan, S., Griffiths, E., Jiang, W., Wolff-Holz, E., Crommelin, D. J. A. and de Vlieger, J. S. B. (2017) ‘Equivalence of complex drug products: advances in and challenges for current regulatory frameworks’, Annals of the New York Academy of Sciences, 1407(1), pp. 39-49. doi: 10.1111/nyas.13347.   edoc
Aeberhard, C., Steuer, C., Saxer, C., Huber, A., Stanga, Z. and Mühlebach, S. (2017) ‘Physicochemical stability and compatibility testing of levetiracetam in all-in-one parenteral nutrition admixtures in daily practice’, European journal of pharmaceutical sciences, 96, pp. 449-455. doi: 10.1016/j.ejps.2016.10.015.   edoc
Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Fearon, K., Hütterer, E., Isenring, E., Kaasa, S., Krznaric, Z., Laird, B., Larsson, M., Laviano, A., Mühlebach, S., Muscaritoli, M., Oldervoll, L., Ravasco, P., Solheim, T., Strasser, F., de van der Schueren, M. and Preiser, J.-C. (2017) ‘ESPEN guidelines on nutrition in cancer patients’, Clinical nutrition, 36(1), pp. 11-48. doi: 10.1016/j.clnu.2016.07.015.   edoc
Engeli, R. T., Tsachaki, M., Hassan, H. A., Sager, C. P., Essawi, M. L., Gad, Y. Z., Kamel, A. K., Mazen, I. and Odermatt, A. (2017) ‘Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients’, The journal of sexual medicine, 14(9), pp. 1165-1174. doi: 10.1016/j.jsxm.2017.07.006.   edoc
Knöpfel, T., Pastor-Arroyo, E. M., Schnitzbauer, U., Kratschmar, D. V., Odermatt, A., Pellegrini, G., Hernando, N. and Wagner, C. A. (2017) ‘The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction’, Scientific reports, 7(1), p. 11018. doi: 10.1038/s41598-017-10390-2.   edoc
Dolder, P. C., Strajhar, P., Vizeli, P., Hammann, F., Odermatt, A. and Liechti, M. E. (2017) ‘Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects’, Frontiers in pharmacology, 8, p. 617. doi: 10.3389/fphar.2017.00617.   edoc
van Beek, A. E., Pouw, R. B., Brouwer, M. C., van Mierlo, G., Geissler, J., Ooijevaar-de Heer, P., de Boer, M., van Leeuwen, K., Rispens, T., Wouters, D. and Kuijpers, T. W. (2017) ‘Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma’, Frontiers in Immunology. Frontiers Media, 8, p. 1328. doi: 10.3389/fimmu.2017.01328.   edoc
Engeli, R. T., Rohrer, S. R., Vuorinen, A., Herdlinger, S., Kaserer, T., Leugger, S., Schuster, D. and Odermatt, A. (2017) ‘Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases’, International Journal of Molecular Sciences, 18(9), pp. 1-13. doi: 10.3390/ijms18092007.   edoc | Open Access
Aghagolzadeh, P., Radpour, R., Bachtler, M., van Goor, H., Smith, E. R., Lister, A., Odermatt, A., Feelisch, M. and Pasch, A. (2017) ‘Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation’, Atherosclerosis, 265, pp. 78-86. doi: 10.1016/j.atherosclerosis.2017.08.012.   edoc
Morgan, R. A., Beck, K. R., Nixon, M., Homer, N. Z. M., Crawford, A. A., Melchers, D., Houtman, R., Meijer, O. C., Stomby, A., Anderson, A. J., Upreti, R., Stimson, R. H., Olsson, T., Michoel, T., Cohain, A., Ruusalepp, A., Schadt, E. E., Björkegren, J. L. M., Andrew, R., Kenyon, C. J., Hadoke, P. W. F., Odermatt, A., Keen, J. A. and Walker, B. R. (2017) ‘Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity’, Scientific Reports, 7(1), p. 10633. doi: 10.1038/s41598-017-10410-1.   edoc | Open Access
Alesutan, I., Voelkl, J., Feger, M., Kratschmar, D. V., Castor, T., Mia, S., Sacherer, M., Viereck, R., Borst, O., Leibrock, C., Gawaz, M., Kuro-O, M., Pilz, S., Tomaschitz, A., Odermatt, A., Pieske, B., Wagner, C. A. and Lang, F. (2017) ‘Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells’, Scientific Reports, 7(1), p. 2059. doi: 10.1038/s41598-017-01882-2.   edoc | Open Access
Monzel, J. V., Budde, T., Meyer zu Schwabedissen, H. E., Schwebe, M., Bien-Möller, S., Lütjohann, D., Kroemer, H. K., Jedlitschky, G. and Grube, M. (2017) ‘Doxorubicin enhance oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters’, Biochemical pharmacology, 144, pp. 108-119. doi: 10.1016/j.bcp.2017.08.008.   edoc
Flesch, D., Cheung, S.-Y., Schmidt, J., Gabler, M., Heitel, P., Kramer, J., Kaiser, A., Hartmann, M., Lindner, M., Lüddens-Dämgen, K., Heering, J., Lamers, C., Lüddens, H., Wurglics, M., Proschak, E., Schubert-Zsilavecz, M. and Merk, D. (2017) ‘Nonacidic Farnesoid X Receptor Modulators’, Journal of Medicinal Chemistry, 60(16), pp. 7199-7205. doi: 10.1021/acs.jmedchem.7b00903.   edoc
Cramer, J. and Klebe, G. (2017) ‘An Allyl Protection and Improved Purification Strategy Enables the Synthesis of Functionalized Phosphonamidate Peptides’, Synthesis. GEORG THIEME VERLAG KG, 49(8), pp. 1857-1866. doi: 10.1055/s-0036-1588393.   edoc
Cramer, J., Krimmer, S. G., Fridh, V., Wulsdorf, T., Karlsson, R., Heine, A. and Klebe, G. (2017) ‘Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin’, ACS Chemical Biology, 12(1), pp. 225-233. doi: 10.1021/acschembio.6b00979.   edoc
Cramer, J., Schiebel, J., Wulsdorf, T., Grohe, K., Najbauer, E. E., Ehrmann, F. R., Radeva, N., Zitzer, N., Linne, U., Linser, R., Heine, A. and Klebe, G. (2017) ‘A False-Positive Screening Hit in Fragment-Based Lead Discovery: Watch out for the Red Herring’, Angewandte Chemie (International Edition), 56(7), pp. 1908-1913. doi: 10.1002/anie.201609824.   edoc
Cramer, J., Krimmer, S. G., Heine, A. and Klebe, G. (2017) ‘Paying the Price of Desolvation in Solvent-Exposed Protein Pockets: Impact of Distal Solubilizing Groups on Affinity and Binding Thermodynamics in a Series of Thermolysin Inhibitors’, Journal of Medicinal Chemistry, 60(13), pp. 5791-5799. doi: 10.1021/acs.jmedchem.7b00490.   edoc
Krimmer, S. G., Cramer, J., Schiebel, J., Heine, A. and Klebe, G. (2017) ‘How Nothing Boosts Affinity: Hydrophobic Ligand Binding to the Virtually Vacated S1′ Pocket of Thermolysin’, Journal of the American Chemical Society, 139(30), pp. 10419-10431. doi: 10.1021/jacs.7b05028.   edoc
Zhang, P., Hevey, R. and Ling, C.-C. (2017) ‘Total Synthesis of β-d-ido-Heptopyranosides Related to Capsular Polysaccharides of Campylobacter jejuni HS:4’, The Journal of Organic Chemistry, 82(18), pp. 9662-9674. doi: 10.1021/acs.joc.7b01752.   edoc
Hevey, R. and Ling, C.-C. (2017) ‘Studies on the 6-homologation of β-D-idopyranosides’, Carbohydrate Research, 445, pp. 65-74. doi: 10.1016/j.carres.2017.04.007.   edoc
Prestin, K., Olbert, M., Hussner, J., Völzke, H. and Meyer zu Schwabedissen, H. E. (2017) ‘Functional assessment of genetic variants located in the promoter of SHP1 (NR0B2)’, Pharmacogenetics and Genomics, 27(11), pp. 410-415. doi: 10.1097/FPC.0000000000000310.   edoc
Legeza, B., Marcolongo, P., Gamberucci, A., Varga, V., Bánhegyi, G., Benedetti, A. and Odermatt, A. (2017) ‘Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome’, Nutrients, 9(5), p. E426. doi: 10.3390/nu9050426.   edoc | Open Access
Vuorinen, A., Engeli, R. T., Leugger, S., Bachmann, F., Akram, M., Atanasov, A. G., Waltenberger, B., Temml, V., Stuppner, H., Krenn, L., Ateba, S. B., Njamen, D., Davis, R. A., Odermatt, A. and Schuster, D. (2017) ‘Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2’, Journal of Natural Products, 80(4), pp. 965-974. doi: 10.1021/acs.jnatprod.6b00950.   edoc | Open Access
Vuorinen, A., Engeli, R. T., Leugger, S., Kreutz, C. R., Schuster, D., Odermatt, A. and Matuszczak, B. (2017) ‘Phenylbenzenesulfonates and -sulfonamides as 17β-hydroxysteroid dehydrogenase type 2 inhibitors: Synthesis and SAR-analysis’, Bioorganic & Medicinal Chemistry Letters, 27(13), pp. 2982-2985. doi: 10.1016/j.bmcl.2017.05.005.   edoc
Nolte, I., Munoz, M., Tragante, V., Amare, A., Jansen, R., Vaez, A., von der Heyde, B., Avery, C., Bis, J., Dierckx, B., van Dongen, J., Gogarten, S., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, S., Jaju, D., Kerr, K., Kluttig, A., Krijthe, B., Kumar, J., van der Laan, S., Lyytikäinen, L., Maihofer, A., Minassian, A., van der Most, P., Müller-Nurasyid, M., Nivard, M., Salvi, E., Stewart, J., Thayer, J., Verweij, N., Wong, A., Zabaneh, D., Zafarmand, M., Abdellaoui, A., Albarwani, S., Albert, C., Alonso, A., Ashar, F., Auvinen, J., Axelsson, T., Baker, D., de Bakker, P., Barcella, M., Bayoumi, R., Bieringa, R., Boomsma, D., Boucher, G., Britton, A., Christophersen, I., Dietrich, A., Ehret, G., Ellinor, P., Eskola, M., Felix, J., Floras, J., Franco, O., Friberg, P., Gademan, M. G. J., Geyer, M., Giedraitis, V., Hartman, C., Hemerich, D., Hofman, A., Hottenga, J., Huikuri, H., Hutri-Kähönen, N., Jouven, X., Junttila, J., Juonala, M., Kiviniemi, A., Kors, J., Kumari, M., Kuznetsova, T., Laurie, C., Lefrandt, J., Li, Y., Li, Y., Liao, D., Limacher, M., Lin, H., Lindgren, C., Lubitz, S., Mahajan, A., McKnight, B., Meyer zu Schwabedissen, H., Milaneschi, Y., Mononen, N., Morris, A., Nalls, M., Navis, G., Neijts, M., Nikus, K., North, K., O’Connor, D., Ormel, J., Perz, S., Peters, A., Psaty, B., Raitakari, O., Risbrough, V., Sinner, M., Siscovick, D., Smit, J., Smith, N., Soliman, E., Sotoodehnia, N., Staessen, J., Stein, P., Stilp, A., Stolarz-Skrzypek, K., Strauch, K., Sundström, J., Swenne, C., Syvänen, A., Tardif, J., Taylor, K., Teumer, A., Thornton, T., Tinker, L., Uitterlinden, A., van Setten, J., Voss, A., Waldenberger, M., Wilhelmsen, K., Willemsen, G., Wong, Q., Zhang, Z., Zonderman, A., Cusi, D., Evans, M., Greiser, H., van der Harst, P., Hassan, M., Ingelsson, E., Järvelin, M., Kääb, S., Kähönen, M., Kivimaki, M., Kooperberg, C., Kuh, D., Lehtimäki, T., Lind, L., Nievergelt, C., O’Donnell, C., Oldehinkel, A., Penninx, B., Reiner, A., Riese, H., van Roon, A., Rioux, J., Rotter, J., Sofer, T., Stricker, B., Tiemeier, H., Vrijkotte, T., Asselbergs, F., Brundel, B., Heckbert, S., Whitsel, E., den Hoed, M., Snieder, H. and de Geus, E. (2017) ‘Genetic loci associated with heart rate variability and their effects on cardiac disease risk’, Nature Communications, 8, p. 15805. doi: 10.1038/ncomms15805.   edoc | Open Access
Kim, M., Deacon, P., Tirona, R., Kim, R., Pin, C., Meyer zu Schwabedissen, H., Wang, R. and Schwarz, U. (2017) ‘Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas’, Histochemistry and Cell Biology, 148(4), pp. 345-357. doi: 10.1007/s00418-017-1580-6.   edoc
Pratsinis, A., Kelesidis, G. A., Zuercher, S., Krumeich, F., Bolisetty, S., Mezzenga, R., Leroux, J.-C. and Sotiriou, G. A. (2017) ‘Enzyme-Mimetic Antioxidant Luminescent Nanoparticles for Highly Sensitive Hydrogen Peroxide Biosensing’, ACS nano, 11(12), pp. 12210-12218. doi: 10.1021/acsnano.7b05518.   edoc
Luciani, P., Estella-Hermoso de Mendoza, A., Casalini, T., Lang, S., Atrott, K., Spalinger, M. R., Pratsinis, A., Sobek, J., Frey-Wagner, I., Schumacher, J., Leroux, J.-C. and Rogler, G. (2017) ‘Gastroresistant oral peptide for fluorescence imaging of colonic inflammation’, Journal of controlled release, 262, pp. 118-126. doi: 10.1016/j.jconrel.2017.07.024.   edoc
Pratsinis, A., Zuercher, S., Forster, V., Fischer, E. J., Luciani, P. and Leroux, J.-C. (2017) ‘Liposome-supported enzymatic peritoneal dialysis’, Biomaterials, 145, pp. 128-137. doi: 10.1016/j.biomaterials.2017.08.016.   edoc
Dürr, S., Hersberger, K. E., Zeller, A., Scheuzger, J., Miedinger, D., Gregoriano, C., Joos Zellweger, L., Steurer-Stey, C. and Leuppi, J. D. (2017) ‘The Integrated Care of Asthma in Switzerland (INCAS) Study: Changes in Asthma Control and Perception of Health Care through Asthma Education’, Respiration. Karger, 94(5), pp. 416-423. doi: 10.1159/000478945.   edoc
Fabienne Böni (2017) ‘Barriers and Facilitators for Information Exchange during Over-The-Counter Consultations in Community Pharmacy: A Focus Group Study’, Pharmacy. MDPI, 5(4), p. 64. doi: 10.3390/pharmacy5040065.   edoc | Open Access
Wilson, J. C., Sarsour, K., Collinson, N., Tuckwell, K., Musselman, D., Klearman, M., Napalkov, P., Jick, S. S., Stone, J. H. and Meier, C. R. (2017) ‘Serious adverse effects associated with glucocorticoid therapy in patients with giant cell arteritis (GCA): A nested case-control analysis’, Seminars in Arthritis and Rheumatism. Elsevier, 46(6), pp. 819-827. doi: 10.1016/j.semarthrit.2016.11.006.   edoc
Biétry, F. A., Pfeil, A. M., Reich, O., Schwenkglenks, M. and Meier, C. R. (2017) ‘Benzodiazepine Use and Risk of Developing Alzheimer’s Disease: A Case-Control Study Based on Swiss Claims Data’, CNS Drugs. Springer, 31(3), pp. 245-251. doi: 10.1007/s40263-016-0404-x.   edoc
Meier, C. R. (2017) ‘Rosacea, inflammatory bowel disease and the value of big data and of epidemiological studies’, British Journal of Dermatology. Wiley, 176(1), pp. 9-10. doi: 10.1111/bjd.15168.   edoc
Meier, C. R. and Jick, S. S. (2017) ‘Antenatal Exposure and Diseases in the Offspring: The Role of Big Data’, Drug Safety. Springer, 40(5), pp. 363-364. doi: 10.1007/s40264-017-0514-5.   edoc
Frey, N., Hügle, T., Jick, S. S., Meier, C. R. and Spoendlin, J. (2017) ‘Hyperlipidaemia and incident osteoarthritis of the hand: a population-based case-control study’, Osteoarthritis and Cartilage. Elsevier, 25(7), pp. 1040-1045. doi: 10.1016/j.joca.2017.01.014.   edoc

2016

Moradi-Afrapoli, F., Oufir, M., Walter, F. R., Deli, M. A., Smieško, M., Zabela, V., Butterweck, V. and Hamburger, M. (2016) ‘Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro BBB and intestinal drug permeability studies’, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 264-274. doi: 10.1016/j.jpba.2016.05.039.   edoc
Jähne, E. A., Sampath, C., Butterweck, V., Hamburger, M. and Oufir, M. (2016) ‘Development and full validation of an UPLC-MS/MS method for the quantification of indirubin in rat plasma’, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 247-252. doi: 10.1016/j.jpba.2016.05.018.   edoc
Kettiger, H., Québatte, G., Perrone, B. and Huwyler, J. (2016) ‘Interactions between silica nanoparticles and phospholipid membranes’, Biochimica et biophysica acta. Elsevier, 1858(9), pp. 2163-2170. doi: 10.1016/j.bbamem.2016.06.023.   edoc
Hussner, J., Sünwoldt, J., Seibert, I., Gliesche, D. G. and Meyer zu Schwabedissen, H. E. (2016) ‘Pimecrolimus increases the expression of interferon-inducible genes that modulate human coronary artery cells proliferation’, European Journal of Pharmacology. Elsevier, 784, pp. 137-146. doi: 10.1016/j.ejphar.2016.05.020.   edoc
Buck, J., Huwyler, J., Kühl, P. and Dischinger, A. (2016) ‘Pediatric Dispersible Tablets: a Modular Approach for Rapid Prototyping’, Pharmaceutical research. Plenum Press, 33(8), pp. 2043-2055. doi: 10.1007/s11095-016-1946-9.   edoc
Preisig, D., Roth, R., Tognola, S., Varum, F. J. O., Bravo, R., Cetinkaya, Y., Huwyler, J. and Puchkov, M. (2016) ‘Mucoadhesive microparticles for local treatment of gastrointestinal diseases’, European journal of pharmaceutics and biopharmaceutics. Elsevier, 105, pp. 156-165. doi: 10.1016/j.ejpb.2016.06.009.   edoc
Gliesche, D. G., Hussner, J., Witzigmann, D., Porta, F., Glatter, T., Schmidt, A., Huwyler, J. and Meyer Zu Schwabedissen, H. E. (2016) ‘Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries’, Molecular Pharmaceutics. American Chemical Society, 13(7), pp. 2290-2300. doi: 10.1021/acs.molpharmaceut.6b00033.   edoc
Bischoff, T., Vogl, C. R., Ivemeyer, S., Klarer, F., Meier, B., Hamburger, M. and Walkenhorst, M. (2016) ‘Plant and natural product based household remedies manufactured and used by farmers of six central Swiss cantons to treat livestock’, Livestock science. Elsevier, 189, pp. 110-125. doi: 10.1016/j.livsci.2016.05.003.   edoc
Hu, Z., Wahl, J., Hamburger, M. and Vedani, A. (2016) ‘Molecular mechanisms of endocrine and metabolic disruption: An in silico study on antitrypanosomal natural products and some derivatives’, Toxicology Letters. Elsevier, 252, pp. 29-41. doi: 10.1016/j.toxlet.2016.04.013.   edoc
Eigenmann, D. E., Dürig, C., Jähne, E. A., Smieško, M., Culot, M., Gosselet, F., Cecchelli, R., Cederberg Helms, H. C., Brodin, B., Wimmer, L., Mihovilovic, M. D., Hamburger, M. and Oufir, M. (2016) ‘In vitro blood-brain barrier permeability predictions of piperine analogues with GABAA receptor modulating properties’, European Journal of Pharmaceutics and Biopharmaceutics. Elsevier, 103, pp. 118-126. doi: 10.1016/j.ejpb.2016.03.029.   edoc
Witzigmann, D., Quagliata, L., Schenk, S. H., Quintavalle, C., Terracciano, L. M. and Huwyler, J. (2016) ‘Variable asialoglycoprotein-receptor 1 expression in liver disease: Implications for therapeutic intervention’, Hepatology research . Blackwell, 46(7), pp. 686-696. doi: 10.1111/hepr.12599.   edoc
Eberle, V. A., Häring, A., Schoelkopf, J., Gane, P. A. C., Huwyler, J. and Puchkov, M. (2016) ‘In silico and in vitro methods to optimize the performance of experimental gastroretentive floating mini-tablets’, Drug development and industrial pharmacy. Informa Healthcare, 42(5), pp. 808-817. doi: 10.3109/03639045.2015.1078350.   edoc
Canonica, J., Sergi, C., Maillard, M., Klusonova, P., Odermatt, A., Koesters, R., Loffing-Cueni, D., Loffing, J., Rossier, B., Frateschi, S. and Hummler, E. (2016) ‘Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype’, Pflügers Archiv : European journal of physiology. Springer, 468(5), pp. 895-908. doi: 10.1007/s00424-015-1785-2.   edoc
Mani, O., Nashev, L. G., Livelo, C., Baker, M. E. and Odermatt, A. (2016) ‘Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone’, The Journal of steroid biochemistry and molecular biology. Elsevier, 159, pp. 31-40. doi: 10.1016/j.jsbmb.2016.02.017.   edoc
Riede, J., Poller, B., Umehara, K.- ichi, Huwyler, J. and Camenisch, G. (2016) ‘New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data’, European journal of pharmaceutical sciences. Elsevier, 86, pp. 96-102. doi: 10.1016/j.ejps.2016.02.022.   edoc
Odermatt, A., Strajhar, P. and Engeli, R. T. (2016) ‘Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools’, The Journal of steroid biochemistry and molecular biology. Elsevier, 158, pp. 9-21. doi: 10.1016/j.jsbmb.2016.01.009.   edoc
Grabe, H. J., Wittfeld, K., Van der Auwera, S., Janowitz, D., Hegenscheid, K., Habes, M., Homuth, G., Barnow, S., John, U., Nauck, M., Völzke, H., Meyer zu Schwabedissen, H. E., Freyberger, H. J. and Hosten, N. (2016) ‘Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample’, Human brain mapping. Wiley-Liss, 37(4), pp. 1602-1613. doi: 10.1002/hbm.23123.   edoc
Bloechliger, M., Ceschi, A., Rüegg, S., Kupferschmidt, H., Krähenbühl, S., Jick, S. S., Meier, C. R. and Bodmer, M. (2016) ‘Risk of Seizures Associated with Antidepressant Use in Patients with Depressive Disorder: Follow-up Study with a Nested Case-Control Analysis Using the Clinical Practice Research Datalink’, Drug Safety . Springer, 39(4), pp. 307-321. doi: 10.1007/s40264-015-0363-z.   edoc
Seliger, C., Meier, C. R., Jick, S. S., Uhl, M., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) ‘Use of cardiac glycosides and risk of glioma’, Journal of Neuro-Oncology . Springer Science+Business Media B.V., 127(2), pp. 321-328. doi: 10.1007/s11060-015-2036-2.   edoc
Ramming, T., Kanemura, S., Okumura, M., Inaba, K. and Appenzeller-Herzog, C. (2016) ‘Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover’, Redox biology. Elsevier, 7, pp. 14-20. doi: 10.1016/j.redox.2015.11.004.   edoc
Strajhar, P., Schmid, Y., Liakoni, E., Dolder, P. C., Rentsch, K. M., Kratschmar, D. V., Odermatt, A. and Liechti, M. E. (2016) ‘Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects’, Journal of Neuroendocrinology. Wiley, 28(3), p. 12374. doi: 10.1111/jne.12374.   edoc | Open Access
Coqueiro, A., Choi, Y. H., Verpoorte, R., Sankar Gupta, K. B. S., De Mieri, M., Hamburger, M., Marx Young, M. C., Stapleton, P., Gibbons, S. and da Silva Bolzani, V. (2016) ‘Anti-staphylococcal prenylated acylphoroglucinol and xanthones from Kielmeyera variabilis (Clusiaceae)’, Journal of natural products. American Society of Pharmacognosy, 79(3), pp. 470-476. doi: 10.1021/acs.jnatprod.5b00858.   edoc
Eigenmann, D. E., Jähne, E. A., Smiesko, M., Hamburger, M. and Oufir, M. (2016) ‘Validation of an immortalized human (hBMEC) in vitro blood-brain barrier model’, Analytical and Bioanalytical Chemistry. Springer, 408(8), pp. 2095-2107. doi: 10.1007/s00216-016-9313-6.   edoc
Seliger, C., Ricci, C., Meier, C. R., Bodmer, M., Jick, S. S., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) ‘Diabetes, use of antidiabetic drugs, and the risk of glioma’, Neuro-Oncology. Oxford University Press, 18(3), pp. 340-349. doi: 10.1093/neuonc/nov100.   edoc | Open Access
Bornand, D., Toovey, S., Jick, S. S. and Meier, C. R. (2016) ‘The risk of new onset depression in association with influenza - a population-based observational study’, Brain, Behavior and Immunity . Elsevier, 53, pp. 131-137. doi: 10.1016/j.bbi.2015.12.005.   edoc
Requena, G., Huerta, C., Gardarsdottir, H., Logie, J., González-González, R., Abbing-Karahagopian, V., Miret, M., Schneider, C., Souverein, P. C., Webb, D., Afonso, A., Boudiaf, N., Martin, E., Oliva, B., Alvarez, A., De Groot, M. C. H., Bate, A., Johansson, S., Schlienger, R., Reynolds, R., Klungel, O. H. and de Abajo, F. J. (2016) ‘Hip/femur fractures associated with the use of benzodiazepines (anxiolytics, hypnotics and related drugs): a methodological approach to assess consistencies across databases from the PROTECT-EU project’, Pharmacoepidemiology and drug safety. John Wiley, 25(1), pp. 66-78. doi: 10.1002/pds.3816.   edoc
Huerta, C., Abbing-Karahagopian, V., Requena, G., Oliva, B., Alvarez, Y., Gardarsdottir, H., Miret, M., Schneider, C., Gil, M., Souverein, P. C., De Bruin, M. L., Slattery, J., De Groot, M. C. H., Hesse, U., Rottenkolber, M., Schmiedl, S., Montero, D., Bate, A., Ruigomez, A., García-Rodríguez, L. A., Johansson, S., de Vries, F., Schlienger, R. G., Reynolds, R. F., Klungel, O. H. and de Abajo, F. J. (2016) ‘Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project’, Pharmacoepidemiology and drug safety. John Wiley, 25(1), pp. 56-65. doi: 10.1002/pds.3825.   edoc
Spoendlin, J., Karatas, G., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) ‘Rosacea in Patients with Ulcerative Colitis and Crohn’s Disease: a Population-based Case-control Study’, Inflammatory Bowel Diseases. Lippincott Williams & Wilkins, 22(3), pp. 680-687. doi: 10.1097/MIB.0000000000000644.   edoc
Corradi, E., De Mieri, M., Cadisch, L., Abbet, C., Hamburger, M. and Potterat, O. (2016) ‘New Acylated Flavonol Glycosides and a Phenolic Profile of Pritzelago alpina, a Forgotten Edible Alpine Plant ’, Chemistry & Biodiversity. Helvetica Chimica Acta, 13(2), pp. 188-197. doi: 10.1002/cbdv.201500353.   edoc
Ríos Quiroz, A., Lamerz, J., De Cunha, T., Boillon, A., Adler, M., Finkler, C., Huwyler, J., Schmidt, R., Mahler, H.-C. and Koulov, A. V. (2016) ‘Factors Governing the Precision of Subvisible Particle Measurement Methods - A Case Study with a Low-Concentration Therapeutic Protein Product in a Prefilled Syringe’, Pharmaceutical research. Springer, 33(2), pp. 450-461. doi: 10.1007/s11095-015-1801-4.   edoc
Wilson, J. C., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) ‘Inflammatory Bowel Disease and the Risk of Autoimmune Diseases’, Journal of Crohn’s and Colitis. Elsevier, 10(2), pp. 186-193. doi: 10.1093/ecco-jcc/jjv193.   edoc
Mathaes, R., Mahler, H.-C., Buettiker, J.-P., Roehl, H., Lam, P., Brown, H., Luemkemann, J., Adler, M., Huwyler, J., Streubel, A. and Mohl, S. (2016) ‘The pharmaceutical vial capping process; Container closure systems, capping equipment, regulatory framework, and seal quality tests’, European journal of pharmaceutics and biopharmaceutics. Elsevier, 99, pp. 54-64. doi: 10.1016/j.ejpb.2015.11.016.   edoc
Rizner, T. L., Sasano, H., Choi, M. H., Odermatt, A. and Adamski, J. (2016) ‘Recommendations for description and validation for antibodies for research use’, The journal of steroid biochemistry and molecular biology. Pergamon, 156, pp. 40-42. doi: 10.1016/j.jsbmb.2015.11.021.   edoc
Pouw, R. B., Brouwer, M. C., Geissler, J., van Herpen, L. V., Zeerleder, S. S., Wuillemin, W. A., Wouters, D. and Kuijpers, T. W. (2016) ‘Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3’, PLoS ONE. Public Library of Science, 11(3), p. e0152164. doi: 10.1371/journal.pone.0152164.   edoc
Schäfer, N., Grosche, A., Reinders, J., Hauck, S. M., Pouw, R. B., Kuijpers, T. W., Wouters, D., Ehrenstein, B., Enzmann, V., Zipfel, P. F., Skerka, C. and Pauly, D. (2016) ‘Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases’, Frontiers in immunology. Frontiers Media, 7, p. 542. doi: 10.3389/fimmu.2016.00542.   edoc
Bonifacio, A., Mullen, P. J., Mityko, I. S., Navegantes, L. C., Bouitbir, J. and Krähenbühl, S. (2016) ‘Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo’, Archives of Toxicology, 90(1), pp. 203-215. doi: 10.1007/s00204-014-1378-4.   edoc
Seliger, C., Meier, C. R., Becker, C., Jick, S. S., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) ‘Statin use and risk of glioma: population-based case–control analysis’, European Journal of Epidemiology. Springer Science+Business Media B.V., pp. 947-952. doi: 10.1007/s10654-016-0145-7.   edoc
Novakova, K., Kummer, O., Bouitbir, J., Stoffel, S. D., Hoerler-Koerner, U., Bodmer, M., Roberts, P., Urwyler, A., Ehrsam, R. and Krähenbühl, S. (2016) ‘Effect of l-carnitine supplementation on the body carnitine pool, skeletal muscle energy metabolism and physical performance in male vegetarians’, European Journal of Nutrition, 55(1), pp. 207-217. doi: 10.1007/s00394-015-0838-9.   edoc
Arnet, I., Kooij, M. J., Messerli, M., Hersberger, K. E., Heerdink, E. R. and Bouvy, M. (2016) ‘Proposal of standardization to assess adherence with medication records: methodology matters’, Annals of Pharmacotherapy. SAGE Publications, 50(5), pp. 360-368. doi: 10.1177/1060028016634106.   edoc | Open Access
Meyer-Massetti, C., Krummenacher, E., Hedinger-Grogg, B., Luterbacher, S. and Hersberger, K. E. (2016) ‘Medikationssicherheit im Home Care Bereich: Entwicklung und Pilotierung eines Critical Incident Reporting Systems ’, Pflege. Hogrefe, 29(5), pp. 247-255. doi: 10.1024/1012-5302/a000498.   edoc

2015

Kettiger, H., Karaman, D. S., Schiesser, L., Rosenholm, J. M. and Huwyler, J. (2015) ‘Comparative safety evaluation of silica-based particles’, Toxicology in vitro. Elsevier, 30(1), pp. 355-363. doi: 10.1016/j.tiv.2015.09.030.   edoc
Moghadam, S. E., Ebrahimi, S. N., Gafner, F., Ochola, J. B., Marubu, R. M., Lwande, W., Frei Haller, B., Salehi, P. and Hamburger, M. (2015) ‘Metabolite profiling for caffeic acid oligomers in Satureja biflora’, Industrial Crops and Products. Elsevier, 76, pp. 892-899. doi: 10.1016/j.indcrop.2015.07.059.   edoc
Arnet, I., Altermatt, M., Roggo, Y. and Schnetzler, G. (2015) ‘Pharmaceutical quality of eight generics of ceftriaxone preparation for injection in Eastern Asia’, Journal of chemotherapy . Taylor & Francis Group, 27(6), pp. 337-342. doi: 10.1179/1973947814Y.0000000208.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) ‘Association of hormone therapy and incident gout: population-based case-control study’, Menopause. Lippincott, 22(12), pp. 1335-1342. doi: 10.1097/GME.0000000000000474.   edoc
Favre-Godal, Q., Dorsaz, S., Queiroz, E. F., Marcourt, L., Ebrahimi, S. N., Allard, P.-M., Voinesco, F., Hamburger, M., Gupta, M. P., Gindro, K., Sanglard, D. and Wolfender, J.-L. (2015) ‘Identification of novel anti-Candida cassane type diterpenes from the roots bark of Swartzia simplex (Sw.) Spreng’, Journal of Natural Products. American Chemical Society, 78(12), pp. 2994-3004. doi: 10.1021/acs.jnatprod.5b00744.   edoc
Arnet, I., Seidling, H. M. and Hersberger, K. E. (2015) ‘Unerwünschte Arzneimittelwirkungen in der Offizinapotheke’, Therapeutische Umschau. Hans Huber, 72(11/12), pp. 687-692. doi: 10.1024/0040-5930/a000738.   edoc
Folzer, E., Khan, T., Schmidt, R., Finkler, C., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) ‘Determination of the Density of Protein Particles Using a Suspended Microchannel Resonator’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(12), pp. 4034-4040. doi: 10.1002/jps.24635.   edoc
Boll, B., Folzer, E., Finkler, C., Huwyler, J., Mahler, H.-C., Schmidt, R. and Koulov, A. V. (2015) ‘Comparative Evaluation of Two Methods for Preparative Fractionation of Proteinaceous Subvisible Particles-Differential Centrifugation and FACS’, Pharmaceutical research. Springer, 32(12), pp. 3952-3964. doi: 10.1007/s11095-015-1755-6.   edoc
Kaserer, T., Beck, K., Akram, M., Odermatt, A. and Schuster, D. (2015) ‘Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases’, Molecules. MDPI, 20(12), pp. 22799-22832. doi: 10.3390/molecules201219880.   edoc
Shelton, L. M., Lister, A., Walsh, J., Jenkins, R. E., Wong, M. H. L., Rowe, C., Ricci, E., Ressel, L., Fang, Y., Demougin, P., Vukojevic, V., O’Neill, P. M., Goldring, C. E., Kitteringham, N. R., Park, B. K., Odermatt, A. and Copple, I. M. (2015) ‘Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney’, Kidney international. Springer, 88(6), pp. 1261-1273. doi: 10.1038/ki.2015.286.   edoc
Becker, C., Wilson, J. C., Jick, S. S. and Meier, C. R. (2015) ‘Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: a case-control analysis’, International journal of cancer. Alan R. Liss, 137(10), pp. 2424-2431. doi: 10.1002/ijc.29601.   edoc
Seibert, J. K., Quagliata, L., Quintavalle, C., Hammond, T. G., Terracciano, L. and Odermatt, A. (2015) ‘A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer’, Cancer medicine. Wiley, 4(11), pp. 1717-1729. doi: 10.1002/cam4.517.   edoc
Di Chiara, M., Glaudemans, B., Loffing-Cueni, D., Odermatt, A., Al-Hasani, H., Devuyst, O., Faresse, N. and Loffing, J. (2015) ‘Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney’, American journal of physiology. Gastrointestinal and liver physiology. American Physiological Society, 309(9), pp. F779-F790. doi: 10.1152/ajprenal.00139.2015.   edoc
Becker, C., Jick, S. S., Meier, C. R. and Bodmer, M. (2015) ‘No evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: a case-control study’, BMC cancer. BioMed Central, 15, p. 719. doi: 10.1186/s12885-015-1719-6.   edoc
Haegler, P., Grünig, D., Berger, B., Krähenbühl, S. and Bouitbir, J. (2015) ‘Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: a cell model for idiosyncratic toxicity’, Toxicology. Elsevier, 336, pp. 48-58. doi: 10.1016/j.tox.2015.07.015.   edoc
Imfeld, P., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) ‘Benzodiazepine Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case-Control Analysis’, Drug safety. Adis International, 38(10), pp. 909-919. doi: 10.1007/s40264-015-0319-3.   edoc
Glanzmann, C., Frey, B., Meier, C. R. and Vonbach, P. (2015) ‘Analysis of medication prescribing errors in critically ill children’, European journal of pediatrics. Springer, 174(10), pp. 1347-1355. doi: 10.1007/s00431-015-2542-4.   edoc
Welzenbach, K., Mancuso, R. V., Krähenbühl, S. and Weitz-Schmidt, G. (2015) ‘A novel multi-parameter assay to dissect the pharmacological effects of different modes of integrin αLβ2 inhibition in whole blood’, British journal of pharmacology. Nature Publishing Group, 172(20), pp. 4875-4887. doi: 10.1111/bph.13256.   edoc
Allmendinger, A., Mueller, R., Huwyler, J., Mahler, H.-C. and Fischer, S. (2015) ‘Sterile Filtration of Highly Concentrated Protein Formulations: Impact of Protein Concentration, Formulation Composition, and Filter Material’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(10), pp. 3319-3329. doi: 10.1002/jps.24561.   edoc
Farimani, M. M., Bahadori, M. B., Koulaei, S. A., Salehi, P., Ebrahimi, S. N., Khavasi, H. R. and Hamburger, M. (2015) ‘New ursane triterpenoids from Salvia urmiensis Bunge: absolute configuration and anti-proliferative activity’, Fitoterapia. Elsevier, 106, pp. 1-6. doi: 10.1016/j.fitote.2015.07.017.   edoc
Du, K., De Mieri, M., Neuburger, M., Zietsman, P. C., Marston, A., van Vuuren, S. F., Ferreira, D., Hamburger, M. and van der Westhuizen, J. H. (2015) ‘Labdane and clerodane diterpenes from Colophospermum mopane’, Journal of Natural Products. American Chemical Society, 78(10), pp. 2494-2504. doi: 10.1021/acs.jnatprod.5b00729.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) ‘Poorly controlled type 2 diabetes mellitus is associated with a decreased risk of incident gout: a population-based case-control study’, Annals of the rheumatic diseases. British Medical Association, 74(9), pp. 1651-1658. doi: 10.1136/annrheumdis-2014-205337.   edoc
Werk, T., Huwyler, J., Hafner, M., Luemkemann, J. and Mahler, H.-C. (2015) ‘An Impedance-Based Method to Determine Reconstitution Time for Freeze-Dried Pharmaceuticals’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2948-2955. doi: 10.1002/jps.24443.   edoc
Folzer, E., Diepold, K., Bomans, K., Finkler, C., Schmidt, R., Bulau, P., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) ‘Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2824-2831. doi: 10.1002/jps.24509.   edoc
Kunze, A., Poller, B., Huwyler, J. and Camenisch, G. (2015) ‘Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins’, Drug Metabolism and Personalized Therapy. de Gruyter, 30(3), pp. 175-188. doi: 10.1515/dmdi-2015-0003.   edoc
Hussner, J., Begung, R., Boettcher, K., Gliesche, D. G., Prestin, K. and Meyer zu Schwabedissen, H. E. (2015) ‘Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery’, Vascular Pharmacology . Elsevier, 72, pp. 25-34. doi: 10.1016/j.vph.2015.06.006.   edoc
Moridi Farimani, M., Abbas-Mohammadi, M., Esmaeili, M.-A., Salehi, P., Nejad-Ebrahimi, S., Sonboli, A. and Hamburger, M. (2015) ‘Seco-ursane type triterpenoids from Salvia urmiensis with apoptosis-inducing activity’, Planta medica. Thieme, 81(14), pp. 1290-1295. doi: 10.1055/s-0035-1546256.   edoc
Wilson, J. C., Toovey, S., Jick, S. S. and Meier, C. R. (2015) ‘Previously diagnosed influenza infections and the risk of developing epilepsy’, Epidemiology and infection. Cambridge University Press, 143(11), pp. 2408-2415. doi: 10.1017/S0950268814003380.   edoc
Bonifacio, A., Sanvee, G. M., Bouitbir, J. and Krähenbühl, S. (2015) ‘The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity’, Biochimica et biophysica acta. Elsevier, 1853(8), pp. 1841-1849. doi: 10.1016/j.bbamcr.2015.04.010.   edoc
Roberts, P. A., Bouitbir, J., Bonifacio, A., Singh, F., Kaufmann, P., Urwyler, A. and Krähenbühl, S. (2015) ‘Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency’, American journal of physiology. Gastrointestinal and liver physiology. American Physiological Society, 309(3), pp. E265-E274. doi: 10.1152/ajpendo.00001.2015.   edoc
Liakoni, E., Rätz Bravo, A. E. and Krähenbühl, S. (2015) ‘Hepatotoxicity of New Oral Anticoagulants (NOACs)’, Drug safety. Adis International, 38(8), pp. 711-720. doi: 10.1007/s40264-015-0317-5.   edoc
Oufir, M., Seiler, C., Gerodetti, M., Gerber, J., Fürer, K., Mennet-von Eiff, M., Elsas, S.-M., Brenneisen, R., von Mandach, U., Hamburger, M. and Potterat, O. (2015) ‘Quantification of burfadienolides in bryophyllum pinnatum leaves and manufactured products by UHPLC-ESIMS/MS’, Planta Medica. Georg Thieme Verlag, 81(12/13), pp. 1190-1197. doi: 10.1055/s-0035-1546126.   edoc
Du, K., De Mieri, M., Saxena, P., Phungula, K. V., Zietsman, P. C., Hering, S., van der Westhuizen, J. H. and Hamburger, M. (2015) ‘HPLC-​Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana’, Planta Medica. Georg Thieme Verlag, 81(12/13), pp. 1154-1162. doi: 10.1055/s-0035-1545929.   edoc
Allmendinger, A., Mueller, R., Schwarb, E., Chipperfield, M., Huwyler, J., Mahler, H.-C. and Fischer, S. (2015) ‘Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection’, Pharmaceutical research. Plenum Press, 32(7), pp. 2229-2240. doi: 10.1007/s11095-014-1611-0.   edoc
Bloechliger, M., Rüegg, S., Jick, S. S., Meier, C. R. and Bodmer, M. (2015) ‘Antipsychotic drug use and the risk of seizures: follow-up study with a nested case-control analysis’, CNS drugs. Springer, 29(7), pp. 591-603. doi: 10.1007/s40263-015-0262-y.   edoc
Layton, J. B., Meier, C. R., Sharpless, J. L., Stürmer, T., Jick, S. S. and Brookhart, M. A. (2015) ‘Comparative Safety of Testosterone Dosage Forms’, JAMA internal medicine. American Medical Association, 175(7), pp. 1187-1196. doi: 10.1001/jamainternmed.2015.1573.   edoc
Singh, F., Charles, A.-L., Schlagowski, A.-I., Bouitbir, J., Bonifacio, A., Piquard, F., Krähenbühl, S., Geny, B. and Zoll, J. (2015) ‘Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis’, Biochimica et biophysica acta. Molecular cell research. Elsevier, 1853(7), pp. 1574-1585. doi: 10.1016/j.bbamcr.2015.03.006.   edoc
Ślusarczyk, S., Topolski, J., Domaradzki, K., Adams, M., Hamburger, M. and Matkowski, M. (2015) ‘Isolation and fast selective determinatino of nor-abhietanoid diterpenoids from Perovskia atriplicifolia roots using LC-ESIMS/MS with multiple reaction monitoring’, Natural Product Communications . Natural Product Incorporation , 10(7), pp. 1149-1152.   edoc
Odermatt, A. and Klusonova, P. (2015) ‘11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story’, The journal of steroid biochemistry and molecular biology. Pergamon, 151, pp. 85-92. doi: 10.1016/j.jsbmb.2014.08.011.   edoc
Tsachaki, M., Birk, J., Egert, A. and Odermatt, A. (2015) ‘Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions’, Biochimica et biophysica acta. Molecular cell research. Elsevier, 1853(7), pp. 1672-1682. doi: 10.1016/j.bbamcr.2015.04.002.   edoc