2020

Schneider, R., Reinau, D., Schur, N., Blozik, E., Früh, M., Signorell, A., Heininger, U., Schwenkglenks, M. and Meier, C. R. (2020) ‘Coverage rates and timeliness of nationally recommended vaccinations in Swiss preschool children: A descriptive analysis using claims data ’, Vaccine. Elsevier, 38(6), pp. 1551-1558. doi: 10.1016/j.vaccine.2019.11.057.   edoc
Pironi, L., Boeykens, K., Bozzetti, F., Joly, F., Klek, S., Lal, S., Lichota, M., Mühlebach, S., Van Gossum, A., Wanten, G., Wheatley, C. and Bischoff, S. C. (2020) ‘ESPEN guideline on home parenteral nutrition’, Clinical Nutrition. Elsevier, 39(6), pp. 1645-1666. doi: 10.1016/j.clnu.2020.03.005.   edoc | Open Access
Don, C. G. and Smieško, M. (2020) ‘In Silico Pharmacogenetics CYP2D6 Study Focused on the Pharmacovigilance of Herbal Antidepressants’, Frontiers in Pharmacology. Frontiers Media, 11, p. 683. doi: 10.3389/fphar.2020.00683.   edoc | Open Access
Liu, J., Craciun, I., Belluati, A., Wu, D., Sieber, S., Einfalt, T., Witzigmann, D., Chami, M., Huwyler, J. and Palivan, C. G. (2020) ‘DNA-directed arrangement of soft synthetic compartments and their behavior in vitro and in vivo’, Nanoscale. Royal Society of Chemistry, 12(17), pp. 9786-9799. doi: 10.1039/d0nr00361a.   edoc | Open Access
Lizák, B., Birk, J., Zana, M., Kosztyi, G., Kratschmar, D. V., Odermatt, A., Zimmermann, R., Geiszt, M., Appenzeller-Herzog, C. and Bánhegyi, G. (2020) ‘Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione’, BMC Biology. BioMed Central, 18(1), p. 19. doi: 10.1186/s12915-020-0749-y.   edoc | Open Access
Einfalt, T., Garni, M., Witzigmann, D., Sieber, S., Baltisberger, N., Huwyler, J., Meier, W. and Palivan, C. (2020) ‘Bioinspired Molecular Factories with Architecture and In Vivo Functionalities as Cell Mimics’, Advanced Science. Wiley, 7(4), p. 1901923. doi: 10.1002/advs.201901923.   edoc | Open Access
Schuster, J., Koulov, A., Mahler, H.-C., Joerg, S., Huwyler, J., Schleicher, K., Detampel, P. and Mathaes, R. (2020) ‘Particle Analysis of Biotherapeutics in Human Serum Using Machine Learning’, Journal of Pharmaceutical Sciences, 109, pp. 1827-1832. doi: 10.1016/j.xphs.2020.02.015.   
Schuster, J., Mahler, H.-C., Koulov, A., Joerg, S., Racher, A., Huwyler, J., Detampel, P. and Mathaes, R. (2020) ‘Tracking the physical stability of fluorescent-labeled mAbs under physiologic invitro conditions in human serum and PBS’, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 152, pp. 193-201. doi: 10.1016/j.ejpb.2020.04.014.   
Burkard, T., Rauch, M., Spoendlin, J., Prieto-Alhambra, D., Jick, S. S. and Meier, C. R. (2020) ‘Risk of hand osteoarthritis in new users of hormone replacement therapy: A nested case-control analysis’, Maturitas, 132, pp. 17-23. doi: 10.1016/j.maturitas.2019.11.006.   
Lederer, A.-K., Maul-Pavicic, A., Hannibal, L., Hettich, M., Steinborn, C., Gründemann, C., Zimmermann-Klemd, A. M., Müller, A., Sehnert, B., Salzer, U., Klein, R., Voll, R. E., Samstag, Y. and Huber, R. (2020) ‘Vegan diet reduces neutrophils, monocytes and platelets related to branched-chain amino acids - A randomized, controlled trial’, Clinical nutrition (Edinburgh, Scotland), p. Epub ahead of print. doi: 10.1016/j.clnu.2020.02.011.   
Tsachaki, M., Strauss, P., Dunkel, A., Navrátilová, H., Mladenovic, N. and Odermatt, A. (2020) ‘Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration’, Cellular and molecular life sciences : CMLS, 77(6), pp. 1153-1175. doi: 10.1007/s00018-019-03227-w.   
Fischer, A. and Smieško, M. (2020) ‘Allosteric Binding Sites On Nuclear Receptors: Focus On Drug Efficacy and Selectivity’, International journal of molecular sciences, 21(2), p. 534. doi: 10.3390/ijms21020534.   
Yokoyama, R., Kimura, G., Huwyler, J., Hosoya, K.- ichi and Puchkov, M. (2020) ‘Impact of Insoluble Separation Layer Mechanical Properties on Disintegration and Dissolution Kinetics of Multilayer Tablets’, pharmaceutics, 12(495), p. 12060495. doi: 10.3390/pharmaceutics12060495.   
Dreckmann, T., Ludwig, I.-S., Boeuf, J., Lümkemann, J. and Huwyler, J. (2020) ‘Low Volume Aseptic Filling: Impact of Pump Systems on Shear Stress’, European Journal of Pharmaceutics and Biopharmaceutics, 147, pp. 10-18. doi: 10.1016/j.ejpb.2019.12.006.   
Suenderhauf, C., Berger, B., Puchkov, M., Schmid, Y., Müller, S., Huwyler, J., Haschke, M., Krähenbühl, S. and Duthaler, U. (2020) ‘Pharmacokinetics and phenotyping properties of the “Basel” phenotyping cocktail combination capsule in healthy male adults’, British journal of clinical pharmacology, pp. 1-10. doi: 10.1111/bcp.14157.   
Randi, E. B., Vervaet, B., Tsachaki, M., Porto, E., Vermeylen, S., Lindenmeyer, M. T., Thuy, L. T. T., Cohen, C. D., Devuyst, O., Kistler, A. D., Szabo, C., Kawada, N., Hankeln, T., Odermatt, A., Dewilde, S., Wenger, R. H. and Hoogewijs, D. (2020) ‘The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease’, Antioxidants & redox signaling, 32(16), pp. 1155-1171. doi: 10.1089/ars.2019.7868.   
Häuser, C., Goldbach, P., Huwyler, J., Friess, W. and Allmendinger, A. (2020) ‘Excipients for Room Temperature Stable Freeze-Dried Monoclonal Antibody Formulations’, Journal of Pharmaceutical Sciences, 109, pp. 807-817. doi: 10.1016/j.xphs.2019.10.016.   
Nguyen, M.-V. H., Davis, M. R., Wittenberg, R., Mchardy, I., Baddley, J. W., Young, B. Y., Odermatt, A. and Thompson, G. R. (2020) ‘Posaconazole Serum Drug Levels Associated With Pseudohyperaldosteronism’, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 70(12), pp. 2593-2598. doi: 10.1093/cid/ciz741.   
Sedighi, M., Rahimi, F., Shahbazi, M.-A., Rezayan, A. H., Kettiger, H., Einfalt, T., Huwyler, J. and Witzigmann, D. (2020) ‘Controlled Tyrosine Kinase Inhibitor Delivery to Liver Cancer Cells by Gate-Capped Mesoporous Silica Nanoparticles’, ACS Applied Bio Materials, 3, pp. 239-251. doi: 10.1021/acsabm.9b00772.   
Beck, K. R., Thompson, G. R. and Odermatt, A. (2020) ‘Drug-induced endocrine blood pressure elevation’, Pharmacological research, 154, p. 104311. doi: 10.1016/j.phrs.2019.104311.   
Chilczuk, T., Steinborn, C., Breinlinger, S., Zimmermann-Klemd, A. M., Huber, R., Enke, H., Enke, D., Niedermeyer, T. H. J. and Gründemann, C. (2020) ‘Hapalindoles from the Cyanobacterium Hapalosiphon sp. Inhibit T Cell Proliferation’, Planta medica, 86(2), pp. 96-103. doi: 10.1055/a-1045-5178.   
Inderbinen, S. G., Engeli, R. T., Rohrer, S. R., Di Renzo, E., Aengenheister, L., Buerki-Thurnherr, T. and Odermatt, A. (2020) ‘Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α’, Toxicology letters, 322, pp. 39-49. doi: 10.1016/j.toxlet.2020.01.001.   
Cörek, E., Rodgers, G., Siegrist, S., Einfalt, T., Detampel, P., Schlepütz, C. M., Sieber, S., Fluder, P., Schulz, G., Unterweger, H., Alexiou, C., Müller, B., Puchkov, M. and Huwyler, J. (2020) ‘Shedding Light on Metal-Based Nanoparticles in Zebrafish by Computed Tomography with Micrometer Resolution’, Small, 2000746, pp. 1-10. doi: 10.1002/smll.202000746.   
Patt, M., Beck, K. R., Di Marco, T., Jäger, M.-C., González-Ruiz, V., Boccard, J., Rudaz, S., Hartmann, R. W., Salah, M., van Koppen, C. J., Grill, M. and Odermatt, A. (2020) ‘Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis’, Biochemical pharmacology, 172, p. 113781. doi: 10.1016/j.bcp.2019.113781.   
FitzGerald, R. E. (2020) ‘Perspective on Health Effects of Endocrine Disruptors with a Focus on Data Gaps’, Chemical research in toxicology, 33(6), pp. 1284-1291. doi: 10.1021/acs.chemrestox.9b00529.   
Schulze, F., Wehner, J., Kratschmar, D. V., Makshana, V., Meier, D. T., Häuselmann, S. P., Dalmas, E., Thienel, C., Dror, E., Wiedemann, S. J., Traub, S., Nordmann, T. M., Rachid, L., De Baat, A., Rohm, T. V., Zhao, C., Odermatt, A., Böni-Schnetzler, M. and Donath, M. Y. (2020) ‘Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes’, Scientific reports, 10(1), p. 3035. doi: 10.1038/s41598-020-59701-0.   
Schuster, J., Koulov, A., Mahler, H.-C., Detampel, P., Huwyler, J., Singh, S. and Mathaes, R. (2020) ‘In Vivo Stability of Therapeutic Proteins’, Pharmaceutical research, 37(2), p. 23. doi: 10.1007/s11095-019-2689-1.   
Schittny, A., Huwyler, J. and Puchkov, M. (2020) ‘Mechanisms of increased bioavailability through amorphous solid dispersions: a review’, Drug delivery, 27(1), pp. 110-127. doi: 10.1080/10717544.2019.1704940.   
Kroezen, B., Conti, G., Girardi, B., Cramer, J., Jiang, X., Rabbani, S., Müller, J., Kokot, M., Luisoni, E., Ricklin, D., Schwardt, O. and Ernst, B. (2020) ‘A Potent Mimetic of the Siglec-8 Ligand 6’-Sulfo-Sialyl Lewisx’, ChemMedChem, p. Online ahead of print. doi: 10.1002/cmdc.202000417.   
Wagner-Hattler, L., Québatte, G., Keiser, J., Schoelkopf, J., Schlepütz, C. M., Huwyler, J. and Puchkov, M. (2020) ‘Study of drug particle distributions within mini-tables using synchrotron X-ray microtomography and superpixel image clustering’, International Journal of Pharmaceutics, 573, p. 118827. doi: 10.1016/j.ijpharm.2019.118827.   
Ehrsam, D., Sieber, S., Oufir, M., Porta, F., Hamburger, M., Huwyler, J. and Meyer zu Schwabedissen, H. E. (2020) ‘Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9’, Bioconjugate Chemistry, 31, pp. 781-793. doi: 10.1021/acs.bioconjchem.9b00865.   
FitzGerald, R. E. (2020) ‘Adverse Outcome Pathway Bridge Building from Research to Regulation’, Chemical research in toxicology, 33(4), pp. 849-851. doi: 10.1021/acs.chemrestox.9b00527.   
Gründemann, C., Reinhardt, J. K. and Lindequist, U. (2020) ‘European medicinal mushrooms: Do they have potential for modern medicine? - An update’, Phytomedicine : international journal of phytotherapy and phytopharmacology, 66, p. 153131. doi: 10.1016/j.phymed.2019.153131.   
Zimmermann-Klemd, A. M., Reinhardt, J. K., Morath, A., Schamel, W. W., Steinberger, P., Leitner, J., Huber, R., Hamburger, M. and Gründemann, C. (2020) ‘Immunosuppressive Activity of Artemisia argyi Extract and Isolated Compounds’, frontiers in Pharmacology, 11, p. 402. doi: 10.3389/fphar.2020.00402.   
Matter, M., Mühlebach, S., Puchkov, M. and Huwyler, J. (2020) ‘[Abuse deterrent drug formulations for opioids]. Missbrauch von Opioiden und mögliche Auswege aus der Opioid-Krise’, Therapeutische Umschau. Revue therapeutique, 77(1), pp. 24-28. doi: 10.1024/0040-5930/a001147.   
Beck, K. R., Telisman, L., van Koppen, C. J., Thompson, G. R. and Odermatt, A. (2020) ‘Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals’, The Journal of steroid biochemistry and molecular biology, 199, p. 105605. doi: 10.1016/j.jsbmb.2020.105605.   
Walkenhorst, M., Leiber, F., Maeschli, A., Kapp, A. N., Spengler‐Neff, A., Faleschini, M. T., Garo, E., Hamburger, M., Potterat, O., Mayer, P., Graf-Schiller, S. and Bieber, A. (2020) ‘A multicomponent herbal feed additive improves somatic cell counts in dairy cows ‐ a two stage, multicentre, placebo‐controlled long‐term on‐farm trial’, Journal of Animal Physiology and Animal Nutrition, 104, pp. 439-452.   
Mertenat, D., Dal Cero, M., Vogl, C. R., Ivemeyer, S., Meier, B., Maeschli, A., Hamburger, M. and Wlkenhorst, M. (2020) ‘Ethnoveterinary knowledge of farmers in bilingual regions of Switzerland - is there potential to extend veterinary options to reduce antimicrobial use?’, J. Ethnopharmacol, 246, p. 112184. doi: 10.1016/j.jep.2019.112184.   
Greenland, M., Knuiman, M. W., Hung, J., Nedkoff, L., Arnet, I., Rankin, J. M., Kilkenny, M. F. and Sanfilippo, F. M. (2020) ‘Cardioprotective medication adherence in Western Australians in the first year after myocardial infarction: restricted cubic spline analysis of adherence-outcome relationships’, Scientific Reports. Nature Publishing Group, 10(1), p. 4315. doi: 10.1038/s41598-020-60799-5.   
Schmidt, A., Koulov, A., Huwyler, J., Mahler, H.-C. and Jahn, M. (2020) ‘Stabilizing Polysorbate 20 and 80 Against Oxidative Degradation’, Journal of Pharmaceutical Sciences, 109, pp. 1924-1932. doi: 10.1016/j.xphs.2020.03.003.   

2019

Farzan, M., Roth, R., Québatte, G., Schoelkopf, J., Huwyler, J. and Puchkov, M. (2019) ‘Loading of Porous Functionalized Calcium Carbonate Microparticles: Distribution Analysis with Focused Ion Beam Electron Microscopy and Mercury Porosimetry’, Pharmaceutics. MDPI, 11(1), p. 32- . doi: 10.3390/pharmaceutics11010032.   edoc
Kaur, J., Soto-Velasquez, M., Ding, Z., Ghanbarpour, A., Lill, M. A., van Rijn, R. M., Watts, V. J. and Flaherty, D. P. (2019) ‘Optimization of a 1,3,4-oxadiazole series for inhibition of Ca; 2+; /calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain’, European journal of medicinal chemistry, 162, pp. 568-585. doi: 10.1016/j.ejmech.2018.11.036.   edoc
Cassell, R. J., Mores, K. L., Zerfas, B. L., Mahmoud, A. H., Lill, M. A., Trader, D. J. and van Rijn, R. M. (2019) ‘Rubiscolins are naturally occurring G protein-biased delta opioid receptor peptides’, European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 29(3), pp. 450-456. doi: 10.1016/j.euroneuro.2018.12.013.   edoc
Bartolowits, M. D., Gast, J. M., Hasler, A. J., Cirrincione, A. M., O’Connor, R. J., Mahmoud, A. H., Lill, M. A. and Davisson, V. J. (2019) ‘Discovery of Inhibitors for Proliferating Cell Nuclear Antigen Using a Computational-Based Linked-Multiple-Fragment Screen’, ACS omega, 4(12), pp. 15181-15196. doi: 10.1021/acsomega.9b02079.   edoc
Mahmoud, A. H., Yang, Y. and Lill, M. A. (2019) ‘Improving Atom-Type Diversity and Sampling in Cosolvent Simulations Using λ-Dynamics’, Journal of chemical theory and computation, 15(5), pp. 3272-3287. doi: 10.1021/acs.jctc.8b00940.   edoc
Yang, Y., Mahmoud, A. H. and Lill, M. A. (2019) ‘Modeling of Halogen-Protein Interactions in Co-Solvent Molecular Dynamics Simulations’, Journal of chemical information and modeling, 59(1), pp. 38-42. doi: 10.1021/acs.jcim.8b00806.   edoc
Häuser, C., Goldbach, P., Huwyler, J., Friess, W. and Allmendinger, A. (2019) ‘Impact of dextran on thermal properties, product quality attributes, and monoclonal antibody stability in freeze-dried formulations ’, European Journal of Pharmaceutics and Biopharmaceutics. Elsevier, 147, pp. 45-56. doi: 10.1016/j.ejpb.2019.12.010.   edoc
Egli, J., Schmucki, R., Loos, B., Reichl, S., Grabole, N., Roller, A., Ebeling, M., Odermatt, A. and Iglesias, A. (2019) ‘The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipig’, Immunogenetics. Springer, 71(2), pp. 123-136. doi: 10.1007/s00251-018-01099-1.   edoc
Trinh, B., Hepprich, M., Betz, M. J., Burkard, T., Cavelti-Weder, C., Seelig, E., Meienberg, F., Kratschmar, D. V., Beuschlein, F., Reincke, M., Odermatt, A., Hall, M. N., Donath, M. Y. and Swierczynska, M. M. (2019) ‘Treatment of Primary Aldosteronism with mTORC1 Inhibitors’, Journal of Clinical Endocrinology and Metabolism. Oxford University Press, 104(10), pp. 4703-4714. doi: 10.1210/jc.2019-00563.   edoc
Stohler, N. A., Reinau, D., Jick, S. S., Bodmer, D. and Meier, C. R. (2019) ‘A study on the epidemiology of tinnitus in the United Kingdom ’, Clinical epidemiology. Dove medical press, 11, pp. 855-871. doi: 10.2147/CLEP.S213136.   edoc
Schneider, R., Reinau, D., Schur, N., Blozik, E., Früh, M., Signorell, A., Heininger, U., Schwenkglenks, M. and Meier, C. R. (2019) ‘Coverage rates and timeliness of nationally recommended vaccinations in Swiss preschool children: A descriptive analysis using claims data’, Vaccine. Elsevier, 38(6), pp. 1551-1558. doi: 10.1016/j.vaccine.2019.11.057.   edoc
Witzigmann, D., Uhl, P., Sieber, S., Kaufman, C., Einfalt, T., Schöneweis, K., Grossen, P., Buck, J., Ni, Y., Schenk, S. H., Hussner, J., Meyer Zu Schwabedissen, H. E., Québatte, G., Mier, W., Urban, S. and Huwyler, J. (2019) ‘Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide’, eLife. eLife Sciences Publications, 8, p. e42276. doi: 10.7554/eLife.42276.   edoc
Reinau, D., Furrer, C., Stämpfli, D., Bornand, D. and Meier, C. R. (2019) ‘Evaluation of drug-related problems and subsequent clinical pharmacists’ interventions at a Swiss university hospital’, Journal of clinical pharmacy and therapeutics, 44(6), pp. 924-931. doi: 10.1111/jcpt.13017.   edoc
Schneider, R., Reinau, D., Schur, N., Blozik, E., Früh, M., Signorell, A., Meier, C. R. and Schwenkglenks, M. (2019) ‘Drug prescription patterns, polypharmacy and potentially inappropriate medication in Swiss nursing homes: a descriptive analysis based on claims data’, Swiss medical weekly, 149, p. w20126. doi: 10.4414/smw.2019.20126.   edoc
Mueller, A. M., Meier, C. R., Jick, S. S. and Schneider, C. (2019) ‘Weight change and blood glucose concentration as markers for pancreatic cancer in subjects with new-onset diabetes mellitus: A matched case-control study’, Pancreatology. Karger, 19(4), pp. 578-586. doi: 10.1016/j.pan.2019.03.006.   edoc
Rudin, D., Spoendlin, J., Cismaru, A. L., Liakoni, E., Bonadies, N., Amstutz, U., Meier, C. R., Krähenbühl, S. and Haschke, M. (2019) ‘Metamizole-associated neutropenia: Comparison of patients with neutropenia and metamizole-tolerant patients’, European journal of internal medicine, 68, pp. 36-43. doi: 10.1016/j.ejim.2019.07.029.   edoc
Becker, C., Jick, S. S. and Meier, C. R. (2019) ‘ACE inhibitor use and risk of cataract: a case-control analysis’, The British journal of ophthalmology, 103(11), pp. 1561-1565. doi: 10.1136/bjophthalmol-2018-312980.   edoc
Burkard, T., Moser, M., Rauch, M., Jick, S. S. and Meier, C. R. (2019) ‘Utilization pattern of hormone therapy in UK general practice between 1996 and 2015: a descriptive study’, Menopause (New York, N.Y.), 26(7), pp. 741-749. doi: 10.1097/GME.0000000000001300.   edoc
Frey, N., Bodmer, M., Bircher, A., Jick, S. S., Meier, C. R. and Spoendlin, J. (2019) ‘Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Association with Commonly Prescribed Drugs in Outpatient Care Other than Anti-Epileptic Drugs and Antibiotics: A Population-Based Case-Control Study’, Drug safety, 42(1), pp. 55-66. doi: 10.1007/s40264-018-0711-x.   edoc
Vavanikunnel, J., Charlier, S., Becker, C., Schneider, C., Jick, S. S., Meier, C. R. and Meier, C. (2019) ‘Association Between Glycemic Control and Risk of Fracture in Diabetic Patients: A Nested Case-Control Study’, The Journal of Clinical Endocrinology and Metabolism. Oxford University Press, 104(5), pp. 1645-1654. doi: 10.1210/jc.2018-01879.   edoc
Seliger, C., Luber, C., Gerken, M., Schaertl, J., Proescholdt, M., Riemenschneider, M. J., Meier, C. R., Bogdahn, U., Leitzmann, M. F., Klinkhammer-Schalke, M. and Hau, P. (2019) ‘Use of metformin and survival of patients with high-grade glioma’, International Journal of Cancer. Wiley, 144(2), pp. 273-280. doi: 10.1002/ijc.31783.   edoc
Sutherland, C. S., Ademi, Z., Michaud, J., Schur, N., Lingg, M., Bhadhuri, A., Pache, T. D., Bitzer, J., Suchon, P., Albert, V., Hersberger, K. E., Tanackovic, G. and Schwenkglenks, M. (2019) ‘Economic evaluation of a novel genetic screening test for risk of venous thromboembolism compared with standard of care in women considering combined hormonal contraception in Switzerland’, BMJ open, 9(11), p. e031325. doi: 10.1136/bmjopen-2019-031325.   edoc
Damen, N. L., Van den Bemt, B. J. F., Hersberger, K. E., Papastergiou, J., Alves da Costa, F., Rydant, S., Wartenberg, N. S., Lobban, T., Arnet, I., Antoniou, S. and International Pharmacists for Anticoagulation Care Taskforce (2019) ‘Creating an interprofessional guideline to support patients receiving oral anticoagulation therapy: a Delphi exercise’, International Journal of Clinical Pharmacy, 41(4), pp. 1012-1020. doi: 10.1007/s11096-019-00844-0.   edoc
Imfeld-Isenegger, T. L., Soares, I. B., Makovec, U. N., Horvat, N., Kos, M., van Mil, F., Costa, F. A. and Hersberger, K. E. (2019) ‘Community pharmacist-led medication review procedures across Europe: Characterization, implementation and remuneration’, Research in Social and Administrative Pharmacy . Elsevier, p. j.apharm.2019.11.002. doi: 10.1016/j.sapharm.2019.11.002.   edoc
Frei, P., Hevey, R. and Ernst, B. (2019) ‘Dynamic Combinatorial Chemistry: A New Methodology Comes of Age’, Chemistry (Weinheim an der Bergstrasse, Germany), 25(1), pp. 60-73. doi: 10.1002/chem.201803365.   edoc
Sieber, S., Grossen, P., Bussmann, J., Campbell, F., Kros, A., Witzigmann, D. and Huwyler, J. (2019) ‘Zebrafish as a preclinical in vivo screening model for nanomedicines’, Advanced drug delivery reviews, (151-152), pp. 152-168. doi: 10.1016/j.addr.2019.01.001.   edoc
Albert, V., Arnet, I. and Gudka, S. (2019) ‘Comment on patient adherence to novel oral anticoagulants (NOACs) for the treatment of atrial fibrillation and occurrence of associated bleeding events: A systematic review and meta-analysis’, Current Vascular Pharmacology, 17(4), pp. 350-351. doi: 10.2174/1570161116999180613091623.   edoc
Haag, M., Gudka, S., Hersberger, K. E. and Arnet, I. (2019) ‘Do Swiss community pharmacists address the risk of sexually transmitted infections during a consultation on emergency contraception? A simulated patient study’, European Journal of Contraception and Reproductive Health Care, 24(5), pp. 407-412. doi: 10.1080/13625187.2019.1661377.   edoc
Rothen, J.-P., Hersberger, K. E. and Arnet, I. (2019) ‘Comment on “Efficacy of long-term oral vitamin B12 supplementation after total gastrectomy: results from a prospective study”’, GE Portuguese Journal of Gastroenterology, 26(3), pp. 226-227. doi: 10.1159/000495768.   edoc
Soares, I. B., Imfeld-Isenegger, T. L., Makovec, U. N., Horvat, N., Kos, M., Arnet, I., Hersberger, K. E. and Costa, F. A. (2019) ‘A survey to assess the availability, implementation rate and remuneration of pharmacist-led cognitive services throughout Europe’, Research in Social and Administrative Pharmacy, p. nn. doi: 10.1016/j.sapharm.2019.02.002.   edoc
Fernandez-Llimos, F. (2019) ‘Peer review and publication delay’, Pharmacy Practice (Granada), 17(1), p. 1502. doi: 10.18549/PharmPract.2019.1.1502.   edoc
Haag, M., Lehmann, A., Hersberger, K. E., Schneider, M.-P., Gauchet, A., Vrijens, B., Arnet, I. and Allenet, B. (2019) ‘The ABC taxonomy for medication adherence translated into French and German’, British Journal of Clinical Pharmacology, p. nn. doi: 10.1111/bcp.14172.   edoc
Arnet, I., Rothen, J.-P. and Hersberger, K. E. (2019) ‘Validation of a Novel Electronic Device for Medication Adherence Monitoring of Ambulatory Patients’, Pharmacy (Basel, Switzerland), 7(4), p. nn. doi: 10.3390/pharmacy7040155.   edoc
Gregoriano, C., Dieterle, T., Breitenstein, A.-L., Dürr, S., Baum, A., Giezendanner, S., Maier, S., Leuppi-Taegtmeyer, A., Arnet, I., Hersberger, K. E. and Leuppi, J. D. (2019) ‘Does a tailored intervention to promote adherence in patients with chronic lung disease affect exacerbations? A randomized controlled trial’, Respiratory research, 20(1), p. 273. doi: 10.1186/s12931-019-1219-3.   edoc
Lederer, A.-K., Hannibal, L., Hettich, M., Behringer, S., Spiekerkoetter, U., Steinborn, C., Gründemann, C., Zimmermann-Klemd, A. M., Müller, A., Simmet, T., Schmiech, M., Maul-Pavicic, A., Samstag, Y. and Huber, R. (2019) ‘Vitamin B12 Status Upon Short-Term Intervention with a Vegan Diet-A Randomized Controlled Trial in Healthy Participants’, Nutrients, 11(11), p. 2815. doi: 10.3390/nu11112815.   edoc
Zimmermann-Klemd, A. M., Konradi, V., Steinborn, C., Ücker, A., Falanga, C. M., Woelfle, U., Huber, R., Jürgenliemk, G., Rajbhandari, M. and Gründemann, C. (2019) ‘Influence of traditionally used Nepalese plants on wound healing and immunological properties using primary human cells in vitro’, Journal of ethnopharmacology, 235, pp. 415-423. doi: 10.1016/j.jep.2019.02.034.   edoc
Meyer zu Schwabedissen, H. and Hersberger, K. E. (2019) ‘Pharmakogenetik: Einfluss der Gene auf Medikamente’, in Personalisierte Medizin. Grundlagen für die interprofessionelle Aus-, Weiter- und Fortbildung von Gesundheitsfachleuten. Bern: Schweizerische Akademie der Medizinischen Wissenschaften (Swiss academic communications), pp. 70-76. doi: 10.5281/zenodo.3265194.   edoc
Venkataramani, V., Tanev, D. I., Strahle, C., Studier-Fischer, A., Fankhauser, L., Kessler, T., Körber, C., Kardorff, M., Ratliff, M., Xie, R., Horstmann, H., Messer, M., Paik, S. P., Knabbe, J., Sahm, F., Kurz, F. T., Acikgöz, A. A., Herrmannsdörfer, F., Agarwal, A., Bergles, D. E., Chalmers, A., Miletic, H., Turcan, S., Mawrin, C., Hänggi, D., Liu, H.-K., Wick, W., Winkler, F. and Kuner, T. (2019) ‘Glutamatergic synaptic input to glioma cells drives brain tumour progression’, Nature. Macmillan, 573(7775), pp. 532-538. doi: 10.1038/s41586-019-1564-x.   edoc
Brühwiler, L. D., Beeler, P. E., Böni, F., Giger, R., Wiedemeier, P. G., Hersberger, K. E. and Lutters, M. (2019) ‘A RCT evaluating a pragmatic in-hospital service to increase the quality of discharge prescriptions’, International Journal for Quality in Health Care. Oxford University Press, p. mzz043. doi: 10.1093/intqhc/mzz043.   edoc
da Costa, F. A., Mala-Ladova, K., Lee, V., Tous, S., Papastergiou, J., Griffiths, D., Chaumais, M.-C., Hersberger, K. E., Viola, R., Paulino, E., Lobban, T., Neubeck, L., Freedman, B. and Antoniou, S. (2019) ‘Awareness campaigns of atrial fibrillation as an opportunity for early detection by pharmacists: an international cross-sectional study’, Journal of thrombosis and thrombolysis. Springer, pp. 1-12. doi: 10.1007/s11239-019-02000-x.   edoc

2018

Rabbani, S., Fiege, B., Eris, D., Silbermann, M., Jakob, R. P., Navarra, G., Maier, T. and Ernst, B. (2018) ‘Conformational Switch of the Bacterial Adhesin FimH in the Absence of the Regulatory Domain: Engineering a Minimalistic Allosteric System’, Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 293(5), pp. 1835-1849. doi: 10.1074/jbc.M117.802942.   edoc
Ditter, D., Nieto, A., Mahler, H.-C., Roehl, H., Wahl, M., Huwyler, J. and Allmendinger, A. (2018) ‘Evaluation of Glass Delamination Risk in Pharmaceutical 10 mL/10R Vials’, Journal of Pharmaceutical Sciences, 107(2), pp. 624-637. doi: 10.1016/j.xphs.2017.09.016.   edoc
Hersberger, K. E. (2018) ‘Part VI Pharmaceutical Care for Specific Patient Groups ’, The Pharmacist Guide to Implementing Pharmaceutical Care. Springer, pp. 295-296. Available at: https://link.springer.com/content/pdf/bfm%3A978-3-319-92576-9%2F6%2F1.pdf.   edoc
Danton, O., Alexander, L., Hunlun, C., de Beer, D., Hamburger, M. and Joubert, E. (2018) ‘Bitter taste impact and thermal conversion of a naringenin glycoside isolated from Cyclopia genistoides’, Journal of natural products. American Society of Pharmacognosy, 81(12), pp. 2743-2749. doi: 10.1021/acs.jnatprod.8b00710.   edoc
Don, C. G. and Smieško, M. (2018) ‘Out-compute drug side effects: Focus on cytochrome P450 2D6 modeling’, Wiley interdisciplinary reviews; computational molecular science. Wiley, 8(5), p. e1366. doi: 10.1002/wcms.1366.   edoc
Smieško, M., Don, C. G., Meuwly, R., Kucsera, S. and Brüschweiler, B. J. (2018) ‘Large-scale in silico screening of compounds contained in printing inks for food packaging materials’, Toxicology Letters. Elsevier, 295, p. S96. doi: 10.1016/j.toxlet.2018.06.594.   edoc
Wimmersberger, D., Coulibaly, J. T., Schulz, J. D., Puchkov, M., Huwyler, J., N’Gbesso, Y., Hattendorf, J. and Keiser, J. (2018) ‘Efficacy and Safety of Ivermectin Against Trichuris trichiura in Preschool-aged and School-aged Children: A Randomized Controlled Dose-finding Trial’, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 67(8), pp. 1247-1255. doi: 10.1093/cid/ciy246.   edoc
Mohebbi, M., Bararjanian, M., Ebrahimi, S. N., Smiesko, M. and Salehi, P. (2018) ‘Noscapine Derivatives as New Chiral Catalysts in Asymmetric Synthesis: Highly Enantioselective Addition of Diethylzinc to Aldehydes’, SYNTHESIS-STUTTGART. GEORG THIEME VERLAG KG, 50(9), pp. 1841-1848. doi: 10.1055/s-0037-1609224.   edoc
Malagnino, V., Hussner, J., Seibert, I., Stolzenburg, A., Sager, C. P. and Meyer zu Schwabedissen, H. E. (2018) ‘LST-3TM12 is a member of the OATP1B family and a functional transporter’, Biochemical pharmacology, 148, pp. 75-87. doi: 10.1016/j.bcp.2017.12.012.   edoc
Yuan, X., Yang, M., Chen, X., Zhang, X., Sukhadia, S., Musolino, N., Bao, H., Chen, T., Xu, C., Wang, Q., Santoro, S., Ricklin, D., Hu, J., Lin, R., Yang, W., Li, Z., Qin, W., Zhao, A., Scholler, N. and Coukos, G. (2018) ‘Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy’, Cancer immunology, immunotherapy : CII, 67(2), pp. 329-339. doi: 10.1007/s00262-017-2101-0.   edoc
Ditter, D., Mahler, H.-C., Gohlke, L., Nieto, A., Roehl, H., Huwyler, J., Wahl, M. and Allmendinger, A. (2018) ‘Impact of Vial Washing and Depyrogenation on Surface Properties and Delamination Risk of Glass Vials’, Pharmaceutical research, 35(7), p. 146. doi: 10.1007/s11095-018-2421-6.   edoc
Boll, B., Josse, L., Heubach, A., Hochenauer, S., Finkler, C., Huwyler, J. and Koulov, A. V. (2018) ‘Impact of non-ideal analyte behavior on the separation of protein aggregates by asymmetric flow field-flow fractionation’, Journal of Separation Science, 41(13), pp. 2854-2864. doi: 10.1002/jssc.201701457.   edoc
Zihlmann, P., Silbermann, M., Sharpe, T., Jiang, X., Mühlethaler, T., Jakob, R. P., Rabbani, S., Sager, C. P., Frei, P., Pang, L., Maier, T. and Ernst, B. (2018) ‘KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists ’, Chemistry (Weinheim an der Bergstrasse, Germany), 24(49), pp. 1-10. doi: 10.1002/chem.201802599.   edoc
Siegrist, S., Cörek, E., Detampel, P., Sandström, J., Wick, P. and Huwyler, J. (2018) ‘Preclinical hazard evaluation strategy for nanomedicines’, Nanotoxicology, 13(1), pp. 1-27. doi: 10.1080/17435390.2018.1505000.   edoc
Fischer, A., Don, C. G. and Smieško, M. (2018) ‘Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6’, Journal of chemical information and modeling. American Chemical Society, 58(9), pp. 1962-1975. doi: 10.1021/acs.jcim.8b00080.   edoc
Sánchez-Corral, P., Pouw, R. B., López-Trascasa, M. and Józsi, M. (2018) ‘Self-Damage Caused by Dysregulation of the Complement Alternative Pathway: Relevance of the Factor H Protein Family’, Frontiers in immunology, 9, p. 1607. doi: 10.3389/fimmu.2018.01607.   edoc
Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Schultheiss, U. T., Traglia, M., Ahluwalia, T. S., Akiyama, M., Appel, E. V. R., Arking, D. E., Arnold, A., Astrup, A., Beekman, M., Beilby, J. P., Bekaert, S., Boerwinkle, E., Brown, S. J., De Buyzere, M., Campbell, P. J., Ceresini, G., Cerqueira, C., Cucca, F., Deary, I. J., Deelen, J., Eckardt, K.-U., Ekici, A. B., Eriksson, J. G., Ferrrucci, L., Fiers, T., Fiorillo, E., Ford, I., Fox, C. S., Fuchsberger, C., Galesloot, T. E., Gieger, C., Gögele, M., De Grandi, A., Grarup, N., Greiser, K. H., Haljas, K., Hansen, T., Harris, S. E., van Heemst, D., den Heijer, M., Hicks, A. A., den Hollander, W., Homuth, G., Hui, J., Ikram, M. A., Ittermann, T., Jensen, R. A., Jing, J., Jukema, J. W., Kajantie, E., Kamatani, Y., Kasbohm, E., Kaufman, J.-M., Kiemeney, L. A., Kloppenburg, M., Kronenberg, F., Kubo, M., Lahti, J., Lapauw, B., Li, S., Liewald, D. C. M., Lifelines Cohort Study, Lim, E. M., Linneberg, A., Marina, M., Mascalzoni, D., Matsuda, K., Medenwald, D., Meisinger, C., Meulenbelt, I., De Meyer, T., Meyer Zu Schwabedissen, H. E., Mikolajczyk, R., Moed, M., Netea-Maier, R. T., Nolte, I. M., Okada, Y., Pala, M., Pattaro, C., Pedersen, O., Petersmann, A., Porcu, E., Postmus, I., Pramstaller, P. P., Psaty, B. M., Ramos, Y. F. M., Rawal, R., Redmond, P., Richards, J. B., Rietzschel, E. R., Rivadeneira, F., Roef, G., Rotter, J. I., Sala, C. F., Schlessinger, D., Selvin, E., Slagboom, P. E., Soranzo, N., Sørensen, T. I. A., Spector, T. D., Starr, J. M., Stott, D. J., Taes, Y., Taliun, D., Tanaka, T., Thuesen, B., Tiller, D., Toniolo, D., Uitterlinden, A. G., Visser, W. E., Walsh, J. P., Wilson, S. G., Wolffenbuttel, B. H. R., Yang, Q., Zheng, H.-F., Cappola, A., Peeters, R. P., Naitza, S., Völzke, H., Sanna, S., Köttgen, A., Visser, T. J. and Medici, M. (2018) ‘Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation’, Nature communications, 9(1), p. 4455. doi: 10.1038/s41467-018-06356-1.   edoc
Haeuser, C., Goldbach, P., Huwyler, J., Friess, W. and Allmendinger, A. (2018) ‘Imaging Techniques to Characterize Cake Appearance of Freeze-Dried Products’, Journal of pharmaceutical sciences, 107(11), pp. 2810-2822. doi: 10.1016/j.xphs.2018.06.025.   edoc
Wagner-Hattler, L., Schoelkopf, J., Huwyler, J. and Puchkov, M. (2018) ‘Stability investigation of FCC-based tablets for oral suspension with caffeine and oxantel pamoate as model drugs’, Drug development and industrial pharmacy, 45(2), pp. 1-9. doi: 10.1080/03639045.2018.1529784.   edoc
Arnet, I., Greenland, M., Knuiman, M. W., Rankin, J. M., Hung, J., Nedkoff, L., Briffa, T. G. and Sanfilippo, F. M. (2018) ‘Operationalization and validation of a novel method to calculate adherence to polypharmacy with refill data from the Australian pharmaceutical benefits scheme (PBS) database’, Clinical Epidemiology, 10, pp. 1181-1194. doi: 10.2147/CLEP.S153496.   edoc
Metaxas, C., Albert, V., Stahl, M., Hersberger, K. E. and Arnet, I. (2018) ‘Development and validation of a questionnaire to self-assess patient knowledge of direct oral anticoagulants (KODOA-test)’, Drug Healthcare and Patient Safety, 10, pp. 69-77. doi: 10.2147/DHPS.S152954.   edoc
Arnet, I., Holden, M., Antoniou, S. and iPact group (2018) ‘Evaluation of a prompt card for community pharmacists performing consultations with patients on anticoagulation - lessons learned’, Pharmacy practice, 16(3), p. 1244. doi: 10.18549/PharmPract.2018.03.1244.   edoc
Arnet, I., Gudka, S., Salter, S., Hersberger, K. E. and Clifford, R. (2018) ‘Readiness of pharmacists and consumers for pharmacy-based chlamydia screening in Australia and Switzerland’, Sexual and Reproductive Healthcare, 16, pp. 138-153. doi: 10.1016/j.srhc.2018.03.006.   edoc
Porta, F., Ehrsam, D., Lengerke, C. and Meyer Zu Schwabedissen, H. E. (2018) ‘Synthesis and characterization of a PDMS-PMOXA based polymersomes sensitive to MMP-9 for application in breast cancer’, Molecular pharmaceutics, 15((11), pp. 4884-4897. doi: 10.1021/acs.molpharmaceut.8b00521.   edoc
Wahl, J. and Smieško, M. (2018) ‘Thermodynamic Insight into Effects of Water Displacement and Rearrangement upon Ligand Modification using Molecular Dynamics Simulations’, ChemMedChem, 13(13), pp. 1325-1335. doi: 10.1002/cmdc.201800093.   edoc
Meyer-Massetti, C., Hofstetter, V., Hedinger-Grogg, B., Meier, C. R. and Guglielmo, B. J. (2018) ‘Medication-related problems during transfer from hospital to home care: baseline data from Switzerland’, International journal of clinical pharmacy, 40(6), pp. 1614-1620. doi: 10.1007/s11096-018-0728-3.   edoc
Imfeld, P., Bodmer, M., Jick, S. S. and Meier, C. R. (2018) ‘Authors’ Reply to Katsuhiro Toda’s Comment on “Proton Pump Inhibitor Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case-Control Analysis”’, Drug safety, 41(12), p. 1413. doi: 10.1007/s40264-018-0741-4.   edoc
Imfeld, P., Bodmer, M., Jick, S. S. and Meier, C. R. (2018) ‘Proton Pump Inhibitor Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case-Control Analysis’, Drug safety, 41(12), pp. 1387-1396. doi: 10.1007/s40264-018-0704-9.   edoc
Frey, N., Bodmer, M., Bircher, A., Jick, S. S., Meier, C. R. and Spoendlin, J. (2018) ‘Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Association with Commonly Prescribed Drugs in Outpatient Care Other than Anti-Epileptic Drugs and Antibiotics: A Population-Based Case-Control Study’, Drug safety, 42(1), p. nn. doi: 10.1007/s40264-018-0711-x.   edoc
Mueller, A. M., Meier, C. R., Jick, S. S. and Schneider, C. (2018) ‘The Potential of Glycemic Control and Body Weight Change as Early Markers for Pancreatic Cancer in Patients With Long-standing Diabetes Mellitus: A Case-Control Study’, Pancreas, 47(7), pp. 807-815. doi: 10.1097/MPA.0000000000001085.   edoc
Wilson, J. C., Sarsour, K., Gale, S., Pethö-Schramm, A., Jick, S. S. and Meier, C. R. (2018) ‘ Incidence and Risk of Glucocorticoid-Associated Adverse Effects in Patients With Rheumatoid Arthritis ’, Arthritis Care and Research. Wiley, 71(4), pp. 498-511. doi: 10.1002/acr.23611.   edoc
Burkard, T., Hügle, T., Layton, J. B., Glynn, R. J., Bloechliger, M., Frey, N., Jick, S. S., Meier, C. R. and Spoendlin, J. (2018) ‘Risk of Incident Osteoarthritis of the Hand in Statin Initiators: A Sequential Cohort Study’, Arthritis Care and Research. Wiley, 70(12), pp. 1795-1805. doi: 10.1002/acr.23616.   edoc
Frey, N., Bodmer, M., Bircher, A., Rüegg, S., Jick, S. S., Meier, C. R. and Spoendlin, J. (2018) ‘Response: The risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptic drugs: Comment on data sparsity’, Epilepsia, 59(5), pp. 1084-1085. doi: 10.1111/epi.14063.   edoc
Layton, J. B., Li, D., Meier, C. R., Sharpless, J. L., Stürmer, T. and Brookhart, M. A. (2018) ‘Injection testosterone and adverse cardiovascular events: A case-crossover analysis’, Clinical endocrinology, 88(5), pp. 719-727. doi: 10.1111/cen.13574.   edoc
Frey, N., Bircher, A., Bodmer, M., Jick, S. S., Meier, C. R. and Spoendlin, J. (2018) ‘Antibiotic Drug Use and the Risk of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Population-Based Case-Control Study’, Journal of Investigative Dermatology. Elsevier, 138(5), pp. 1207-1209. doi: 10.1016/j.jid.2017.12.015.   edoc
Gruntz, K., Bloechliger, M., Becker, C., Jick, S. S., Fuhr, P., Meier, C. R. and Rüegg, S. (2018) ‘Parkinson disease and the risk of epileptic seizures’, Annals of Neurology. Wiley, 83(2), pp. 363-374. doi: 10.1002/ana.25157.   edoc
Schneider, C., Bodmer, M., Jick, S. S. and Meier, C. R. (2018) ‘Colorectal cancer and markers of anemia’, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 27(6), pp. 530-538. doi: 10.1097/CEJ.0000000000000397.   edoc
Berger, B., Bachmann, F., Duthaler, U., Krähenbühl, S. and Haschke, M. (2018) ‘Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug’, Frontiers in pharmacology, 9, p. 774. doi: 10.3389/fphar.2018.00774.   edoc
Grünig, D., Duthaler, U. and Krähenbühl, S. (2018) ‘Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells’, Frontiers in pharmacology, 9, p. 257. doi: 10.3389/fphar.2018.00257.   edoc
Grünig, D., Felser, A., Duthaler, U., Bouitbir, J. and Krähenbühl, S. (2018) ‘Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells’, Toxicological sciences : an official journal of the Society of Toxicology, 164(2), pp. 477-488. doi: 10.1093/toxsci/kfy101.   edoc

2017

Widmer, N., Schumacher, L., Meister, T., Krähenbühl, J.-M., Mühlebach, S. and Bonnabry, P. (2017) ‘Notfall- und Katastrophenpharmazie: Neues Schweizer Fachzentrum’, PharmaJournal. Schweizer Apothekerzeitung. PharmaSuisse, 155(15), pp. 14-17.   edoc | Open Access
Brueckner, D., Krähenbühl, S., Zuber, U., Bonkat, G. and Braissant, O. (2017) ‘An alternative sterility assessment for parenteral drug products using isothermal microcalorimetry’, Journal of Applied Microbiology, 123(3), pp. 773-779. doi: 10.1111/jam.13520.   edoc
Krähenbühl, S. and Pichler, W. J. (2017) ‘Medikamentöse Hepatopathien - Drug-induced liver injury’, Therapeutische Umschau. Hogrefe, 74(3), pp. 123-130. doi: 10.1024/0040-5930/a000895.   edoc
Paech, F., Bouitbir, J. and Krähenbühl, S. (2017) ‘Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis’, Frontiers in pharmacology. Frontiers Media, 8, p. 367. doi: 10.3389/fphar.2017.00367.   edoc
Barda, B., Sayasone, S., Phongluxa, K., Xayavong, S., Keoduangsy, K., Odermatt, P., Puchkov, M., Huwyler, J., Hattendorf, J. and Keiser, J. (2017) ‘Efficacy of Moxidectin Versus Ivermectin Against Strongyloides stercoralis Infections: A Randomized, Controlled Noninferiority Trial’, Clinical Infectious Diseases. Oxford University Press, 65(2), pp. 276-281. doi: 10.1093/cid/cix278.   edoc
Krähenbühl, S. (2017) ‘Importance of the skeletal muscle carnitine stores in fuel selection’, The Journal of Physiology. Wiley, 595(17), pp. 5727-5728. doi: 10.1113/JP274755.   edoc
Blaser, L., Hassna, H., Hofmann, S., Holbro, A., Haschke, M., Rätz Bravo, A., Zeller, A., Krähenbühl, S. and Taegtmeyer, A. (2017) ‘Leucopenia associated with metamizole: a case-control study’, Swiss medical weekly. EMH Swiss Medical Publishers, 147, p. w14438. doi: 10.4414/smw.2017.14438.   edoc
Brueckner, D., Solokhina, A., Krähenbühl, S. and Braissant, O. (2017) ‘A combined application of tunable diode laser absorption spectroscopy and isothermal micro-calorimetry for calorespirometric analysis’, Journal of Microbiological Methods. Elsevier, 139, pp. 210-214. doi: 10.1016/j.mimet.2017.06.012.   edoc
Drago, S., Imboden, R., Schlatter, P., Buylaert, M., Krähenbühl, S. and Drewe, J. (2017) ‘Pharmacokinetics of Transdermal Etofenamate and Diclofenac in Healthy Volunteers’, Basic and Clinical Pharmacology and Toxicology. Wiley, 121(5), pp. 423-429. doi: 10.1111/bcpt.12818.   edoc
Grünig, D., Felser, A., Bouitbir, J. and Krähenbühl, S. (2017) ‘The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells’, Toxicology in Vitro. Elsevier, 42, pp. 337-347. doi: 10.1016/j.tiv.2017.05.013.   edoc
Paech, F., Messner, S., Spickermann, J., Wind, M., Schmitt-Hoffmann, A.-H., Witschi, A. T., Howell, B. A., Church, R. J., Woodhead, J., Engelhardt, M., Krähenbühl, S. and Maurer, M. (2017) ‘Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072’, Archives of Toxicology. Springer, 91(11), pp. 3647-3662. doi: 10.1007/s00204-017-1994-x.   edoc
Haegler, P., Joerin, L., Krähenbühl, S. and Bouitbir, J. (2017) ‘Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents’, Toxicological sciences. Oxford University Press, 157(1), pp. 183-195. doi: 10.1093/toxsci/kfx029.   edoc
Brueckner, D., Roesti, D., Zuber, U., Sacher, M., Duncan, D., Krähenbühl, S. and Braissant, O. (2017) ‘Tunable diode laser absorption spectroscopy as method of choice for non-invasive and automated detection of microbial growth in media fills’, Talanta. Elsevier, 167, pp. 21-29. doi: 10.1016/j.talanta.2017.01.088.   edoc
Randazzo, G. M., Tonoli, D., Strajhar, P., Xenarios, I., Odermatt, A., Boccard, J. and Rudaz, S. (2017) ‘Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study’, Journal of Chromatography B. Elsevier, 1071, pp. 11-18. doi: 10.1016/j.jchromb.2017.04.032.   edoc
Jiménez-Canino, R., Lorenzo-Díaz, F., Odermatt, A., Bailey, M. A., Livingstone, D. E. W., Jaisser, F., Farman, N. and Alvarez de la Rosa, D. (2017) ‘11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation’, Endocrinology. Oxford University Press, 158(11), pp. 4047-4063. doi: 10.1210/en.2017-00440.   edoc
Brecht, K., Riebel, V., Couttet, P., Paech, F., Wolf, A., Chibout, S.-D., Pognan, F., Krähenbühl, S. and Uteng, M. (2017) ‘Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin’, Toxicology in Vitro. Elsevier, 40, pp. 55-65. doi: 10.1016/j.tiv.2016.12.001.   edoc
Aeberhard , C. and Mühlebach, S. (2017) ‘Parenterale Ernährung - Grundlagen und Durchführung (Parenteral nutrition - basics and good practice)’, Aktuelle Ernährungsmedizin, 42(1), pp. 53-76. doi: 10.1055/s-0042-121786.   edoc
Astier, A., Barton Pai, A., Bissig, M., Crommelin, D. J. A., Flühmann, B., Hecq, J.-D., Knoeff, J., Lipp, H.-P., Morell-Baladrón, A. and Mühlebach, S. (2017) ‘How to select a nanosimilar’, Annals of the New York Academy of Sciences, 1407(1), pp. 50-62. doi: 10.1111/nyas.13382.   edoc
Hussaarts, L., Mühlebach, S., Shah, V. P., McNeil, S., Borchard, G., Flühmann, B., Weinstein, V., Neervannan, S., Griffiths, E., Jiang, W., Wolff-Holz, E., Crommelin, D. J. A. and de Vlieger, J. S. B. (2017) ‘Equivalence of complex drug products: advances in and challenges for current regulatory frameworks’, Annals of the New York Academy of Sciences, 1407(1), pp. 39-49. doi: 10.1111/nyas.13347.   edoc
Aeberhard, C., Steuer, C., Saxer, C., Huber, A., Stanga, Z. and Mühlebach, S. (2017) ‘Physicochemical stability and compatibility testing of levetiracetam in all-in-one parenteral nutrition admixtures in daily practice’, European journal of pharmaceutical sciences, 96, pp. 449-455. doi: 10.1016/j.ejps.2016.10.015.   edoc
Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Fearon, K., Hütterer, E., Isenring, E., Kaasa, S., Krznaric, Z., Laird, B., Larsson, M., Laviano, A., Mühlebach, S., Muscaritoli, M., Oldervoll, L., Ravasco, P., Solheim, T., Strasser, F., de van der Schueren, M. and Preiser, J.-C. (2017) ‘ESPEN guidelines on nutrition in cancer patients’, Clinical nutrition, 36(1), pp. 11-48. doi: 10.1016/j.clnu.2016.07.015.   edoc
Engeli, R. T., Tsachaki, M., Hassan, H. A., Sager, C. P., Essawi, M. L., Gad, Y. Z., Kamel, A. K., Mazen, I. and Odermatt, A. (2017) ‘Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients’, The journal of sexual medicine, 14(9), pp. 1165-1174. doi: 10.1016/j.jsxm.2017.07.006.   edoc
Knöpfel, T., Pastor-Arroyo, E. M., Schnitzbauer, U., Kratschmar, D. V., Odermatt, A., Pellegrini, G., Hernando, N. and Wagner, C. A. (2017) ‘The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction’, Scientific reports, 7(1), p. 11018. doi: 10.1038/s41598-017-10390-2.   edoc
Dolder, P. C., Strajhar, P., Vizeli, P., Hammann, F., Odermatt, A. and Liechti, M. E. (2017) ‘Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects’, Frontiers in pharmacology, 8, p. 617. doi: 10.3389/fphar.2017.00617.   edoc
van Beek, A. E., Pouw, R. B., Brouwer, M. C., van Mierlo, G., Geissler, J., Ooijevaar-de Heer, P., de Boer, M., van Leeuwen, K., Rispens, T., Wouters, D. and Kuijpers, T. W. (2017) ‘Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma’, Frontiers in Immunology. Frontiers Media, 8, p. 1328. doi: 10.3389/fimmu.2017.01328.   edoc
Engeli, R. T., Rohrer, S. R., Vuorinen, A., Herdlinger, S., Kaserer, T., Leugger, S., Schuster, D. and Odermatt, A. (2017) ‘Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases’, International Journal of Molecular Sciences, 18(9), pp. 1-13. doi: 10.3390/ijms18092007.   edoc | Open Access
Aghagolzadeh, P., Radpour, R., Bachtler, M., van Goor, H., Smith, E. R., Lister, A., Odermatt, A., Feelisch, M. and Pasch, A. (2017) ‘Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation’, Atherosclerosis, 265, pp. 78-86. doi: 10.1016/j.atherosclerosis.2017.08.012.   edoc
Morgan, R. A., Beck, K. R., Nixon, M., Homer, N. Z. M., Crawford, A. A., Melchers, D., Houtman, R., Meijer, O. C., Stomby, A., Anderson, A. J., Upreti, R., Stimson, R. H., Olsson, T., Michoel, T., Cohain, A., Ruusalepp, A., Schadt, E. E., Björkegren, J. L. M., Andrew, R., Kenyon, C. J., Hadoke, P. W. F., Odermatt, A., Keen, J. A. and Walker, B. R. (2017) ‘Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity’, Scientific Reports, 7(1), p. 10633. doi: 10.1038/s41598-017-10410-1.   edoc | Open Access
Alesutan, I., Voelkl, J., Feger, M., Kratschmar, D. V., Castor, T., Mia, S., Sacherer, M., Viereck, R., Borst, O., Leibrock, C., Gawaz, M., Kuro-O, M., Pilz, S., Tomaschitz, A., Odermatt, A., Pieske, B., Wagner, C. A. and Lang, F. (2017) ‘Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells’, Scientific Reports, 7(1), p. 2059. doi: 10.1038/s41598-017-01882-2.   edoc | Open Access
Monzel, J. V., Budde, T., Meyer zu Schwabedissen, H. E., Schwebe, M., Bien-Möller, S., Lütjohann, D., Kroemer, H. K., Jedlitschky, G. and Grube, M. (2017) ‘Doxorubicin enhance oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters’, Biochemical pharmacology, 144, pp. 108-119. doi: 10.1016/j.bcp.2017.08.008.   edoc
Flesch, D., Cheung, S.-Y., Schmidt, J., Gabler, M., Heitel, P., Kramer, J., Kaiser, A., Hartmann, M., Lindner, M., Lüddens-Dämgen, K., Heering, J., Lamers, C., Lüddens, H., Wurglics, M., Proschak, E., Schubert-Zsilavecz, M. and Merk, D. (2017) ‘Nonacidic Farnesoid X Receptor Modulators’, Journal of Medicinal Chemistry, 60(16), pp. 7199-7205. doi: 10.1021/acs.jmedchem.7b00903.   edoc
Cramer, J. and Klebe, G. (2017) ‘An Allyl Protection and Improved Purification Strategy Enables the Synthesis of Functionalized Phosphonamidate Peptides’, Synthesis. GEORG THIEME VERLAG KG, 49(8), pp. 1857-1866. doi: 10.1055/s-0036-1588393.   edoc
Cramer, J., Krimmer, S. G., Fridh, V., Wulsdorf, T., Karlsson, R., Heine, A. and Klebe, G. (2017) ‘Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin’, ACS Chemical Biology, 12(1), pp. 225-233. doi: 10.1021/acschembio.6b00979.   edoc
Cramer, J., Schiebel, J., Wulsdorf, T., Grohe, K., Najbauer, E. E., Ehrmann, F. R., Radeva, N., Zitzer, N., Linne, U., Linser, R., Heine, A. and Klebe, G. (2017) ‘A False-Positive Screening Hit in Fragment-Based Lead Discovery: Watch out for the Red Herring’, Angewandte Chemie (International Edition), 56(7), pp. 1908-1913. doi: 10.1002/anie.201609824.   edoc
Cramer, J., Krimmer, S. G., Heine, A. and Klebe, G. (2017) ‘Paying the Price of Desolvation in Solvent-Exposed Protein Pockets: Impact of Distal Solubilizing Groups on Affinity and Binding Thermodynamics in a Series of Thermolysin Inhibitors’, Journal of Medicinal Chemistry, 60(13), pp. 5791-5799. doi: 10.1021/acs.jmedchem.7b00490.   edoc
Krimmer, S. G., Cramer, J., Schiebel, J., Heine, A. and Klebe, G. (2017) ‘How Nothing Boosts Affinity: Hydrophobic Ligand Binding to the Virtually Vacated S1′ Pocket of Thermolysin’, Journal of the American Chemical Society, 139(30), pp. 10419-10431. doi: 10.1021/jacs.7b05028.   edoc
Zhang, P., Hevey, R. and Ling, C.-C. (2017) ‘Total Synthesis of β-d-ido-Heptopyranosides Related to Capsular Polysaccharides of Campylobacter jejuni HS:4’, The Journal of Organic Chemistry, 82(18), pp. 9662-9674. doi: 10.1021/acs.joc.7b01752.   edoc
Hevey, R. and Ling, C.-C. (2017) ‘Studies on the 6-homologation of β-D-idopyranosides’, Carbohydrate Research, 445, pp. 65-74. doi: 10.1016/j.carres.2017.04.007.   edoc
Prestin, K., Olbert, M., Hussner, J., Völzke, H. and Meyer zu Schwabedissen, H. E. (2017) ‘Functional assessment of genetic variants located in the promoter of SHP1 (NR0B2)’, Pharmacogenetics and Genomics, 27(11), pp. 410-415. doi: 10.1097/FPC.0000000000000310.   edoc
Legeza, B., Marcolongo, P., Gamberucci, A., Varga, V., Bánhegyi, G., Benedetti, A. and Odermatt, A. (2017) ‘Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome’, Nutrients, 9(5), p. E426. doi: 10.3390/nu9050426.   edoc | Open Access

2016

Moradi-Afrapoli, F., Oufir, M., Walter, F. R., Deli, M. A., Smieško, M., Zabela, V., Butterweck, V. and Hamburger, M. (2016) ‘Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro BBB and intestinal drug permeability studies’, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 264-274. doi: 10.1016/j.jpba.2016.05.039.   edoc
Jähne, E. A., Sampath, C., Butterweck, V., Hamburger, M. and Oufir, M. (2016) ‘Development and full validation of an UPLC-MS/MS method for the quantification of indirubin in rat plasma’, Journal of Pharmaceutical and Biomedical Analysis. Elsevier, 128, pp. 247-252. doi: 10.1016/j.jpba.2016.05.018.   edoc
Kettiger, H., Québatte, G., Perrone, B. and Huwyler, J. (2016) ‘Interactions between silica nanoparticles and phospholipid membranes’, Biochimica et biophysica acta. Elsevier, 1858(9), pp. 2163-2170. doi: 10.1016/j.bbamem.2016.06.023.   edoc
Hussner, J., Sünwoldt, J., Seibert, I., Gliesche, D. G. and Meyer zu Schwabedissen, H. E. (2016) ‘Pimecrolimus increases the expression of interferon-inducible genes that modulate human coronary artery cells proliferation’, European Journal of Pharmacology. Elsevier, 784, pp. 137-146. doi: 10.1016/j.ejphar.2016.05.020.   edoc
Buck, J., Huwyler, J., Kühl, P. and Dischinger, A. (2016) ‘Pediatric Dispersible Tablets: a Modular Approach for Rapid Prototyping’, Pharmaceutical research. Plenum Press, 33(8), pp. 2043-2055. doi: 10.1007/s11095-016-1946-9.   edoc
Preisig, D., Roth, R., Tognola, S., Varum, F. J. O., Bravo, R., Cetinkaya, Y., Huwyler, J. and Puchkov, M. (2016) ‘Mucoadhesive microparticles for local treatment of gastrointestinal diseases’, European journal of pharmaceutics and biopharmaceutics. Elsevier, 105, pp. 156-165. doi: 10.1016/j.ejpb.2016.06.009.   edoc
Gliesche, D. G., Hussner, J., Witzigmann, D., Porta, F., Glatter, T., Schmidt, A., Huwyler, J. and Meyer Zu Schwabedissen, H. E. (2016) ‘Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries’, Molecular Pharmaceutics. American Chemical Society, 13(7), pp. 2290-2300. doi: 10.1021/acs.molpharmaceut.6b00033.   edoc
Bischoff, T., Vogl, C. R., Ivemeyer, S., Klarer, F., Meier, B., Hamburger, M. and Walkenhorst, M. (2016) ‘Plant and natural product based household remedies manufactured and used by farmers of six central Swiss cantons to treat livestock’, Livestock science. Elsevier, 189, pp. 110-125. doi: 10.1016/j.livsci.2016.05.003.   edoc
Hu, Z., Wahl, J., Hamburger, M. and Vedani, A. (2016) ‘Molecular mechanisms of endocrine and metabolic disruption: An in silico study on antitrypanosomal natural products and some derivatives’, Toxicology Letters. Elsevier, 252, pp. 29-41. doi: 10.1016/j.toxlet.2016.04.013.   edoc
Eigenmann, D. E., Dürig, C., Jähne, E. A., Smieško, M., Culot, M., Gosselet, F., Cecchelli, R., Cederberg Helms, H. C., Brodin, B., Wimmer, L., Mihovilovic, M. D., Hamburger, M. and Oufir, M. (2016) ‘In vitro blood-brain barrier permeability predictions of piperine analogues with GABAA receptor modulating properties’, European Journal of Pharmaceutics and Biopharmaceutics. Elsevier, 103, pp. 118-126. doi: 10.1016/j.ejpb.2016.03.029.   edoc
Witzigmann, D., Quagliata, L., Schenk, S. H., Quintavalle, C., Terracciano, L. M. and Huwyler, J. (2016) ‘Variable asialoglycoprotein-receptor 1 expression in liver disease: Implications for therapeutic intervention’, Hepatology research . Blackwell, 46(7), pp. 686-696. doi: 10.1111/hepr.12599.   edoc
Eberle, V. A., Häring, A., Schoelkopf, J., Gane, P. A. C., Huwyler, J. and Puchkov, M. (2016) ‘In silico and in vitro methods to optimize the performance of experimental gastroretentive floating mini-tablets’, Drug development and industrial pharmacy. Informa Healthcare, 42(5), pp. 808-817. doi: 10.3109/03639045.2015.1078350.   edoc
Canonica, J., Sergi, C., Maillard, M., Klusonova, P., Odermatt, A., Koesters, R., Loffing-Cueni, D., Loffing, J., Rossier, B., Frateschi, S. and Hummler, E. (2016) ‘Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype’, Pflügers Archiv : European journal of physiology. Springer, 468(5), pp. 895-908. doi: 10.1007/s00424-015-1785-2.   edoc
Mani, O., Nashev, L. G., Livelo, C., Baker, M. E. and Odermatt, A. (2016) ‘Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone’, The Journal of steroid biochemistry and molecular biology. Elsevier, 159, pp. 31-40. doi: 10.1016/j.jsbmb.2016.02.017.   edoc
Riede, J., Poller, B., Umehara, K.- ichi, Huwyler, J. and Camenisch, G. (2016) ‘New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data’, European journal of pharmaceutical sciences. Elsevier, 86, pp. 96-102. doi: 10.1016/j.ejps.2016.02.022.   edoc
Odermatt, A., Strajhar, P. and Engeli, R. T. (2016) ‘Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools’, The Journal of steroid biochemistry and molecular biology. Elsevier, 158, pp. 9-21. doi: 10.1016/j.jsbmb.2016.01.009.   edoc
Grabe, H. J., Wittfeld, K., Van der Auwera, S., Janowitz, D., Hegenscheid, K., Habes, M., Homuth, G., Barnow, S., John, U., Nauck, M., Völzke, H., Meyer zu Schwabedissen, H. E., Freyberger, H. J. and Hosten, N. (2016) ‘Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample’, Human brain mapping. Wiley-Liss, 37(4), pp. 1602-1613. doi: 10.1002/hbm.23123.   edoc
Bloechliger, M., Ceschi, A., Rüegg, S., Kupferschmidt, H., Krähenbühl, S., Jick, S. S., Meier, C. R. and Bodmer, M. (2016) ‘Risk of Seizures Associated with Antidepressant Use in Patients with Depressive Disorder: Follow-up Study with a Nested Case-Control Analysis Using the Clinical Practice Research Datalink’, Drug Safety . Springer, 39(4), pp. 307-321. doi: 10.1007/s40264-015-0363-z.   edoc
Seliger, C., Meier, C. R., Jick, S. S., Uhl, M., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) ‘Use of cardiac glycosides and risk of glioma’, Journal of Neuro-Oncology . Springer Science+Business Media B.V., 127(2), pp. 321-328. doi: 10.1007/s11060-015-2036-2.   edoc
Ramming, T., Kanemura, S., Okumura, M., Inaba, K. and Appenzeller-Herzog, C. (2016) ‘Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover’, Redox biology. Elsevier, 7, pp. 14-20. doi: 10.1016/j.redox.2015.11.004.   edoc
Strajhar, P., Schmid, Y., Liakoni, E., Dolder, P. C., Rentsch, K. M., Kratschmar, D. V., Odermatt, A. and Liechti, M. E. (2016) ‘Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects’, Journal of Neuroendocrinology. Wiley, 28(3), p. 12374. doi: 10.1111/jne.12374.   edoc | Open Access
Coqueiro, A., Choi, Y. H., Verpoorte, R., Sankar Gupta, K. B. S., De Mieri, M., Hamburger, M., Marx Young, M. C., Stapleton, P., Gibbons, S. and da Silva Bolzani, V. (2016) ‘Anti-staphylococcal prenylated acylphoroglucinol and xanthones from Kielmeyera variabilis (Clusiaceae)’, Journal of natural products. American Society of Pharmacognosy, 79(3), pp. 470-476. doi: 10.1021/acs.jnatprod.5b00858.   edoc
Eigenmann, D. E., Jähne, E. A., Smiesko, M., Hamburger, M. and Oufir, M. (2016) ‘Validation of an immortalized human (hBMEC) in vitro blood-brain barrier model’, Analytical and Bioanalytical Chemistry. Springer, 408(8), pp. 2095-2107. doi: 10.1007/s00216-016-9313-6.   edoc
Seliger, C., Ricci, C., Meier, C. R., Bodmer, M., Jick, S. S., Bogdahn, U., Hau, P. and Leitzmann, M. F. (2016) ‘Diabetes, use of antidiabetic drugs, and the risk of glioma’, Neuro-Oncology. Oxford University Press, 18(3), pp. 340-349. doi: 10.1093/neuonc/nov100.   edoc | Open Access
Bornand, D., Toovey, S., Jick, S. S. and Meier, C. R. (2016) ‘The risk of new onset depression in association with influenza - a population-based observational study’, Brain, Behavior and Immunity . Elsevier, 53, pp. 131-137. doi: 10.1016/j.bbi.2015.12.005.   edoc
Requena, G., Huerta, C., Gardarsdottir, H., Logie, J., González-González, R., Abbing-Karahagopian, V., Miret, M., Schneider, C., Souverein, P. C., Webb, D., Afonso, A., Boudiaf, N., Martin, E., Oliva, B., Alvarez, A., De Groot, M. C. H., Bate, A., Johansson, S., Schlienger, R., Reynolds, R., Klungel, O. H. and de Abajo, F. J. (2016) ‘Hip/femur fractures associated with the use of benzodiazepines (anxiolytics, hypnotics and related drugs): a methodological approach to assess consistencies across databases from the PROTECT-EU project’, Pharmacoepidemiology and drug safety. Wiley, 25(1), pp. 66-78. doi: 10.1002/pds.3816.   edoc
Huerta, C., Abbing-Karahagopian, V., Requena, G., Oliva, B., Alvarez, Y., Gardarsdottir, H., Miret, M., Schneider, C., Gil, M., Souverein, P. C., De Bruin, M. L., Slattery, J., De Groot, M. C. H., Hesse, U., Rottenkolber, M., Schmiedl, S., Montero, D., Bate, A., Ruigomez, A., García-Rodríguez, L. A., Johansson, S., de Vries, F., Schlienger, R. G., Reynolds, R. F., Klungel, O. H. and de Abajo, F. J. (2016) ‘Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project’, Pharmacoepidemiology and drug safety. John Wiley, 25(1), pp. 56-65. doi: 10.1002/pds.3825.   edoc
Spoendlin, J., Karatas, G., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) ‘Rosacea in Patients with Ulcerative Colitis and Crohn’s Disease: a Population-based Case-control Study’, Inflammatory Bowel Diseases. Lippincott Williams & Wilkins, 22(3), pp. 680-687. doi: 10.1097/MIB.0000000000000644.   edoc
Corradi, E., De Mieri, M., Cadisch, L., Abbet, C., Hamburger, M. and Potterat, O. (2016) ‘New Acylated Flavonol Glycosides and a Phenolic Profile of Pritzelago alpina, a Forgotten Edible Alpine Plant ’, Chemistry & Biodiversity. Helvetica Chimica Acta, 13(2), pp. 188-197. doi: 10.1002/cbdv.201500353.   edoc
Ríos Quiroz, A., Lamerz, J., De Cunha, T., Boillon, A., Adler, M., Finkler, C., Huwyler, J., Schmidt, R., Mahler, H.-C. and Koulov, A. V. (2016) ‘Factors Governing the Precision of Subvisible Particle Measurement Methods - A Case Study with a Low-Concentration Therapeutic Protein Product in a Prefilled Syringe’, Pharmaceutical research. Springer, 33(2), pp. 450-461. doi: 10.1007/s11095-015-1801-4.   edoc
Wilson, J. C., Furlano, R. I., Jick, S. S. and Meier, C. R. (2016) ‘Inflammatory Bowel Disease and the Risk of Autoimmune Diseases’, Journal of Crohn’s and Colitis. Elsevier, 10(2), pp. 186-193. doi: 10.1093/ecco-jcc/jjv193.   edoc
Mathaes, R., Mahler, H.-C., Buettiker, J.-P., Roehl, H., Lam, P., Brown, H., Luemkemann, J., Adler, M., Huwyler, J., Streubel, A. and Mohl, S. (2016) ‘The pharmaceutical vial capping process; Container closure systems, capping equipment, regulatory framework, and seal quality tests’, European journal of pharmaceutics and biopharmaceutics. Elsevier, 99, pp. 54-64. doi: 10.1016/j.ejpb.2015.11.016.   edoc
Rizner, T. L., Sasano, H., Choi, M. H., Odermatt, A. and Adamski, J. (2016) ‘Recommendations for description and validation for antibodies for research use’, The journal of steroid biochemistry and molecular biology. Pergamon, 156, pp. 40-42. doi: 10.1016/j.jsbmb.2015.11.021.   edoc
Krimmer, S. G., Cramer, J., Betz, M., Fridh, V., Karlsson, R., Heine, A. and Klebe, G. (2016) ‘Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound Ligands’, Journal of medicinal chemistry, 59(23), pp. 10530-10548. doi: 10.1021/acs.jmedchem.6b00998.   edoc
Lamers, C., Merk, D., Gabler, M., Flesch, D., Kaiser, A. and Schubert-Zsilavecz, M. (2016) ‘SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound’, Future medicinal chemistry, 8(2), pp. 133-148. doi: 10.4155/fmc.15.178.   edoc
Blöcher, R., Lamers, C., Wittmann, S. K., Merk, D., Hartmann, M., Weizel, L., Diehl, O., Brüggerhoff, A., Boß, M., Kaiser, A., Schader, T., Göbel, T., Grundmann, M., Angioni, C., Heering, J., Geisslinger, G., Wurglics, M., Kostenis, E., Brüne, B., Steinhilber, D., Schubert-Zsilavecz, M., Kahnt, A. S. and Proschak, E. (2016) ‘N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators’, Journal of medicinal chemistry, 59(1), pp. 61-81. doi: 10.1021/acs.jmedchem.5b01239.   edoc
Kanemura, S., Okumura, M., Yutani, K., Ramming, T., Hikima, T., Appenzeller-Herzog, C., Akiyama, S. and Inaba, K. (2016) ‘Human ER Oxidoreductin-1α (Ero1α) Undergoes Dual Regulation through Complementary Redox Interactions with Protein-Disulfide Isomerase’, The Journal of biological chemistry, 291(46), pp. 23952-23964. doi: 10.1074/jbc.M116.735662.   edoc
Appenzeller-Herzog, C., Bánhegyi, G., Bogeski, I., Davies, K. J. A., Delaunay-Moisan, A., Forman, H. J., Görlach, A., Kietzmann, T., Laurindo, F., Margittai, E., Meyer, A. J., Riemer, J., Rützler, M., Simmen, T., Sitia, R., Toledano, M. B. and Touw, I. P. (2016) ‘Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish’, Free radical biology & medicine, 94, pp. 157-160. doi: 10.1016/j.freeradbiomed.2016.02.030.   edoc
Appenzeller-Herzog, C. and Simmen, T. (2016) ‘ER-luminal thiol/selenol-mediated regulation of Ca2+ signalling’, Biochemical Society transactions, 44(2), pp. 452-459. doi: 10.1042/BST20150233.   edoc
Philipp, E., Braitsch, M., Bichsel, T. and Mühlebach, S. (2016) ‘Diluting ferric carboxymaltose in sodium chloride infusion solution (0.9% w/v) in polypropylene bottles and bags: effects on chemical stability’, European journal of hospital pharmacy : science and practice [2047-9956], 23(1), pp. 22-27. doi: 10.1136/ejhpharm-2015-000697.   edoc

2015

Kettiger, H., Karaman, D. S., Schiesser, L., Rosenholm, J. M. and Huwyler, J. (2015) ‘Comparative safety evaluation of silica-based particles’, Toxicology in vitro. Elsevier, 30(1), pp. 355-363. doi: 10.1016/j.tiv.2015.09.030.   edoc
Moghadam, S. E., Ebrahimi, S. N., Gafner, F., Ochola, J. B., Marubu, R. M., Lwande, W., Frei Haller, B., Salehi, P. and Hamburger, M. (2015) ‘Metabolite profiling for caffeic acid oligomers in Satureja biflora’, Industrial Crops and Products. Elsevier, 76, pp. 892-899. doi: 10.1016/j.indcrop.2015.07.059.   edoc
Arnet, I., Altermatt, M., Roggo, Y. and Schnetzler, G. (2015) ‘Pharmaceutical quality of eight generics of ceftriaxone preparation for injection in Eastern Asia’, Journal of chemotherapy . Taylor & Francis Group, 27(6), pp. 337-342. doi: 10.1179/1973947814Y.0000000208.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) ‘Association of hormone therapy and incident gout: population-based case-control study’, Menopause. Lippincott, 22(12), pp. 1335-1342. doi: 10.1097/GME.0000000000000474.   edoc
Favre-Godal, Q., Dorsaz, S., Queiroz, E. F., Marcourt, L., Ebrahimi, S. N., Allard, P.-M., Voinesco, F., Hamburger, M., Gupta, M. P., Gindro, K., Sanglard, D. and Wolfender, J.-L. (2015) ‘Identification of novel anti-Candida cassane type diterpenes from the roots bark of Swartzia simplex (Sw.) Spreng’, Journal of Natural Products. American Chemical Society, 78(12), pp. 2994-3004. doi: 10.1021/acs.jnatprod.5b00744.   edoc
Arnet, I., Seidling, H. M. and Hersberger, K. E. (2015) ‘Unerwünschte Arzneimittelwirkungen in der Offizinapotheke’, Therapeutische Umschau. Hans Huber, 72(11/12), pp. 687-692. doi: 10.1024/0040-5930/a000738.   edoc
Folzer, E., Khan, T., Schmidt, R., Finkler, C., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) ‘Determination of the Density of Protein Particles Using a Suspended Microchannel Resonator’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(12), pp. 4034-4040. doi: 10.1002/jps.24635.   edoc
Boll, B., Folzer, E., Finkler, C., Huwyler, J., Mahler, H.-C., Schmidt, R. and Koulov, A. V. (2015) ‘Comparative Evaluation of Two Methods for Preparative Fractionation of Proteinaceous Subvisible Particles-Differential Centrifugation and FACS’, Pharmaceutical research. Springer, 32(12), pp. 3952-3964. doi: 10.1007/s11095-015-1755-6.   edoc
Kaserer, T., Beck, K., Akram, M., Odermatt, A. and Schuster, D. (2015) ‘Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases’, Molecules. MDPI, 20(12), pp. 22799-22832. doi: 10.3390/molecules201219880.   edoc
Shelton, L. M., Lister, A., Walsh, J., Jenkins, R. E., Wong, M. H. L., Rowe, C., Ricci, E., Ressel, L., Fang, Y., Demougin, P., Vukojevic, V., O’Neill, P. M., Goldring, C. E., Kitteringham, N. R., Park, B. K., Odermatt, A. and Copple, I. M. (2015) ‘Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney’, Kidney international. Springer, 88(6), pp. 1261-1273. doi: 10.1038/ki.2015.286.   edoc
Becker, C., Wilson, J. C., Jick, S. S. and Meier, C. R. (2015) ‘Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: a case-control analysis’, International journal of cancer. Alan R. Liss, 137(10), pp. 2424-2431. doi: 10.1002/ijc.29601.   edoc
Seibert, J. K., Quagliata, L., Quintavalle, C., Hammond, T. G., Terracciano, L. and Odermatt, A. (2015) ‘A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer’, Cancer medicine. Wiley, 4(11), pp. 1717-1729. doi: 10.1002/cam4.517.   edoc
Di Chiara, M., Glaudemans, B., Loffing-Cueni, D., Odermatt, A., Al-Hasani, H., Devuyst, O., Faresse, N. and Loffing, J. (2015) ‘Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney’, American journal of physiology. Gastrointestinal and liver physiology. American Physiological Society, 309(9), pp. F779-F790. doi: 10.1152/ajprenal.00139.2015.   edoc
Becker, C., Jick, S. S., Meier, C. R. and Bodmer, M. (2015) ‘No evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: a case-control study’, BMC cancer. BioMed Central, 15, p. 719. doi: 10.1186/s12885-015-1719-6.   edoc
Haegler, P., Grünig, D., Berger, B., Krähenbühl, S. and Bouitbir, J. (2015) ‘Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: a cell model for idiosyncratic toxicity’, Toxicology. Elsevier, 336, pp. 48-58. doi: 10.1016/j.tox.2015.07.015.   edoc
Imfeld, P., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) ‘Benzodiazepine Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case-Control Analysis’, Drug safety. Adis International, 38(10), pp. 909-919. doi: 10.1007/s40264-015-0319-3.   edoc
Glanzmann, C., Frey, B., Meier, C. R. and Vonbach, P. (2015) ‘Analysis of medication prescribing errors in critically ill children’, European journal of pediatrics. Springer, 174(10), pp. 1347-1355. doi: 10.1007/s00431-015-2542-4.   edoc
Welzenbach, K., Mancuso, R. V., Krähenbühl, S. and Weitz-Schmidt, G. (2015) ‘A novel multi-parameter assay to dissect the pharmacological effects of different modes of integrin αLβ2 inhibition in whole blood’, British journal of pharmacology. Nature Publishing Group, 172(20), pp. 4875-4887. doi: 10.1111/bph.13256.   edoc
Allmendinger, A., Mueller, R., Huwyler, J., Mahler, H.-C. and Fischer, S. (2015) ‘Sterile Filtration of Highly Concentrated Protein Formulations: Impact of Protein Concentration, Formulation Composition, and Filter Material’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(10), pp. 3319-3329. doi: 10.1002/jps.24561.   edoc
Farimani, M. M., Bahadori, M. B., Koulaei, S. A., Salehi, P., Ebrahimi, S. N., Khavasi, H. R. and Hamburger, M. (2015) ‘New ursane triterpenoids from Salvia urmiensis Bunge: absolute configuration and anti-proliferative activity’, Fitoterapia. Elsevier, 106, pp. 1-6. doi: 10.1016/j.fitote.2015.07.017.   edoc
Du, K., De Mieri, M., Neuburger, M., Zietsman, P. C., Marston, A., van Vuuren, S. F., Ferreira, D., Hamburger, M. and van der Westhuizen, J. H. (2015) ‘Labdane and clerodane diterpenes from Colophospermum mopane’, Journal of Natural Products. American Chemical Society, 78(10), pp. 2494-2504. doi: 10.1021/acs.jnatprod.5b00729.   edoc
Bruderer, S. G., Bodmer, M., Jick, S. S. and Meier, C. R. (2015) ‘Poorly controlled type 2 diabetes mellitus is associated with a decreased risk of incident gout: a population-based case-control study’, Annals of the rheumatic diseases. British Medical Association, 74(9), pp. 1651-1658. doi: 10.1136/annrheumdis-2014-205337.   edoc
Werk, T., Huwyler, J., Hafner, M., Luemkemann, J. and Mahler, H.-C. (2015) ‘An Impedance-Based Method to Determine Reconstitution Time for Freeze-Dried Pharmaceuticals’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2948-2955. doi: 10.1002/jps.24443.   edoc
Folzer, E., Diepold, K., Bomans, K., Finkler, C., Schmidt, R., Bulau, P., Huwyler, J., Mahler, H.-C. and Koulov, A. V. (2015) ‘Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule’, Journal of pharmaceutical sciences. American Pharmaceutical Association, 104(9), pp. 2824-2831. doi: 10.1002/jps.24509.   edoc
Kunze, A., Poller, B., Huwyler, J. and Camenisch, G. (2015) ‘Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins’, Drug Metabolism and Personalized Therapy. de Gruyter, 30(3), pp. 175-188. doi: 10.1515/dmdi-2015-0003.   edoc
Hussner, J., Begung, R., Boettcher, K., Gliesche, D. G., Prestin, K. and Meyer zu Schwabedissen, H. E. (2015) ‘Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery’, Vascular Pharmacology . Elsevier, 72, pp. 25-34. doi: 10.1016/j.vph.2015.06.006.   edoc
Moridi Farimani, M., Abbas-Mohammadi, M., Esmaeili, M.-A., Salehi, P., Nejad-Ebrahimi, S., Sonboli, A. and Hamburger, M. (2015) ‘Seco-ursane type triterpenoids from Salvia urmiensis with apoptosis-inducing activity’, Planta medica. Thieme, 81(14), pp. 1290-1295. doi: 10.1055/s-0035-1546256.   edoc
Wilson, J. C., Toovey, S., Jick, S. S. and Meier, C. R. (2015) ‘Previously diagnosed influenza infections and the risk of developing epilepsy’, Epidemiology and infection. Cambridge University Press, 143(11), pp. 2408-2415. doi: 10.1017/S0950268814003380.   edoc
Bonifacio, A., Sanvee, G. M., Bouitbir, J. and Krähenbühl, S. (2015) ‘The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity’, Biochimica et biophysica acta. Elsevier, 1853(8), pp. 1841-1849. doi: 10.1016/j.bbamcr.2015.04.010.   edoc
Roberts, P. A., Bouitbir, J., Bonifacio, A., Singh, F., Kaufmann, P., Urwyler, A. and Krähenbühl, S. (2015) ‘Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency’, American journal of physiology. Gastrointestinal and liver physiology. American Physiological Society, 309(3), pp. E265-E274. doi: 10.1152/ajpendo.00001.2015.   edoc
Liakoni, E., Rätz Bravo, A. E. and Krähenbühl, S. (2015) ‘Hepatotoxicity of New Oral Anticoagulants (NOACs)’, Drug safety. Adis International, 38(8), pp. 711-720. doi: 10.1007/s40264-015-0317-5.   edoc
Oufir, M., Seiler, C., Gerodetti, M., Gerber, J., Fürer, K., Mennet-von Eiff, M., Elsas, S.-M., Brenneisen, R., von Mandach, U., Hamburger, M. and Potterat, O. (2015) ‘Quantification of burfadienolides in bryophyllum pinnatum leaves and manufactured products by UHPLC-ESIMS/MS’, Planta Medica. Georg Thieme Verlag, 81(12/13), pp. 1190-1197. doi: 10.1055/s-0035-1546126.   edoc
Du, K., De Mieri, M., Saxena, P., Phungula, K. V., Zietsman, P. C., Hering, S., van der Westhuizen, J. H. and Hamburger, M. (2015) ‘HPLC-​Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana’, Planta Medica. Georg Thieme Verlag, 81(12/13), pp. 1154-1162. doi: 10.1055/s-0035-1545929.   edoc
Allmendinger, A., Mueller, R., Schwarb, E., Chipperfield, M., Huwyler, J., Mahler, H.-C. and Fischer, S. (2015) ‘Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection’, Pharmaceutical research. Plenum Press, 32(7), pp. 2229-2240. doi: 10.1007/s11095-014-1611-0.   edoc
Bloechliger, M., Rüegg, S., Jick, S. S., Meier, C. R. and Bodmer, M. (2015) ‘Antipsychotic drug use and the risk of seizures: follow-up study with a nested case-control analysis’, CNS drugs. Springer, 29(7), pp. 591-603. doi: 10.1007/s40263-015-0262-y.   edoc
Layton, J. B., Meier, C. R., Sharpless, J. L., Stürmer, T., Jick, S. S. and Brookhart, M. A. (2015) ‘Comparative Safety of Testosterone Dosage Forms’, JAMA internal medicine. American Medical Association, 175(7), pp. 1187-1196. doi: 10.1001/jamainternmed.2015.1573.   edoc
Singh, F., Charles, A.-L., Schlagowski, A.-I., Bouitbir, J., Bonifacio, A., Piquard, F., Krähenbühl, S., Geny, B. and Zoll, J. (2015) ‘Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis’, Biochimica et biophysica acta. Molecular cell research. Elsevier, 1853(7), pp. 1574-1585. doi: 10.1016/j.bbamcr.2015.03.006.   edoc
Ślusarczyk, S., Topolski, J., Domaradzki, K., Adams, M., Hamburger, M. and Matkowski, M. (2015) ‘Isolation and fast selective determinatino of nor-abhietanoid diterpenoids from Perovskia atriplicifolia roots using LC-ESIMS/MS with multiple reaction monitoring’, Natural Product Communications . Natural Product Incorporation , 10(7), pp. 1149-1152.   edoc
Odermatt, A. and Klusonova, P. (2015) ‘11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story’, The journal of steroid biochemistry and molecular biology. Pergamon, 151, pp. 85-92. doi: 10.1016/j.jsbmb.2014.08.011.   edoc
Tsachaki, M., Birk, J., Egert, A. and Odermatt, A. (2015) ‘Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions’, Biochimica et biophysica acta. Molecular cell research. Elsevier, 1853(7), pp. 1672-1682. doi: 10.1016/j.bbamcr.2015.04.002.   edoc