Aktuelle Masterarbeitsthemen der Forschungsgruppe Biopharmazie
Current Master's Theses-Projects of the Research Group in Biopharmacy

 

Forschungsgebiet
Research Field
Kontakt Betreuer/in
Contact Supervisor
MSc PharmazieMSc Drug SciencesBemerkungen
Comments
Development of a Novel In Vitro Human Hepatocyte Model to Predict Drug Transport Alterations in Nonalcoholic Fatty Liver Disease (NAFLD)Contact person:
Dr. Jacqueline B. Tiley
yesyes

This work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description

Optimization of Liver Organoid Culture Conditions to Improve Transport Protein Levels and FunctionContact person:
Dr. Jacqueline B. Tiley
yesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
Optimization of Methods to Extract Transporter-Enriched Extracellular Vesicles from Various Biological SamplesDr. Jacqueline B. TileyyesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
Use of Endogenous Transporter Substrate Coproporphyrin-I to Assess Transporter Drug Interactions (tDIs) in VitroDr. Jacqueline B. TileyyesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
Light responsive approach to study NTCP regulation and functionDr. Jacqueline B. TileyyesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
     
No longer available
Investigating the influence of age and transporter genotypes on coproporphyrin levels in healthy children
Leila PotzelyesyesThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description
No longer available
Investigating the influence of OATP1B1 genetic variants on coproporphyrin uptake in vitro
Leila PotzelyesyesThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description
No longer available
Investigating solanidine as a biomarker to study phenoconversion of CYP2D6
Leila PotzelyesnoThis is a multidisciplinary project between the Biopharmacy and the Pharmaceutical Care Research Groups. The experimental part of this work (incl. UHPLC-MS/MS and genotyping) will be performed in the Biopharmacy laboratory at the University of Basel. Project description
No longer available
The role of Pgp genotype in Blood-Brain-barrier permeability for antidepressant drugs
Dr. Marta RyszyesnoThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description
No longer available
Effects of clinically used drugs on heme biosynthesis in various blood cell types isolated from umbilical cord blood
Dr. Karin BrechtyesyesThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description
No longer available
In the search of CYP2D6 biomarker: In-vitro metabolism of solanidine and other steroidal alkaloids
Dr. Marta RyszyesnoThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description
No longer available
Breaking New Ground in Phenotyping: Solanidine Metabolism as a CYP2D6 Activity Indicator
Nikolaos PaloumpisyesnoThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description