Aktuelle Masterarbeitsthemen der Forschungsgruppe Biopharmazie
Current Master's Theses-Projects of the Research Group in Biopharmacy

 

Forschungsgebiet
Research Field
Kontakt Betreuer/in
Contact Supervisor
MSc PharmazieMSc Drug SciencesBemerkungen
Comments

Natural product discovery pipeline to identify antidotes against amatoxin toxicity: Targeting OATP1B3-mediated uptake

Dr. Anima SchäfernoyesThis is a multidisciplinary project and the student will be supervised by both Anima Schäfer (Biopharmacy) and Eliane Garo (Pharmaceutical Biology). This project is therefore advertised in both groups. Project description
Views on the implementation of 3R in Switzerland: a qualitative explorationProf. Dr. Bernice ElgeryesnoThis work will be conducted at the Institute for Biomedical Ethics. Project description
Investigation of the ethical and moral values underpinning decision-making and approval of animal experiments in SwitzerlandProf. Dr. Bernice ElgeryesnoThis work will be conducted at the Institute for Biomedical Ethics. Project description
Development of a Novel In Vitro Human Hepatocyte Model to Predict Drug Transport Alterations in Nonalcoholic Fatty Liver Disease (NAFLD)Contact person:
Dr. Jacqueline B. Tiley
yesyes

This work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description

Optimization of Liver Organoid Culture Conditions to Improve Transport Protein Levels and FunctionContact person:
Dr. Jacqueline B. Tiley
yesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
Optimization of Methods to Extract Transporter-Enriched Extracellular Vesicles from Various Biological SamplesDr. Jacqueline B. TileyyesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
Use of Endogenous Transporter Substrate Coproporphyrin-I to Assess Transporter Drug Interactions (tDIs) in VitroDr. Jacqueline B. TileyyesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
Light responsive approach to study NTCP regulation and functionDr. Jacqueline B. TileyyesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
     
No longer available
Impact of long-term erlotinib treatment on CYPs in Slco2b1 -/- vs hSLCO2B1 +/+ rats
Dr. Marta RyszyesyesThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel.
Project description
No longer available
Mechanistic studies on the recently identified OATP2B1-CYP3A1 interplay
Contact person:
Prof. H. Meyer zu Schwabedissen
yesno

This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel.
Project description

No longer available
Investigation of OATP2B1 and OATP1A2 role in the transport of centrally active compounds at the Blood-Brain Barrier
Valerio TaggiyesyesOur project will focus on the role of the human OATP2B1 and OATP1A2 in the transport of centrally active drugs and endogenous compounds such as sulfated steroids at the Blood-Brain Barrier in vitro and in vivo. This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel.

No longer available
Impact of rifampicin on regulation of heme biosynthesis

Dr. Karin BrechtyesyesThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel.
Project description
No longer available
Establishment of an in vitro model to investigate the relevance of OATP2B1 in the regulation of drug metabolism
Dr. Anima SchäferyesnoThis work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel.
Project description

No longer available
Evaluation and implementation of model-based (Bayesian) vancomycin concentration monitoring in neonatology

Dr. Verena GottayesyesThis project will be conducted at the University Children’s Hospital in Basel in collaboration with the departments pediatric clinical pharmacy, pediatric pharmacology and pharmacometrics, and neonatology.
Project description
No longer available
Development of a Novel In Vitro Human Hepatocyte Model to Predict Drug Transport Alterations in Nonalcoholic Fatty Liver Disease (NAFLD)
Contact person:
Dr. Jacqueline B. Tiley
yesyesThis work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA
Project description
No longer available
Analysis of synthetic cannabinoids in urine
Dr. Manuela MontiyesyesMaster Thesis at the Institute of Forensic Medicine Basel