Aktuelle Masterarbeitsthemen der Forschungsgruppe Biopharmazie
Current Master's Theses-Projects of the Research Group in Biopharmacy
| Forschungsgebiet Research Field | Kontakt Betreuer/in Contact Supervisor | MSc Pharmazie | MSc Drug Sciences | Bemerkungen Comments |
|---|---|---|---|---|
| Development of a Novel In Vitro Human Hepatocyte Model to Predict Drug Transport Alterations in Nonalcoholic Fatty Liver Disease (NAFLD) | Contact person: Dr. Jacqueline B. Tiley | yes | yes | This work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA |
| Optimization of Liver Organoid Culture Conditions to Improve Transport Protein Levels and Function | Contact person: Dr. Jacqueline B. Tiley | yes | yes | This work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA Project description |
| Optimization of Methods to Extract Transporter-Enriched Extracellular Vesicles from Various Biological Samples | Dr. Jacqueline B. Tiley | yes | yes | This work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA Project description |
| Use of Endogenous Transporter Substrate Coproporphyrin-I to Assess Transporter Drug Interactions (tDIs) in Vitro | Dr. Jacqueline B. Tiley | yes | yes | This work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA Project description |
| Light responsive approach to study NTCP regulation and function | Dr. Jacqueline B. Tiley | yes | yes | This work will be conducted in the laboratories of the UNC Eshelman School of Pharmacy, USA Project description |
| No longer available Investigating the influence of age and transporter genotypes on coproporphyrin levels in healthy children | Leila Potzel | yes | yes | This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description |
| No longer available Investigating the influence of OATP1B1 genetic variants on coproporphyrin uptake in vitro | Leila Potzel | yes | yes | This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description |
| No longer available Investigating solanidine as a biomarker to study phenoconversion of CYP2D6 | Leila Potzel | yes | no | This is a multidisciplinary project between the Biopharmacy and the Pharmaceutical Care Research Groups. The experimental part of this work (incl. UHPLC-MS/MS and genotyping) will be performed in the Biopharmacy laboratory at the University of Basel. Project description |
| No longer available The role of Pgp genotype in Blood-Brain-barrier permeability for antidepressant drugs | Dr. Marta Rysz | yes | no | This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description |
| No longer available Effects of clinically used drugs on heme biosynthesis in various blood cell types isolated from umbilical cord blood | Dr. Karin Brecht | yes | yes | This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description |
| No longer available In the search of CYP2D6 biomarker: In-vitro metabolism of solanidine and other steroidal alkaloids | Dr. Marta Rysz | yes | no | This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description |
| No longer available Breaking New Ground in Phenotyping: Solanidine Metabolism as a CYP2D6 Activity Indicator | Nikolaos Paloumpis | yes | no | This work will be conducted in the laboratory of the Biopharmacy research group at the University of Basel. Project description |