Aktuelle Masterarbeitsthemen der Forschungsgruppe Molekulare Pharmazie
Current Master's Theses-Projects of the Research Group in Molecular Pharmacy
| Forschungsgebiet Research Field | Kontakt Betreuer/in Contact Supervisor | MSc Pharmazie | MSc Drug Sciences | Bemerkungen Comments |
|---|---|---|---|---|
| Point-of-Care-Diagnostics for Preeclampsia (Development of sensitive, antibody-based in-vitro diagnostic rapid tests) Project description English Project description German | Prof. Dr. Daniel Ricklin | nein | ja | External master’s thesis with MOMM Diagnostics GmbH and FHNW. Preferred project start in August 2021 or earlier; first contact Prof. Dr. Daniel Ricklin |
| Development of peptide-based strategies for host cell/biomaterial protection and targeting. | Clément Bechtler | ja | ja | |
| Development of Carbohydrate-based Mimics as Ligands for Siglec-8 | PD Dr. Oliver Schwardt | ja | nein | Project description |
| Evaluation of physiological or therapeutic immune modulators of the complement/coagulation system. | Dr. Richard Pouw | ja | ja | |
Synthesis and development of carbohydrate-based molecules to reduce pathogen virulence | Dr. Rachel Hevey | ja | ja | |
Design, synthesis, and evaluation of carbohydrate-based modulators of host defense | Dr. Rachel Hevey | ja | ja | |
| Synthesis and development of glycopolymers for treating blood group-incompatible transplantations | Dr. Rachel Hevey | ja | ja | Collaboration with University Start-up Polyneuron Pharmaceuticals AG |
| In vitro assessment of glycopolymers for enabling blood group-incompatible transplantations | Dr. Rachel Hevey | ja | ja | Collaboration with University Start-up Polyneuron Pharmaceuticals AG |
| Cloning, expression, purification and evaluation of therapeutically relevant proteins involved in the modulation of immune and inflammatory responses. | Dr. Said Rabbani | ja | ja | Project description |
| Discovery and evaluation of novel complement inhibitors using phage-display library screening and peptide synthesis. | Dr. Christina Lamers | ja | ja | |
| Development of a human stem cell-derived in vitro assay to assess the DMPK properties of new drug candidates | Dr. Pascal Hänggi | ja | ja | Collaboration with University Start-up Polyneuron Pharmaceuticals AG; first contact Prof. Dr. Daniel Ricklin and Dr. Pascal Hänggi |
| no longer available Preparation of protein-based targets and modulators of the innate immune system and their evaluation in bioassays. | Dr. Said Rabbani | ja | ja | |
| no longer available Design and synthesis of glycomimetic ligands for Siglec-8, a new target for eosinophil and mast-cell related disorders. | Benedetta Girardi | ja | ja | |
| no longer available Removal of autoantibodies against glycans - Biological and biophysical characterization of autoantibody-glycopolymer complexes | Butrint Aliu | ja | ja | Collaboration with University Start-up Polyneuron Pharmaceuticals AG; |
| no longer available Beyond anti-glycan autoantibody removal - In vivo and in vitro assessment of the immune modulatory potential of glycopolymers for the treatment of autoimmune diseases | Dr. Emilie Seydoux | ja | ja | Collaboration with University Start-up Polyneuron Pharmaceuticals AG; |
| no longer available Novel Anti-Inflammatories: Identification of Selectin Antagonists by a Dynamic Combinatorial Chemistry Approach | Prof. em. Dr. Beat Ernst | ja | ja | preferred MSc Drug Sciences |
| no longer available Evaluation and Summarization Praktikum | PD Dr. Oliver Schwardt | ja | ja | |
no longer available | Prof. Dr. Daniel Ricklin | ja | ja | Collaboration with Universitätsspital Basel Project description |
| no longer available Establishment and validation of a Mannan-induced psoriasis arthritis-like disease model in mice | Prof. Dr. Daniel Ricklin | nein | ja | Masterthesis with Idorsia; first contact Prof. Dr. Daniel Ricklin |
no longer available | Carla Plüss | ja | ja | |
| no longer available Protein engineering for the development of inhibitors of host defense pathway initiation. | Kevin Widmer | ja | ja | |
| no longer available Discovery and synthesis of CD59 inhibitors to potentiate antibody-based leukemia treatment | Dr. Christina Lamers | ja | ja | |
| no longer available DC-SIGN Antagonists to Block the Viral Entry to Dendritic Cells | Dr. Jonathan Cramer | ja | ja | preferred MSc Drug Sciences |