06 April 2020 / Research

Structure-Elucidating Total Synthesis of the (Polyenoyl)tetramic Acid Militarinone C

The (polyenoyl)tetramic acid militarinone C (1) heads a family of seven members. Before our work, the configuration of C-5 was unknown whereas the configurations of C-8′ and C-10′ were either (R,R) or (S,S). We synthesized the four stereoisomers of constitution 1, which conform with these insights. More