Dr. Andreas Maximilian Dietl
Technology / laboratory / infrastructureTechnology / laboratory / infrastructure
Klingelbergstrasse 50
4056
Basel
Schweiz
Curriculum Vitae
Andreas Dietl is a Research Technician specializing in biochemistry, molecular biology, and structural biology. He obtained his B.Sc. in Chemistry from Heidelberg University in 2009, where he focused on biochemical and biophysical studies of the Amyloid Precursor Protein (APP) in complex with the adaptor protein Fe65-PTB2, relevant to Alzheimer's disease research. Continuing at Heidelberg University, he earned his M.Sc. in Molecular Biosciences in 2012, working on the structural characterization of octaheme c-type cytochromes from Kuenenia stuttgartiensis. In 2016, he completed his PhD in Biology at the Max Planck Institute for Medical Research, investigating the structural and mechanistic aspects of proteins from anaerobic ammonium-oxidizing bacteria.
Currently, Andreas manages laboratory operations, including procurement and instrument maintenance, and is involved in teaching tasks. He actively participates in several research projects, such as polyketide biosynthesis, and provides NMR analyses for external collaborators. His expertise includes recombinant protein expression and purification, synthesis of small organic molecules, and a range of analytical chemistry techniques like NMR, GC/MS, HPLC/MS, UV/Vis, and IR spectroscopy.
Publication(s):
Dietl et al. (2015): The inner workings of the hydrazine synthase multiprotein complex. Nature, 527, p. 394-397. Available at: https://doi.org/10.1038/nature15517.
Chicano et al. (2021): Structural and functional characterization of the intracellular filament-forming nitrite oxidoreductase multiprotein complex. Nature Microbiology, 6, p. 1129-1139. Available at: https://doi.org/10.1038/s41564-021-00934-8.
Dietl et al. (2023): Structures of an unusual 3-hydroxyacyl dehydratase (FabZ) from a ladderane-producing organism with an unexpected substrate preference. Journal of Biological Chemistry, 299 (5), p. 104602. Available at: https://doi.org/10.1016/j.jbc.2023.104602.